Which of the following is NOT a rationale for using mRNA intermediates in gene expression? to preserve its original, pristine copy of the gene DNA lacks the necessary information for protein production. to amplify the response to its changing needs to connect the information (DNA) with protein-producing organelles (ribosomes) Solution Answer b) DNA lacks the necessary information for protein production. Reason - This is not true because DNA contains all the necessary information required to code all the proteins. the same information is being transcribed on mRNA molecule during transcription process and the same information is translated into an amino acid sequence from mRNA into protein. in fact, DNA contains all the necessary information for protein production..