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Centrifugation is a process that involves the use of the centrifugal
force for the separation of mixtures
Principle of centrifugationPrinciple of centrifugation
If a particle (mass = m kg) spins in a centrifuge
(radius r, m) at a velocity (v, m s-1
) then the centrifugal
force (F, N) acting on the particle equals m v2
/r.
The same particle experiences gravitational force
(G, Newton) = m g (where g = acceleration due to gravity)
F = m v2
/r
F= centrifugal force
Centrifugal force (F)Centrifugal force (F)
Centrifugal effect (C)Centrifugal effect (C)
The centrifugal effect (C) is the ratio of these
two forces, so C = F/G, i.e. C indicates how much
greater F is than G
Centrifugal effect, C=
Force acting in radial direction
Gravitational force
Consider a body of mass ‘m” kg rotating in a circular path
of radius “r” at a velocity of “v”
Centrifugal force =f= mv2
/r
Same body is experiencing gravitational force, it can be expressed
as “G= mg , where g = acceleration due to gravity, and m= mass
Centrifugal effect (C) = F/G
= mv2
/mgr
(v = 2 π r n )
c = (2π r n)2
/ g r
= 4 π2
rn2
/ g
(d= r/2)
= 2 π2
d n2
/ g
(g = 9.807)
C = 2.013 d n2
Centrifugal effect, C= 2.013 n2
dCentrifugal effect, C= 2.013 n2
d
Classification of centrifugesClassification of centrifuges
There are two main types of centrifuge used to
achieve separation on an industrial scale,
(1)Filtration centrifuge: Those using perforated
baskets, which perform a filtration-type operation
(work like a spin-dryer) and
(2) Sedimentation centrifuge : Those with a solid
walled vessel, where particles sediment towards
the wall under the influence of the centrifugal force
There are two main types of centrifuge used to
achieve separation on an industrial scale,
(1)Filtration centrifuge: Those using perforated
baskets, which perform a filtration-type operation
(work like a spin-dryer) and
(2) Sedimentation centrifuge : Those with a solid
walled vessel, where particles sediment towards
the wall under the influence of the centrifugal force
Perforated-basket centrifuges
(centrifugal filters)
Perforated-basket centrifuges
(centrifugal filters)
Fig. Perforated basket centrifuge
Tubular-bowl centrifuges
(centrifugal sedimenters)
Tubular-bowl centrifuges
(centrifugal sedimenters)
Fig: Tubular-bowl centrifuge
Continuous centrifugeContinuous centrifuge
unit operation , centrifugation

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unit operation , centrifugation

  • 1.
  • 2. Centrifugation is a process that involves the use of the centrifugal force for the separation of mixtures
  • 4.
  • 5. If a particle (mass = m kg) spins in a centrifuge (radius r, m) at a velocity (v, m s-1 ) then the centrifugal force (F, N) acting on the particle equals m v2 /r. The same particle experiences gravitational force (G, Newton) = m g (where g = acceleration due to gravity) F = m v2 /r F= centrifugal force Centrifugal force (F)Centrifugal force (F)
  • 6. Centrifugal effect (C)Centrifugal effect (C) The centrifugal effect (C) is the ratio of these two forces, so C = F/G, i.e. C indicates how much greater F is than G Centrifugal effect, C= Force acting in radial direction Gravitational force
  • 7. Consider a body of mass ‘m” kg rotating in a circular path of radius “r” at a velocity of “v” Centrifugal force =f= mv2 /r Same body is experiencing gravitational force, it can be expressed as “G= mg , where g = acceleration due to gravity, and m= mass Centrifugal effect (C) = F/G = mv2 /mgr (v = 2 π r n ) c = (2π r n)2 / g r = 4 π2 rn2 / g (d= r/2) = 2 π2 d n2 / g (g = 9.807) C = 2.013 d n2
  • 8. Centrifugal effect, C= 2.013 n2 dCentrifugal effect, C= 2.013 n2 d
  • 9. Classification of centrifugesClassification of centrifuges There are two main types of centrifuge used to achieve separation on an industrial scale, (1)Filtration centrifuge: Those using perforated baskets, which perform a filtration-type operation (work like a spin-dryer) and (2) Sedimentation centrifuge : Those with a solid walled vessel, where particles sediment towards the wall under the influence of the centrifugal force There are two main types of centrifuge used to achieve separation on an industrial scale, (1)Filtration centrifuge: Those using perforated baskets, which perform a filtration-type operation (work like a spin-dryer) and (2) Sedimentation centrifuge : Those with a solid walled vessel, where particles sediment towards the wall under the influence of the centrifugal force
  • 12.
  • 15.