This document outlines workflows for publishing data at Scientific Data, including:
- Requiring a data PID for manuscript submission, enforcing data citation policies, and using structured repositories to capture subject-specific metadata.
- A data curation editor curates discovery-level metadata regardless of repository and machine readable metadata aids discovery.
- Data descriptors are designed to encourage full data documentation and linked analyses are captured to provide additional context.
The challenge of sharing data well, how publishers can helpVarsha Khodiyar
Researchers, academic institutes and funders are increasingly recognizing the importance of data sharing for reproducible science. However, it is not always straightforward and clear to researchers as to how best to share data in a useful way. At Springer Nature we are working on several initiatives to help facilitate the sharing of research data in a reusable way, with our overarching goal being to publish research that is robust and reproducible. I will talk about the effort that goes into our flagship data journal, Scientific Data, to facilitate best practices in publication and sharing of research data, and share some of our experiences publishing Challenge datasets. I will also describe some of the newer Research Data Services that are now available to help all researchers (not only Springer Nature authors) to share their data in a useful way.
Transparency and reproducibility in researchLouise Corti
Talk given at the ESS Summer School: An introduction to using big data in the social sciences, 20-24 July 2020, University of Essex, Colchester, UK.
In the morning we look at publishing and sharing data and the importance of research replication, code sharing, examining what methodological issues peer reviewers might look for in a published paper using big data. An increasing number of journals in the sciences and social sciences expect a high degree of transparency and knowing how best to publish high quality raw (or processed data), methodology and code is a useful skill. We show how ‘data papers’ help to elucidate how datasets were constructed, compiled and processed, and help to showcase the value of data beyond the original research.
Presentation slides on Open Science and research reproducibility. Presented by Gareth Knight (LSHTM Research Data Manager) on 18th September 2018, as part of an Open Science event for LSHTM Week 2018.
The challenge of sharing data well, how publishers can helpVarsha Khodiyar
Researchers, academic institutes and funders are increasingly recognizing the importance of data sharing for reproducible science. However, it is not always straightforward and clear to researchers as to how best to share data in a useful way. At Springer Nature we are working on several initiatives to help facilitate the sharing of research data in a reusable way, with our overarching goal being to publish research that is robust and reproducible. I will talk about the effort that goes into our flagship data journal, Scientific Data, to facilitate best practices in publication and sharing of research data, and share some of our experiences publishing Challenge datasets. I will also describe some of the newer Research Data Services that are now available to help all researchers (not only Springer Nature authors) to share their data in a useful way.
Transparency and reproducibility in researchLouise Corti
Talk given at the ESS Summer School: An introduction to using big data in the social sciences, 20-24 July 2020, University of Essex, Colchester, UK.
In the morning we look at publishing and sharing data and the importance of research replication, code sharing, examining what methodological issues peer reviewers might look for in a published paper using big data. An increasing number of journals in the sciences and social sciences expect a high degree of transparency and knowing how best to publish high quality raw (or processed data), methodology and code is a useful skill. We show how ‘data papers’ help to elucidate how datasets were constructed, compiled and processed, and help to showcase the value of data beyond the original research.
Presentation slides on Open Science and research reproducibility. Presented by Gareth Knight (LSHTM Research Data Manager) on 18th September 2018, as part of an Open Science event for LSHTM Week 2018.
Rachael LammeyCrossref Mary Hirsch DataCite
The underlying data created and/or reused and remixed for research is becoming as crucial as the resulting text-based output. This is your opportunity to dig into the what, the why, and the how of data publication, data citation, and data sharing. Workshop hosts will cover this topic from a range of perspectives. Let’s review the best practices and case studies in data citation and data publishing, add to our collective understanding of why this is so important, and contribute to the next steps in building solutions to improving infrastructure for research data
FAIR - Working Data - It's not just about FAIR publishing. Presented by John Morrissey from CSIRO at the C3DIS post conference workshop: Managed data – trusted research: an introduction to Research Data Management 31 may 2018 in Melbourne
How to get there from here- Research data Managment training. presented by Sue Cook, CSIRO, at the C3DIS post conference workshop; Managed data – trusted research: an introduction to Research Data Management in Melbourne 31st May 2018
Presentation by Ruth Wilson on Nature Publishing Group's Scientific Data journal given at the Now and Future of Data Publishing Symposium, 22 May 2013, Oxford, UK
Introduction to research data management. Presented by Natasha Simons at the C3DIS post conference workshop: Managed data – trusted research: an introduction to Research Data Management, Melbourne 31st may 2018
DataONE Education Module 01: Why Data Management?DataONE
Lesson 1 in a set of 10 created by DataONE on Best Practices fo Data Management. The full module can be downloaded from the DataONE.org website at: http://www.dataone.org/educaiton-modules. Released under a CC0 license, attribution and citation requested.
