posterior abdominal wall is most important chapter in undergraduate curriculum.After read the above presentation you have to able describe about posterior abdominal wall structures like Muscles ,Bony part and Ligamental part. Then nervous innervation of Lumbarplexus and Autonomic nervous system of posterior abdominal wall including sympathetic chain
posterior abdominal wall is very important structure in abdomen.in this presentation we have to see detailed about posterior abdominal wall muscles .lumbar plexus and nerve supply of posterior abdominal wall .including autonomic sympathetic chain.
posterior abdominal wall is very important structure in abdomen.in this presentation we have to see detailed about posterior abdominal wall muscles .lumbar plexus and nerve supply of posterior abdominal wall .including autonomic sympathetic chain.
Above power point wil give detailed explanation aboutthe cubital fossa.knowledge of this cubital fossa is clinically very important for all clinicians.
This presentation will give orientation to the basic anatomy of liver. The segmental anatomy of liver will give strong and basic anatomy knowledge to surgeons.
this presentation give detailed information about posterior compartment of arm.After read this presentation you have describe about muscles of posterior compartment of arm and blood supply and nervous innervation , action of posterior compartment.Also clinical importance of posterior compartment
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
1. POSTERIOR ABDOMINAL WALL
THORACOLUMBAR FASCIA (AN 45.1)
MUSCLES (AN 45.3)
LUMBAR PLEXUS AND ABDOMINAL PART OF AUTONOMIC
SYSTEM (AN 47.12)
Dr .M.Vasanthakohila
Post graduate Department ofAnatomy
Kilpauk medical college
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12. THORACOLUMBAR FASCIA
• It is divided into 2 parts –
lumbar and thoracic
• Lumbar fascia is the deep
fascia enclosing the deep
muscles of the back
• It is made up of 3 layers -
posterior, middle and
anterior
• It fills the gap between
12th rib and iliac crest
13. Contd…
• The posterior layer is
thickest and the
anterior layer is
thinnest
• The posterior layer
covers the loin and is
continued upwards on
the back of the thorax
and neck
• The middle and anterior
layers are confined to the
lumbar region
14. Contd…
• Between the posterior and
middle layers lie the erector
spinae and transversus
spinalis muscles
• Between the middle and
anterior layers lies the
quadratus lumborum muscle
• The 3 layers fuse laterally to
form a dense aponeurotic
sheet which gives origin to
the internal oblique and
transversus abdominis
muscles
15. POSTERIOR LAYER
• Medially - the layer is attached
to the tips of the lumbar and
sacral spines and the
interspinous ligaments.
• Laterally - it blends with the
middle layer at the lateral
border of the erector spinae.
• Superiorly - it continues on to
the back of the thorax where it
is attached to the vertebral
spines and the angles of the
ribs.
• Inferiorly - it is attached to the
posterior one-fourth of the
outer lip of the iliac crest.
16. MIDDLE LAYER
• Medially - the layer is attached to
the tips of the transverse
processes of first lumbar vertebra
and the inter-transverse
ligaments.
• Laterally - it blends with the
anterior layer at the lateral
border of the quadratus
lumborum.
• Superiorly - it is attached to the
lower border of the 12th rib and
to the lumbocostal ligament.
• Inferiorly - it is attached to the
posterior part of the intermediate
area of the iliac crest.
17. ANTERIOR LAYER
• Medially - the layer is attached
to the vertical ridges on the
anterior surface of the transverse
processes of first lumbar
vertebra.
• Laterally - it blends with the
middle layer at the lateral border
of the quadratus lumborum.
• Superiorly - it forms the lateral
arcuate ligament, extending from
the tip of the first lumbar
transverse process to the 12th
rib.
• Inferiorly - it is attached to the
inner lip of the iliac crest and the
iliolumbar ligament.
18.
19.
20.
21.
22.
23.
24.
25. Iliohypogastric Nerve (L1)
• The nerve emerges @ the
lateral border of the psoas
major, runs downwards
and laterally in front of the
quadratus lumborum, and
behind the kidney and
colon, pierces the
transversus abdominis a
little above the iliac crest,
and runs in the abdominal
wall supplying the
anterolateral muscles.
26. Ilioinguinal Nerve (L1)
• The ilioinguinal
nerve (L1) has the
same course as the
iliohypogastric
nerve, but on a
slightly lower level
• It exits through
superficial inguinal
ring
27. ILIOINGUNIAL NERVE INNERVATIONS
MOTOR INERVATION
• INTERNAL OBLIQUE
MUSCLE
• TRANSVERSE ABDOMINIS
MUSCLE
SENSORY INNERVATION
• UPPER AND MDIAL ASPECT
OF THIGH
• SCROTUM AND ROOT OF
PENIS IN MALE
• MONS PUBIS AMD LABIA
MAJUS IN FEMALE
28. Genitofemoral nerve
• The nerve emerges on the
anterior surface of the psoas
muscle near its medial border
and runs downwards in front of
the muscle
• Near the deep inguinal ring it
divides into femoral and genital
branches
• The femoral branch passes
through the arterial
compartment of the femoral
sheath and is distributed to the
skin of the upper part of the
front of the thigh
29. Contd…
• The genital branch pierces
the psoas sheath and
enters the inguinal canal
through the deep inguinal
ring
• In the male, it supplies the
cremaster muscle, and in
the female, it gives sensory
branches to the round
ligament of the uterus and
to the skin of the labium
majus
30. Lateral cutaneous nerve of the thigh
• The nerve of the thigh
(L2, L3; dorsal divisions)
emerges at the lateral
border of the psoas, runs
downwards and laterally
across the right iliac
fossa, over the iliacus
and reaches the anterior
superior iliac spine
• Here it enters the thigh
by passing behind the
lateral end of the
inguinal ligament
31. Femoral nerve
• The femoral nerve (L2, L3, L4; dorsal divisions) emerges at
the lateral border of the psoas below the iliac crest, and runs
downwards and slightly laterally in the furrow between the
psoas and iliacus
• It lies under cover of the fascia iliaca
• It passes deep to the inguinal ligament to enter the thigh
lying on the lateral side of the femoral sheath
• Before entering the thigh it supplies the iliacus and
pectineus
• In thigh it supplies quadriceps femoris and sartorius
32. Obturator nerve
• The obturator nerve (L2, L3, L4; ventral divisions)
emerges on the medial side of the psoas muscle and
runs forwards and downwards on the pelvic wall,
below the pelvic brim
• Near its commencement it is crossed by the internal
iliac vessels and the ureter.
• It enters the thigh by passing through the obturator
canal.
• It supplies 3 adductor muscles, obturator externus
and gracilis.
Editor's Notes
Action –weak flexor of trunk
Medial border of psoas major
Accessory obturator nerve
Skin of gluteal region and hypogastric region of anterior abdominal wall