This document provides an overview of West Nile virus (WNV), including its history, transmission, symptoms, and prevention. It notes that WNV is a flavivirus transmitted by mosquitoes that was first identified in Uganda in 1937 and appeared in New York City in 1999. The document outlines the virus's pathology and seasonal activity, noting it replicates in mosquitoes and birds but can cause mild to severe illness in humans. It recommends preventative measures like avoiding mosquito bites during dawn and dusk to reduce risk of infection.