DataONE Education Module 03: Data Management PlanningDataONE
Lesson 3 in a set of 10 created by DataONE on Best Practices fo Data Management. The full module can be downloaded from the DataONE.org website at: http://www.dataone.org/educaiton-modules. Released under a CC0 license, attribution and citation requested.
Presentation given at the British Library Turing workshop on Software Citation, considering what lessons could be learned from the world of data citation
Identifying and tracking research resources using RRIDs: a practical approachdkNET
At this presentation, you will learn (1) Why you need to use Research Resource identifier (RRID) (2) What is Resource Identification Initiative (3) How dkNET.org supports RRID (4) What can you do with RRID
February 18 2015 NISO Virtual Conference Scientific Data Management: Caring for Your Institution and its Intellectual Wealth
Using data management plans as a research tool: an introduction to the DART Project
Amanda L. Whitmire, Ph.D., Assistant Professor, Data Management Specialist, Oregon State University Libraries & Press
Usages des réseaux sociaux académiques : enjeux et opportunités (2016)pascal aventurier
pour citer et télécharger le document . download or cite the document
Aventurier, P. (2016). Usages des réseaux sociaux académiques : enjeux et opportunités. Presented at E-RESEARCHER : Social medias, Open Access, Copyright, Libraries, Louvain-La-Neuve, BEL (2016-06-02 - 2016-06-02).
http://prodinra.inra.fr/record/355784
Rachael LammeyCrossref Mary Hirsch DataCite
The underlying data created and/or reused and remixed for research is becoming as crucial as the resulting text-based output. This is your opportunity to dig into the what, the why, and the how of data publication, data citation, and data sharing. Workshop hosts will cover this topic from a range of perspectives. Let’s review the best practices and case studies in data citation and data publishing, add to our collective understanding of why this is so important, and contribute to the next steps in building solutions to improving infrastructure for research data
FAIR - Working Data - It's not just about FAIR publishing. Presented by John Morrissey from CSIRO at the C3DIS post conference workshop: Managed data – trusted research: an introduction to Research Data Management 31 may 2018 in Melbourne
How to get there from here- Research data Managment training. presented by Sue Cook, CSIRO, at the C3DIS post conference workshop; Managed data – trusted research: an introduction to Research Data Management in Melbourne 31st May 2018
Presentation by Ruth Wilson on Nature Publishing Group's Scientific Data journal given at the Now and Future of Data Publishing Symposium, 22 May 2013, Oxford, UK
Introduction to research data management. Presented by Natasha Simons at the C3DIS post conference workshop: Managed data – trusted research: an introduction to Research Data Management, Melbourne 31st may 2018
DataONE Education Module 01: Why Data Management?DataONE
Lesson 1 in a set of 10 created by DataONE on Best Practices fo Data Management. The full module can be downloaded from the DataONE.org website at: http://www.dataone.org/educaiton-modules. Released under a CC0 license, attribution and citation requested.
DataONE Education Module 03: Data Management PlanningDataONE
Lesson 3 in a set of 10 created by DataONE on Best Practices fo Data Management. The full module can be downloaded from the DataONE.org website at: http://www.dataone.org/educaiton-modules. Released under a CC0 license, attribution and citation requested.
