Vitamin B2, also known as riboflavin, is required for metabolism and energy production. Good dietary sources include milk, cheese, eggs, leafy greens, almonds, and soybeans. The recommended daily amount is 1.5 mg. Riboflavin is absorbed in the small intestine and circulates in the active forms FMN and FAD, which act as coenzymes in over 150 oxidation-reduction reactions involved in metabolism. Deficiency can cause symptoms like cracked lips, inflammation of the tongue, mouth ulcers, dry and scaling skin, and eye irritation.

1. Vitamin B2
Riboflavin
Dr. Muhammad Sarfraz
M.B.B.S., M.Phil.(Pharmacology)
Senior Demonstrator
Quaid-e-Azam Medical College Bahawalpur, pakistan.

2. Vitamin B2
Riboflavin
2

3. Natural Sources
MILK
CHEESE
EGG WHITE
LIVER.
LEAFY GREEN VEGETABLES
ALMONDS
SOYBEANS
YEAST
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6. Required Daily Amount
1.5 mg/day
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7. Absorbed in small
intestine and distributed
to all tissues by
circulation.

8. Role of Vitamin B2
ACTIVE FORMS:
• Riboflavin-Mononucleotide
(FMN).
• Riboflavin-Adenine Dinucleotide
(FAD).
8

9. FMN
FAD

10. Active forms of riboflavin are FMN and
FAD.
They act as prosthetic groups of
several enzymes.
Catalyzes oxidation-reduction
reactions.
Growth, repair, development of
body tissues - healthy skin,
eyes and tongue

11. Role of Vitamin B2
The Active Forms Work As
Co-enzymes For About
→ 150 ←
Oxidation - Reduction Reactions
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12. Role of Vitamin B2
Involved In
• Carbohydrate, Proteins And Fat
Metabolism
• Activation Of Vitamin B12 And
Folate.
• Protection Of Erythrocytes And
Other Cells From Oxidative Stress.
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14. Absorption
• Riboflavin Is Absorbed In The Proximal Intestine
• Riboflavin Is Stored
In
Liver, Kidney and Heart
As
FAD
(70- 90%)
Or
FMN Or
Riboflavin
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15. Causes of Riboflavin Deficiency
Not Getting Enough Of The Vitamin
From The Diet.
A Result Of Conditions That Affect
Absorption In The Intestine.
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16. Causes of Riboflavin Deficiency
The Body Not Being Able To Use The
Vitamin.
An Increase In The Excretion Of The
Vitamin From The Body.
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17. Deficiency symptoms
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Oral
•Angular
Stomatitis
•Cheilosis
•Glossitis

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Facial •Dermatitis Of
Nasolabial
Region.

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Ocular •Vascularization Of
Cornea

21. Deficiency symptoms
• Angular Cheilitis
(Fissuring At The Corners Of The
Mouth)
Cracked And Red Lips.
• Glossitis
Inflammation Of The Lining Of
Mouth And Tongue
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22. Deficiency symptoms
• Mouth Ulcers
DryAnd Scaling Skin
 Seborrheic Dermatitis
The Eyes Become
Bloodshot
Itchy
Sensitive To Bright Light 22

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