This document discusses vitamin E, including its structure, sources, roles in the body, health benefits, and deficiencies. Some key points: - Vitamin E plays a role in maintaining health of tissues and can protect lungs from pollution. Major sources include sunflower seeds, almonds, and avocados. - It has benefits such as reducing risks of cataracts, diabetes, Parkinson's disease, and respiratory infections. High doses may improve insulin resistance and blood sugar control. - Deficiency can occur in premature infants and those with fat malabsorption issues. Symptoms include anemia. Overdosing on high levels may cause side effects like nausea and interfere with absorption of vitamins A and K.

1. • What is Vitamin
?

2. INTRODUCTION
Vitamins (English: vital amine, vitamins) are a
group of small-molecular-weight organic
compound which has a vital function in the
metabolism of every organism, which can not
be produced by the body. The name is derived
from the combination of the Latin word vita
which means "life" and amine(amine) that
refers to an organic group that has a nitrogen
atom (N)

3. •Vitamins have a specific role
in the body and can also
provide health benefits. If
levels of these compounds is
insufficient, the body can
suffer a disease.
•There are 13 types
of vitamins needed by the
body to be able to grow and
develop properly.

4. VITAMIN “E”
•Scientific name of vitamin E is
Tocopherol.
•Vitamin E plays a role in maintaining the
health of various tissues in the body,
ranging from skin tissue, eyes, red blood
cells to the liver. In addition,
this vitamin can also protect human lungs
from air pollution. Vitamin E is found in
fish, chicken, egg yolks, yeast, and
oilseeds.

5. CHEMISTRYOF VITAMIN“E”

6. STRUCTURE

7. STRUCTURE

8. Sources of vitamin

9. SunflowerSeeds
• One ounce of dry-
roasted sunflower
seeds delivers 7.4 mg
of vitamin E.

10. • ALMONDS (7.3 mg of
vitamin E per ounce)
• HAZELNUTS (4.3 mg of
vitamin E per ounce)
• PEANUTS (2.2 mg of
vitamin E per ounce)
• PINENUTS(One ounce of
pine nuts contains 2.6
mg of vitamin E)

11. Turnip Greens
• A half cup has 2.9 mg
of vitamin E

12. TOMATOES
• A quarter cup of
tomato paste has
2.8 mg of
vitamin E.

13. AVOCADO
• Half an avocado
has 2.1 mg of
vitamin E and
161 calories.

14. Pharmacological properties
1. Prevention of oxidative stress
2. Supporting healthy skin
3. Vitamin E inhibits platelet aggregation
4. Vitamin E may be involved in signal transduction in
neuronal cells

15. Therapeutic indications
• Angina
pectoris
• Acne
• Alzheimer’s
disease
• Cancer
• Cataracts
• Diabetes
• Psoriasis
• Parkinson’s disease
• Respiratory infection
etc.

16. CATARACTS
•Cataract is caused by metabolic by-products
called free radical
•vitamin E supplements can reduce the risk of
cataracts.
•It is powerful antioxidant helps to prevent
cataract

17. Diabetes
1:High does vitamin E appeared to temporarily
improve insulin resistance
2:Vitamin E has also been shown to help some
diabetics gain better control over their blood sugar

18. Parkinson’s disease
•High dose vitamin E dietary supplementation or
parenteral vitamin E administration (e.g. vitamin E
succinate) may serve as a successful therapeutic strategy
for the prevention or treatment of PD (by enriching
substantia nigra mito with protective levels of T).

19. Respiratory Infections
• Vitamin E supplementation has been shown to improve
immune response in the elderly.
• Supplementation with 200 IU per day E significantly
reduced the incidence of common colds in elderly nursing
home residents by 20%
•It decrease the risk of acquiring a cold by 21%

20. deficiency
• In humans, deficiency of vitamin E is seen in
Premature infants
• Transfer of vitamin E from maternal blood occur
during last few weeks of pregnancy
• Premature infants will have vitamin E deficiency
• Impaired absorption: seen in conditions such as
• Abetalipoproteinemia (fat malabsorption)
• Obstructive jaundice
• Intestinal diseases such as celiac sprue

21. • Genetic vitamin E deficiency:
it is caused by lack of protein that normally
transports α–tocopherol from hepatocytes to
VLDL
• Clinical features:
Hemolytic anemia or macrocytic anemia seen in
premature infants
In adults, increased susceptibility of erythrocytes
for hemolysis under oxidative stress
Muscles weakness and proteinuria is seen.

22. SIDE EFFECTS/ADVERSE EFFECT
• Taking vitamin E supplements for up to 4 months at doses of 530mg or
800 IU (35 times that current RDA) had no negative side-effect on general
health,
• Body weight
• Level of body proteins lipids level
• liver or kidney function
• Thyroid hormones
• Amount or kinds of blood cells
• And bleeding time over doses may cause nausea, vomiting, diarrheoa
• Vitamin E products in excess of 1200 IU daily may interfere with
absorption and metabolism of vitamins A and k but one can get benefits
with much lower levels of vitamin.
• Individuals who are vitamin K (people who are on blood thinners) deficient
should not take alpha-tocopherol supplements without close medical
supervision because of the increased risk of hemorrhage

23. Contraindications
• Contraindications have not yet been
identified.

24. Interactions
1. Vitamin E may increase the anticoagulant
effect of warfarin.
2. may decrease the benefits of atorvastatin
therapy.
3. Plasma levels of vitamin E may be lowered by
anticonvulsants.

25. PRODUCTS
VITAMINE-GEL:
• An oxidant that repairs and rebuild tissues
• Help to reduce inflammation and damage to
hair follicle.
• Encourages hair growth
BRANDS:
• Vitamin e-gel of desnert brand
• Vitamin E-gel of wallgreens

26. VITAMINE-OIL:
• It acts as a moisture to your skin.
• It is used as an antiaging products.
• Any kind of scar mainly surgery scars can be
healed
• It hydrates the dehydrated skin.
BRAND NAMES:
• Bella-Terra vitamin E-oil
• Sun-Down vitamin E-oil

27. NATUREMADE ‘E’ SUPPLIMENT
• Helps to maintain a healthy heart
• Made up of d-alpha tocopherol the most
active in terms of antioxidant activity.
• A product by USP (united states
pharmacopeia)

28. Nutrient Interactions
1. Vitamin C
2. Glutathione
3. Selenium
4. Vitamin B3

29. Deficiency syndrome
1.digestive system problems
2.peripheral neuropathy

30. Hypervitaminosis
1. Intestinal cramps
2. Diarrhea
3. Fatigue
4. Double vision
5. Muscle weakness

31. Sources
1. http://www.whfoods.com/genpage.php?tname=nutrient&dbid=111
2. http://painandbrainhealingcenter.com/vitaminearticle.html#.UnnXhHCBlfB
3. http://news.vanderbilt.edu/2012/07/high-consumption-of-vitamin-e-may-lower-
liver-cancer-risk/
4. http://www.antioxidantsdetective.com/vitamin-e-facts.html
5. http://www.webmd.com/vitamins-supplements/ingredientmono-954-
VITAMIN%20E.aspx?activeIngredientId=954&activeIngredientName=VITA
MIN%20E

32. Thank you.