The document discusses approaches and methods for plaque control. There are two basic approaches: mechanical and chemical. Mechanical plaque control involves toothbrushing and using interdental aids like floss or brushes. Chemical plaque control uses antimicrobial agents applied to the teeth, including antibiotics, enzymes, quaternary ammonium compounds, bisbiguanides, metallic salts, herbal extracts, and fluorides. The document provides details on toothbrush design standards and proper brushing technique to effectively remove plaque.