Regulation of gene expression in eukaryotes

Regulation of Gene Expression in Eukaryotes How does a eukaryotic organism regulate the expression of gene leading to the production of correct protein?

Expression of Different Genes ,[object Object],[object Object],[object Object],[object Object]

Mechanism of Gene Regulation in Prokaryotes and Eukaryotes ,[object Object],[object Object]

Check Points for Gene Expression in Eukaryotes ,[object Object],[object Object],[object Object]

1.Chromatin Structure ,[object Object],[object Object],[object Object]

1.Chromatin Structure ,[object Object],[object Object],[object Object],[object Object]

1.Chromatin Structure ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2.Regulation of Transcription ,[object Object],Regulation by repressors is very occasional and the primary role of regulation is played by the transcriptional activators known as transcription factors. These genes are primarily regulated by repressors. Eukaryotic genes are not organized into operons and each of these genes requires its own promoter. The linked genes are organized into clusters known as operons which are under the control of a single promoter. Eukaryotes Prokaryotes

2.Regulation of Transcription Monocistronic mRNAs which can produce a single polypeptide are produced A single operon gets transcribed into a polycistronic mRNA which can be translated into multiple proteins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A promoter sequence which controls an operon lies upstream of the operon. Accessory or the regulatory proteins control the recognition of the transcriptional initiation sites by RNA polymerases Eukaryotes Prokaryotes

2.Regulation of Transcription ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2.Regulation of Transcription ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2.Regulation of Transcription ,[object Object],[object Object],[object Object],[object Object]

2.Regulation of Transcription ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2.Regulation of Transcription ,[object Object],[object Object],[object Object]

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3.Regulation of RNA Processing ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Exon Shuffling ,[object Object]

4.Regulation of RNA Transport ,[object Object]

5.Regulation of RNA Longevity ,[object Object],[object Object],[object Object],[object Object]

6.Regulation of Translation ,[object Object],[object Object],[object Object],[object Object]

7.Post Translational Control Points ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Summary of the Class ,[object Object],[object Object],[object Object],[object Object],[object Object]

Regulation of gene expression in eukaryotes

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Regulation of gene expression in eukaryotes