Presentation given at the British Library Turing workshop on Software Citation, considering what lessons could be learned from the world of data citation
Identifying and tracking research resources using RRIDs: a practical approachdkNET
At this presentation, you will learn (1) Why you need to use Research Resource identifier (RRID) (2) What is Resource Identification Initiative (3) How dkNET.org supports RRID (4) What can you do with RRID
February 18 2015 NISO Virtual Conference Scientific Data Management: Caring for Your Institution and its Intellectual Wealth
Using data management plans as a research tool: an introduction to the DART Project
Amanda L. Whitmire, Ph.D., Assistant Professor, Data Management Specialist, Oregon State University Libraries & Press
Usages des réseaux sociaux académiques : enjeux et opportunités (2016)pascal aventurier
pour citer et télécharger le document . download or cite the document
Aventurier, P. (2016). Usages des réseaux sociaux académiques : enjeux et opportunités. Presented at E-RESEARCHER : Social medias, Open Access, Copyright, Libraries, Louvain-La-Neuve, BEL (2016-06-02 - 2016-06-02).
http://prodinra.inra.fr/record/355784
1. Metamorfosis en la comunicación y evaluación científica
2. Estrategia general de comunicación: incrementando la visibilidad e impacto de un científico en la Web:
- DEPOSITAR documentos en los repositorios
- CONSTRUIR identidad bibliográfica digital: Perfil en GSC, RG…
- DIFUNDIR en redes sociales
3. ¿Cómo crear y mantener mi perfil en Google Scholar Citations?
4. ¿Cómo crear y mantener mi perfil en ResearchGate?
5. ¿Cómo crear mi identificador ORCID?
6. Otras redes académicas
Have you embarked on the processes of documenting and analyzing your academic program curricular data? These slides provide basic definitions of the processes of curriculum mapping (data gathering) and curriculum alignment (data analysis).
Preparing your data for sharing and publishingVarsha Khodiyar
Talk given as part of the MRC Cognition and Brain Sciences Unit Open Science Day on 20th November 2018 , University of Cambridge (https://www.eventbrite.co.uk/e/open-science-day-at-the-mrc-cbu-tickets-50363553745)
Presentation to IASSIST 2013, in the session Expanding Scholarship: Research Journals and Data Linkages. Describes PREPARDE workshop on repository accreditation for data publication and invites comments on guidelines.
Applying ocr to extract information : Text miningSaurabh Singh
Text Analysis (TA) is a process which takes unseen texts as input and produces fixed-format, unambiguous data as output.
This data may be used directly for display to users, or may be stored in a database or spreadsheet for later analysis, or may be used for indexing purposes in Information Retrieval (IR) applications.
International Workshop on Sharing, Citation and Publication of Scientific Data across Disciplines
Joint Support-Center for Data science Research (DS), ROIS
NIPR / NINJAL, Tachikawa, Tokyo, Japan, 5-7 December 2017.
Presentation on data sharing that outlines five layers that must be addressed to enable data to be located, obtained, access, understood and use, and cited.
Amy Friedlander's presentation to the PSP annual conference, February 2016. The topic is compliance with regulations concerning publishing the results of government-funded research.
The Dataverse repository framework (http://dataverse.org and http://dataverse.harvard.edu) helps Journals make the data accompanying scholarly articles accessible and citable.
More information at: http://scholar.harvard.edu/mercecrosas/presentations/dataverse-journals
dkNET Office Hours - "Are You Ready for 2023: New NIH Data Management and Sha...dkNET
For all proposals submitted on/after January 25 2023, NIH requires data sharing from all NIH-funded studies. Do you have appropriate data management practices and sharing plans in place to meet these requirements? Have questions or need some help? Join the dkNET office hours to learn about NIH’s policy (NOT-OD-21-013) and available resources that could help.
In our upcoming session on March 3, 2023, we are pleased to invite Dr. Jeffrey Grethe, dkNET co-PI and expert on Data Management and Sharing, Dr. Rebecca Rodriguez, Repository Program Director at NIDDK, Ms. Reaya Reuss, Chief of Staff to the Deputy Director at NIDDK, and the support team members from the NIDDK Central Repository. They will be available to answer any questions you may have.
*Previous Office Hours Slides and Recording: https://dknet.org/about/blog/2535
Upcoming Webinars Schedule: https://dknet.org/about/webinar
This presentation was provided by Maria Praetzellis of California Digital Library, during the NISO hot topic virtual conference "Effective Data Management," which was held on September 29, 2021.
