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Vitamin C and the Common Cold Written by: Corrie Cox DTC 422
Background  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Sources  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Deficiency ,[object Object],[object Object],[object Object],[object Object]
RDA and Overconsumption ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vitamin C & Common Cold ,[object Object],[object Object],[object Object],[object Object],[object Object]
Vitamin C & Common Cold ,[object Object],[object Object],[object Object]
Media Report ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Media Report ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence  ,[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scientific Evidence ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object]
References ,[object Object],[object Object],[object Object],[object Object]
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Vitamin c and the common cold

  • 1. Vitamin C and the Common Cold Written by: Corrie Cox DTC 422
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Editor's Notes

  1. Humans are not able to synthesize vitamin C due to lack of gulonolactone oxidase which is that last enzyme in the vitamin C synthetic pathway (1). The L-isomer is biologically active in humans (1). Other animals that cannot synthesize vitamin C include: primates, fruit bats, guinea pigs, and some birds (1).
  2. British sailors often died from scurvy on the sea, due to a deficiency in vitamin C (1).
  3. During a cold the most common source of vitamin C is orange juice, in addition to it’s convenience it can also help sooth the throat if chilled (2). Complementary alternative medicines are defined as a group of medical and health care practices that are not considered to be apart of conventional medicine (2). Some research exists in regards to these therapies, but questions whether they are safe/effective still remain (2).
  4. Article states that taking vitamin C on a daily basis will not help in the prevention of a cold; and for the average person, purchasing supplements is an unnecessary expense (3). In addition, the role that vitamin C has in the body is to protect cells and absorb iron from food (3). The article looked at research from a meta-analysis which studied the effects of taking 200mg of vitamin C a day; in addition, they used an analysis about vitamin C and the common cold from the Cochrane Library (3).
  5. In 2004, Douglas et al. analyzed six out of thirty trials (2).
  6. Study conducted by Bruce Barrett et al. The study interviewed subjects through questionnaires by means of the telephone or in person to see if they currently had a cold or symptoms of a cold (4). Upon selection, 253 rationally diverse (in terms of race, education, and income) participants were than randomly presented with one of four scenarios (all scenarios had no risk involved) (4).
  7. Study conducted by Bruce Barrett et al. Two classes of medical professionals were given questionnaires, common cold researchers (experts) and practicing family physicians (5). Results showed that both experts and family physicians felt that cold remedies do not decrease the duration of a cold (5). Opinions varied regarding the severity of reduction, with decongestants being the most popular method, with alternative methods (which includes vitamin C) and conventional methods were seen as equally favorable (5).
  8. Study conducted by Wintergerst et al. When the body is under stress or is infected there is a rapid decline in the vitamin C concentration in plasma and leukocytes (6). The role that vitamin C plays is that it maintains the redox integrity of the cells and protects them against reactive oxygen species during respiratory bursts (6). Both nutrients play an important role in immune function, resistance of infection, and reduction of risk and severity of diseases (6).
  9. Study conducted by Audera et al. Four intervention arms: vitamin C at daily doses of 0.03g (placebo), 1 g, 3g, or 3g with additives (Bio-C) which was taken at start of a cold and for the following two days (7). When the patients felt they were staring a cold they were instructed to take their medication and record how they felt, doctor visits, and if any other medications were taken (7)
  10. Written by Hickey et al. in response to the Cochrane Review written by Douglas et al. Hickey et al. states that the review excludes pharmacokinetic data that cancels out the conclusion that vitamin C is an ineffective treatment for the common cold (8).