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Gene regulation in eukaryotes in a nutshell covering all the important stages of gene regulation in eukaryotes at transcriptional level, translation level and post-translational level.
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Most bacteria are free-living organisms that grow by increasing in mass and then divide by binary fission. Growth and division are controlled by genes, the expression of which must be regulated appropriately. Genes whose activity is controlled in response to the needs of a cell or organism are called regulated genes. All organisms also have a large number of genes whose products are essential to the normal functioning of a growing and dividing cell, no matter what the conditions are. These genes are always active in growing cells and are known as constitutive genes or housekeeping genes; examples include genes that code for the enzymes needed for protein synthesis and glucose metabolism. Note that all genes are regulated on some level. If normal cell function is impaired for some reason, the expression of all genes, including constitutive genes, is reduced by regulatory mechanisms. Thus, the distinction between regulated and constitutive genes is somewhat arbitrary.
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1.Definition 2.Transcription is selective 3.Transcription in Prokaryotes •Initiation •Elongation •RNA polymerase vs DNA polymerase •Termination 4.Transcription in Eukaryotes •Initiation •Elongation •Termination •Post transcriptional modifications
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Gene regulation is how a cell controls which genes, out of the many genes in its genome, are "turned on" (expressed). Thanks to gene regulation, each cell type in your body has a different set of active genes – despite the fact that almost all the cells of your body contain the exact same DNA. These different patterns of gene expression cause your various cell types to have different sets of proteins, making each cell type uniquely specialized to do its job. [Source: https://www.khanacademy.org/science/biology/gene-regulation/gene-regulation-in-eukaryotes/a/overview-of-eukaryotic-gene-regulation]
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Gene regulation in eukaryotes in a nutshell covering all the important stages of gene regulation in eukaryotes at transcriptional level, translation level and post-translational level.
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Most bacteria are free-living organisms that grow by increasing in mass and then divide by binary fission. Growth and division are controlled by genes, the expression of which must be regulated appropriately. Genes whose activity is controlled in response to the needs of a cell or organism are called regulated genes. All organisms also have a large number of genes whose products are essential to the normal functioning of a growing and dividing cell, no matter what the conditions are. These genes are always active in growing cells and are known as constitutive genes or housekeeping genes; examples include genes that code for the enzymes needed for protein synthesis and glucose metabolism. Note that all genes are regulated on some level. If normal cell function is impaired for some reason, the expression of all genes, including constitutive genes, is reduced by regulatory mechanisms. Thus, the distinction between regulated and constitutive genes is somewhat arbitrary.
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1.Definition 2.Transcription is selective 3.Transcription in Prokaryotes •Initiation •Elongation •RNA polymerase vs DNA polymerase •Termination 4.Transcription in Eukaryotes •Initiation •Elongation •Termination •Post transcriptional modifications
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Gene regulation is how a cell controls which genes, out of the many genes in its genome, are "turned on" (expressed). Thanks to gene regulation, each cell type in your body has a different set of active genes – despite the fact that almost all the cells of your body contain the exact same DNA. These different patterns of gene expression cause your various cell types to have different sets of proteins, making each cell type uniquely specialized to do its job. [Source: https://www.khanacademy.org/science/biology/gene-regulation/gene-regulation-in-eukaryotes/a/overview-of-eukaryotic-gene-regulation]
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Presence of nucleus and complexity of eukaryotic organism demands a well controlled gene regulation in eukaryotic cell. Tissue specific gene expression is essential as they are multicellular organisms in which different cells perform different functions. This PPT deals with various control points for the gene regulation and expression within a cell.
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Basics of Undergraduate/university fellows Transcription is more complicated in eukaryotes than in prokaryotes because eukaryotes possess three different classes of RNA polymerases and because of the way in which transcripts are processed to their functional forms. More proteins and transcription factors are involved in eukaryotic transcription.
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Eukaryotic Gene Regulation
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Eukaryotic Gene Regulation
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A Family of
Identical Genes for rRNA
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11.
Globin Gene Evolution
12.
13.
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17.
Retrotransposon Movement
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
Enhancer Action
30.
31.
Types of DNA
Binding Domains
32.
33.
34.
35.
Alternative RNA Splicing
36.
37.
38.
39.
Protein Degradation by
a Proteasome
Download now