Hyaluronic Acid - What is it, sources, side effects and it's applications.

1. Hyaluronic
Acid

2. Overview
 What is HA?
 Structure & Function
 Benefits
 Side Effects
 Sources
 Applications

3. What is HA?
 HA (Hyaluronic acid) is also called
Hyaluronan and Restylane is the
trade name.
 It’s a viscous fluid carbohydrate
present in connective tissue, synovial
fluid, and the humors of the eye.
 Discovered in 1934 by Karl Meyer
 Found in all vertebrate animals

4. Structure & Function
 HA is a mucopolysaccharide.
 Composed of alternating residues of the
monosaccharides glucuronic acid and glucosamine.
 Forms hydrogen bond with water molecules.
 It is present as “filling material” in connective tissues
especially the skin.

5. Structure & Function
 Helps in delivering nutrients
 HA helps to retain over a 1000 times its
weight in water within the cells of skin.

6. Benefits
 Hydrates dry skin
 Makes skins soft & smooth
 Reduces fine lines & wrinkles
 Promotes hair growth
 Reconstructs connective tissue
 Used in eye surgery and corneal transplant.
 Used to treat Osteoarthritis by injecting it into the
joint.

7. Side Effects
 Sometimes hyaluronic acid can cause pain and redness
where it is injected.
 Increased pressure in the eye may occur after hyaluronic
acid is used for eye surgery.
 Rarely, hyaluronic acid may cause allergic reactions.

8. Sources
 Foods
Rooster comb, Beans, Satoimo,…
 Capsules
 Creams
 Serum
 Spray
 Injections

9. Applications
 Anti-Aging
 Joint Function Improvement
 Lip Augmentation

10. Anti-Aging
 HA decreases by aging, therefore wrinkles and folds
form.

11. Anti-Aging
 Skin with high hyaluronic
acid content
 Skin with low hyaluronic acid
content

12. Anti-Aging
 The fillers are available in the form of a
syringe.

13. Anti-Aging

14. Anti-Aging
Case #1

15. Anti-Aging
Case #2

16. Joint Function Improvement
 Joint fluid and articular cartilage
contain hyaluronic acid at high
concentration. It serves as a
lubricant (preventing bone-to-bone
friction) and as a cushion. This
function allows our joints to move
smoothly.

17. Treatment
 A common medical treatment uses HA as a
joint function improving agent. HA is injected
into joints to treat patients suffering from knee
osteoarthritis, periarthritis of the shoulder and
knee pain from rheumatoid arthritis. HA has
been reported to have anti-inflammatory and
pain relieving effects in such uses.

18. Lip Augmentation
 non-surgical procedure
that aims to improve the
appearance of the lips
by increasing their
fullness through
enlargement .

19. Lip Augmentation

20. END