The document discusses examining the skin and appendages of animals clinically. It describes how the condition of the skin reflects general animal health and can provide diagnostic clues. Specific things to examine include coat condition, elasticity, lesions, dermatitis, parasites, and discoloration which may indicate illnesses. Procedures include grasping the skin to check elasticity and visual exam of the coat and lesions. Primary skin lesions include spots, papules, vesicles, blisters and pustules while secondary lesions can include erosions, ulcers, and crusts.
Mange is among the common illnesses that many dog owners are concerned about. People usually get tensed and do not know how to handle such situations. I present you this Presentation that speaks about Mange, a skin disease caused by tiny parasite mites on dogs. You can refer to this to know what Mange is all about, the types of Mange, the causes, the symptoms and a few easy ways to deal with it. Mange, if left untreated can be fatal. Therefore, timely knowledge and treatment about this disease is important. You can also add your views in the comments below.
For more information about Mange, you can refer to the following links:
http://www.vet-organics.com/types-of-mange-in-dogs/
http://pets.webmd.com/dogs/mange-dogs-canine-scabies
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Mange is among the common illnesses that many dog owners are concerned about. People usually get tensed and do not know how to handle such situations. I present you this Presentation that speaks about Mange, a skin disease caused by tiny parasite mites on dogs. You can refer to this to know what Mange is all about, the types of Mange, the causes, the symptoms and a few easy ways to deal with it. Mange, if left untreated can be fatal. Therefore, timely knowledge and treatment about this disease is important. You can also add your views in the comments below.
For more information about Mange, you can refer to the following links:
http://www.vet-organics.com/types-of-mange-in-dogs/
http://pets.webmd.com/dogs/mange-dogs-canine-scabies
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Paratuberculosis is a contagious, chronic and sometimes fatal infection that primarily affects the small intestine of ruminants.
It is caused by the bacterium Mycobacterium avium subspecies paratuberculosis.
Infections normally affect ruminants (mammals that have four compartments of their stomachs, of which the rumen is one),
but have also been seen in a variety of non ruminant species, including rabbits, foxes, and birds. Horses, dogs, and nonhuman primates have been infected experimentally.
Paratuberculosis is found worldwide
Diagnosis and Treatment of Canine Pyodermaupstatevet
Ed Jazic, DVM, DACVD
The prevalence of Canine Pyoderma is increasing very quickly and the clinical condition can present in a variety of ways. It is a common secondary manifestation of a variety of clinical conditions like allergic skin diseases, endocrinopathies, autoimmune skin diseases, and keratinization disorders. An efficient and correct diagnosis is essential as is proper therapy in the face of ever-increasing development of Canine Methicillin-Resistant Staphylococcal Pyoderma.
www.petsgroomingtips.com is one of the front-runners in providing complete digital information to the pet owners, which would guide theme through various process of grooming their beloved kids. A shabby puppy or kitten not only appears dirty but soon infested with disease if not treated properly. Our various tutorials and free PDF guides cover every aspect of the grooming process.
Psoriasis is a chronic autoimmune skin disorder characterized by the rapid and excessive growth of skin cells. It affects around 2-3% of the global population and can manifest in various forms, from mild to severe. This condition is often associated with genetic factors and involves the immune system mistakenly attacking healthy skin cells.
Paratuberculosis is a contagious, chronic and sometimes fatal infection that primarily affects the small intestine of ruminants.
It is caused by the bacterium Mycobacterium avium subspecies paratuberculosis.
Infections normally affect ruminants (mammals that have four compartments of their stomachs, of which the rumen is one),
but have also been seen in a variety of non ruminant species, including rabbits, foxes, and birds. Horses, dogs, and nonhuman primates have been infected experimentally.
Paratuberculosis is found worldwide
Diagnosis and Treatment of Canine Pyodermaupstatevet
Ed Jazic, DVM, DACVD
The prevalence of Canine Pyoderma is increasing very quickly and the clinical condition can present in a variety of ways. It is a common secondary manifestation of a variety of clinical conditions like allergic skin diseases, endocrinopathies, autoimmune skin diseases, and keratinization disorders. An efficient and correct diagnosis is essential as is proper therapy in the face of ever-increasing development of Canine Methicillin-Resistant Staphylococcal Pyoderma.
www.petsgroomingtips.com is one of the front-runners in providing complete digital information to the pet owners, which would guide theme through various process of grooming their beloved kids. A shabby puppy or kitten not only appears dirty but soon infested with disease if not treated properly. Our various tutorials and free PDF guides cover every aspect of the grooming process.
