Sapling Learning Select the statements that explain why duplication is a driving force for evolution and the generation of genes. variations can occur when random fixed mutations are introduced into a new chromosomal Duplication of a gene segment always results in novel phenotypes. Duplicated genes provide extra copies of DNA that are not constrained by an essential function. Genes duplicate then diverge from the original sequence to create novel genes and Solution Statement No. 1, 3 and 4 justify the fact that Gene duplication driving force behind Evolution. 1) Occurence of fixed mutation in new genotypic environment result may result into deletion of another gene function or enhancement of gene responsible for a particular phenotype. this enhancement (example curvature of spine and straightening of posture) or deletion (example disappearance of tail) can be beneficial to the organism and is passed to future generations thus leading to evolution of new species. 2) Duplicate copies of DNA, after a period of time, are often rendered redundant and are no longer constrained by any essential function. These redundant copies often result in acquiring new function and lead to evolution. 3) Gene duplication, followed by their divergence leads to formation of novel genes and take part in evolution. 4) Novel gene generation result may from interaction between two different genes. However, it is not always that duplication of a gene will always result in new phenotypes. Thus, Statement 1,3 and 4 are true to the statement that gene duplication result into evolution and generation of new genes..