Discussing Software Citation and related topics at Workshop on Data and Software Citation (June 6-7 at Harvard Medical School, http://www.software4data.com/#!nsf-workshop/jghgb)
This presentation was given by guest lecturer Dr. Hélène Draux of Digital Science Consultancy, during the fourth session of the NISO Spring training series "Working with Scholarly APIs." Session Four, Digital Science Dimensions, was moderated by Phill Jones of MoreBrains Cooperative and held on May 19, 2022.
ICIC 2017: Publication Analysis and Publication Strategy Dr. Haxel Consult
Dieter Küry (Novartis Pharma, Switzerland)
Using analytical methods are more and more replacing database searching in a knowledge manager's daily activities. In this presentation various facets of publication analysis will be presented and discussed. These new methods were applied for the analysis of publications in scientific journals and visuals were created to deduct publications strategies. On the technical side, the overall analysis process requires diverse tools for reference managing, text analysis and visualization. The impact on skills of the knowledge manager who moves from the expert for query languages to the expert for creation and maintaining of thesauri is also shown. Main benefit of the analytical methods compared to traditional database searching is the manifold use of results, which are easily adaptable to new requirements.
Data Publishing Models by Sünje Dallmeier-Tiessendatascienceiqss
Data Publishing is becoming an integral part of scholarly communication today. Thus, it is indispensable to understand how data publishing works across disciplines. Are there best practices others can learn from or even data publishing standards? How do they impact interoperability in the Open Science landscape? The presentation will look at a range of examples, and the main building blocks of data publishing today. The work has been conducted as part of the RDA Data Publishing Workflows group.
dkNET Office Hours - "Are You Ready for 2023: New NIH Data Management and Sha...dkNET
For all proposals submitted on/after January 25 2023, NIH will require the sharing of data from all NIH funded studies. Do you have appropriate data management practices and sharing plans in place to meet these requirements? Have questions or need some help? Join the dkNET office hours to learn about NIH’s policy (NOT-OD-21-013) and resources that could help.
*Previous Office Hours Slides and Recording: https://dknet.org/rin/research-data-management
Upcoming Webinars Schedule: https://dknet.org/about/webinar
Digital transformation to enable a FAIR approach for health data scienceVarsha Khodiyar
Invited talk for ConTech Pharma on 1st March 2022
Abstract
Health Data Research UK is the UK’s national institute for health data science, with a mission to unite the UK’s health data to enable discoveries that improve people’s lives. In this talk, Dr Varsha Khodiyar will outline how HDR UK is bringing together disparate health data from all four countries of the United Kingdom, creating the infrastructure to enable discovery of and access to health data, and the convening standards making bodies to improve data linkage and data reuse. Varsha will also discuss how HDR UK is moving beyond the traditional confines of FAIR data to also ensure that data sharing and data use is transparent and ‘fair’ for the patients and lay public who are the subjects of these datasets.
Lessons from the UK: Data access, patient trust & real-world impact with heal...Varsha Khodiyar
Slides supporting presentation given at the virtual Beilstein Open Science Symposium in October 2021.
Abstract:
Health Data Research UK’s mission is to unite the UK’s health data to enable discoveries that improve people’s lives. Our 20-year vision is for large scale data and advanced analytics to benefit every patient interaction, clinical trial, biomedical discovery and enhance public health. A key part of HDR UK’s vision is our data portal, the Innovation Gateway. The Gateway facilitates discovery of healthcare data and simplifies data request procedures across multiple data custodians. The Gateway contains metadata on a variety of datasets, including those related to COVID-19, cardiovascular, maternal health, emergency care, primary care, secondary care, acute care, palliative care, biobanks, research cohorts and deeply phenotyped patient cohorts.
From the outset HDR UK has sought the voices, views and experiences of patient and lay-public groups to ensure there is transparency and clear public benefit in the use of the UK’s health data. Patient and public involvement is key to making the Gateway accessible, transparent and to ensure public confidence in research access to health data. The importance of public outreach combined with providing research access to data is illustrated with HDR UK’s contribution to the UK’s coronavirus pandemic response. HDR UK was tasked by the UK’s Chief Scientific Office to build and facilitate the infrastructure to support the National Core Studies, providing key insights on the evolving situation to UK policy makers during the course of the pandemic.
