This document summarizes radiological imaging of gastrointestinal stromal tumors (GISTs). It describes GISTs as the most common mesenchymal tumors of the GI tract, occurring most often in older adults. Imaging findings are discussed for various modalities including CT, MRI, US, and PET. Characteristic features include soft tissue masses arising from the GI tract wall. Larger tumors may show necrosis, hemorrhage, or cystic changes. Imaging can also detect metastatic lesions or tumor response to chemotherapy.