Psoriasis is a chronic autoimmune skin disorder characterized by the rapid and excessive growth of skin cells. It affects around 2-3% of the global population and can manifest in various forms, from mild to severe. This condition is often associated with genetic factors and involves the immune system mistakenly attacking healthy skin cells.
In this slide Structure of Skin and Hair, Hair Growth Cycle were described followed by skin related diseases such as Acne, dry skin, pigmentation, wrinkles etc.
Respiration, types of respiration, examination of mucous membrane, changes of color , examination of lymph-nodes, examination of skin and associated structures
Structure of skin relating to problems like dry skin, acne vulgaris, pigmenta...Jaswanth Gowda BH
This single presentation contains a complete information about structure of skin and its relating to problems such as dry skin, acne vulgaris, pigmentation, prickly heat, wrinkles, body odour, structure of hair and hair growth cycle, oral cavity problems.
A comprehensive presentation about Psychocutaneous disorders taken from Rook's textbook of dermatology, along with tables and pictures. Useful for dermatologists and other healthcare professionals.
ealthupshot is your one platform destination to satiate your brain cells as well as your heart with an array of unheard stories in Entertainment, Lifestyle, Food Factory, Fashion, Beauty and not to forget the social responsibility via Social Spotlight.
https://www.slideshare.net/
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
2. 1. The skin provides protection against minor physical injuries
supports hair growth and offers some defences against
microbial invasion.
2. The condition of the skin is a reflection of the general health
of the animal, deteriorating in cases of ill health, ill thrift and
debility.
3. In some conditions, such as jaundice, the skin may provide
through discolouration direct diagnostic evidence of a specific
disease process.
4. In other conditions, such as parasitism or severe mineral
deficiency, a nonspecific general deterioration of skin health
may occur causing a greater number of hairs than normal to
enter the telogen or resting phase and a delay in their
replacement, leaving the coat in poor condition with little hair.
3. 5. Sebaceous secretions may be reduced, allowing the skin to
become abnormally dry and inflexible and less able to perform its
normal defences role in an already debilitated animal.
6. In other cases, sebaceous secretion increases causing the skin
to have either a greasy or a dry seborrhoeic, flaky Appearance.
7. Structures or parts associated with skin as its appendages are
hoofs, hairs, horns, quills, claws, nails, sebaceous glands and
sweat glands.
8. Discrete skin lesions range in type from urticarial plaques to
the circumscribed scabs of ringworm, pox and impetigo.
9. Diffuse lesions include the obvious enlargements due to
subcutaneous edema, hemorrhage and emphysema.
10. Enlargements of lymph nodes and lymphatics are also evident
when examining an animal from a distance.
4. The perspective point to assessing the
condition of skin and coat to identify
clinical signs of skin lesions such as:
•Condition of the coat
11. Other skin lesions:
1. Discoloration of the skin may arise due to
anaemia, cyanosis, jaundice, hyperaemia.
2. In febrile conditions hair may be erect and
in all chronic diseases with disturbances in
nutrition, hair become rough, lusterless dry
and coarse.
3. Alopecia (Loss of hair) may occur due to
diseases like ring worm, scabies, eczema,
Iodine and Vit A deficiencies,
12. Procedure of the examine the skin and coat:
1. grasp the skin of the upper part of
the body and notice the elasticity,
2. visual inspection of the condition of
the coat
3. presence of skin lesions should be
noted.
13. primary and secondary skin lesions
and
may
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ation
hairs
ay in
ittle
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orm
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ance
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ands
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ents
ema.
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Table 7: Examples of primary and secondary skin lesions.
Primary skin
lesions
Description Examples
Secondary
skin lesions
Notes
Spot
Circumscribed red area
of skin which is not
elevated or swollen
Flea bites Erosion
Destructive
separation of
the epidermis
(contagious
pustular
dermatitis of
sheep and goat).
Papule
Firm elevation of skin
surface caused by
cellular infiltration
Pox Ulcer
Circumscribed
shallow
destructive
area of tissue
with or without
elevated edges
(equine ulcerative
lymphangitis)
Vesicle
Elevation of superficial
layer of skin with
accumulation of serous
fluid beneath it.
FMD,
vascular
stomatitis,
pox
Crust
A firm mthass
consisting of dry
inflammatory
exudate or blood.
Blister A large vesicle Dandruff
Secondary to
ectoparasites
Pustule A pus-filled vesicle