In this talk, I will show how HDR UK is enabling open science by facilitating the discovery of health data, and simplifying the process of requesting access to multiple datasets. I’ll discuss HDR UK’s approach to embedding transparency on research data usage for patients and public, and summarise some of the key ways in which HDR UK has contributed to the coronavirus pandemic.
The information in this slide deck was presented at the Covid Crisis in India - Information & Appeal on Sunday 23rd May 2021.
If you find the information in this slide deck useful, please donate to https://justgiving.com/fundraising/covidcrisisinindia
Data citation and sharing during article publicationVarsha Khodiyar
Deck presented to CHORUS forum on 21st Jan 2021, as part of panel on Data Citations & Sharing (https://www.chorusaccess.org/events/chorus-forum-new-connections/)
What role can publishers play in the open data ecosystem?Varsha Khodiyar
Presentation at session 3 of the NIH workshop 'Role of Generalist Repositories to Enhance Data Discoverability and Reuse' on Feb 11th, at the NIH Main Campus.
New approaches to data management: supporting FAIR data sharing at Springer N...Varsha Khodiyar
Presentation given at Biocuration 2019 Session 5 (Data standards and ontologies: Making data FAIR)
Abstract:
Since 2016, academic publishers including Springer Nature, Elsevier and Taylor & Francis have been providing standard research data policies to journal authors, reflecting key aspects of the FAIR Principles’ practical applications: sharing data in repositories, using persistent identifiers and citing data appropriately. In spite of the rise of FAIR and good data management practice, recent surveys found that nearly 60% of researchers had never heard of the FAIR Principles, and 46% are not sure how to organise their data in a presentable and useful way. In this presentation we will analyse the results of a white paper which assessed the key challenges faced by researchers in sharing their data, and discuss current initiatives and approaches to support researchers to adopt good data sharing practice.
These include the roll-out of research data policies since 2016, as well as the launch of a Helpdesk service which has provided support to authors and allowed the research data team to capture more granular information on the challenges they face in sharing their data. We will also discuss the development of a third-party curation service which assists authors in depositing their data into appropriate repositories, and drafting data availability statements.
Finally we will assess the impacts of some of these interventions, including an analysis of data availability statements and an overview of the methods authors are currently using to share their data, and how these align with FAIR.
The value of data curation as part of the publishing processVarsha Khodiyar
Presentation given at Biocuration 2019 Session 5 (Interacting with the Research Community)
Abstract:Journals and publishers have an important role to play in the drive to increase the reproducibility of published science. Since its launch in 2014, the Nature Research journal Scientific Data has established a reputation for publishing data papers (‘Data Descriptors’) that are highly reusable, as evidenced by a strong citation record. One of the ways in which Scientific Data ensures maximum reusability of published data is via the in-house data curation workflow applied to every Data Descriptor. In 2017, Springer Nature launched its Research Data Support (RDS) service to provide data curation expertise to researchers publishing at other Springer Nature journals.
During curation at Scientific Data and RDS, our data editors familiarise themselves with the related manuscript and perform a thorough check of each data archive. This ensures the descriptions in the manuscript match the metadata and data at the data repositories. The curation process facilitates the identification of any discrepancies between the manuscript text and the information held at the data repository.
Over the last year, the curation team have been recording the types of discrepancies rectified as a direct result of our curation process. At Scientific Data approximately 10% of the discrepancies the team find are significant enough to potentially have warranted a formal correction had the issue had not been resolved prior to publication.
In this presentation we give an overview of our observed outcomes from embedding data curation within the publishing process. We describe of how we are monitoring the value of our curation work, and show examples of the types of discrepancy most commonly identified through curation at Scientific Data and RDS.
Facilitating good research data management practice as part of scholarly publ...Varsha Khodiyar
Presentation given to the SciDataCon #IDW2018 session: Democratising Data Publishing: A Global Perspective, on Tuesday 6th November 2018, Gaborone, Botswana
Practical challenges for researchers in data sharingVarsha Khodiyar
Presentation given at the Research Data Alliance Plenary 12 session: IG Open Questionnaire for Research Data Sharing Survey, on Tuesday 6th November 2018, Gaborone, Botswana
Update from Data policy standardisation and implementation IGVarsha Khodiyar
Update given to the Research Data Alliance Plenary 12 joint meeting session: WG FAIRSharing Registry and Data Policy Standardisation and Implementation IG, on Monday 5th November 2018, Gaborone, Botswana
Data Publishing and Institutional RepositoriesVarsha Khodiyar
Slides presented at the Force16 panel discussion on 18th April 2016 "Libraries united in opening new scholarly platforms" https://www.force11.org/meetings/force2016/program/agenda/concurrent-session-libraries-united-opening-new-scholarly
Presentation given at Open Science question and answer session hosted by the Institute for Quantitative Social Science (IQSS), and the Office for Scholarly Communication (OSC) at Harvard University, on July 16th 2014.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
The ASGCT Annual Meeting was packed with exciting progress in the field advan...
Workflows for Publishing Data; Scientific Data's experience as an early adopter
1. Workflows for Publishing Data
Varsha Khodiyar, PhD
Data Curation Editor, Scientific Data
Nature Publishing Group
varsha.khodiyar@nature.com
@varsha_khodiyar
@scientificdata
Scientific Data's experience as an early adopter
RDA P7, 1st to 3rd March 2016
2. Mandatory and recommended key components
of data publishing – WG results
Austin et al. in review. Report preprint doi:10.5281/zenodo.34542
Implemented by Scientific Data Under wider consideration
by Springer Nature
3. Implementation of required elements
• Data PID required to complete
manuscript submission
• Data Citation policy enforced by
editorial process
• Use of structured repositories which
capture subject-specific metadata
• Curation of discovery level metadata
(regardless of repository) by dedicated
Data Curation Editor
• Machine readable metadata aids
discovery
4. Additional elements - Context
4
• Data Descriptor designed to encourage
full documentation of data generation
• Articles analysing described data are
captured in machine readable metadata
(ISA format)
• Linked as associated publication to Data
Descriptor online
• Analysis articles published in Nature
Publishing Group journals link back to
Data Descriptor
• Software availability statement required
for previously unpublished software and
code
5. Additional elements - Quality
5
• Provision of manuscript (and metadata
templates) to help authors provide reuse level
metadata
• Dependant on repositories for curation by
domain experts
• Editorial Board selected based on expertise in
data generation/reuse in their field
• Ensure that peer reviewers can access data
easily and confidentially
• Encourage peer reviewers to view and comment
on the actual data as part of their assessment
• Editorial office regularly asked for advice on
data deposition and repository selection
6. • Data Descriptors aid visibility of data by
considering them as first class publications
• Data Descriptors discoverable via common
publication indices such as PubMed
• Discovery level machine readable metadata
(in ISA format) generated for every Data
Descriptor
• Currently trialling use of metadata for data
discovery (ISAexplorer)
• Open to suggestions for other uses of
Scientific Data’s machine readable metadata
Additional elements – Visibility / Accessibility
6
Editor's Notes
Published product in Scientific Data’s case is the data paper, which we call the Data Descriptor
Peer-reviewers are not expected to check every data file or "curate" the data. This is a task we feel is best performed by expert repositories, and with support from our in-house data curation support.
Rejections after review remain rare, but on at least a few occasions peer-reviewers have identified issues within the actual data files that ultimately led to rejection (e.g. evidence of data contamination or other serious quality issues).
We believe that making the data easily available to peer reviewers can actually save them time in these cases, because they do not need to "play detective" -- expects can often make an assessment more rapidly and more accurately when presented with the real data.
Data Descriptors are discoverable on nature.com, visited by millions, and via common publication indices (PubMed, MEDLINE, Google Scholar -- Scopus and Thomson Reuters to come soon). This also makes them amenable to tracking by traditional metrics, like citation.
Scientific Data also delivers progressively FAIR metadata (Findable, Accessible, Interoperable and Reusable)