Subroutines and functions allow programmers to organize code into reusable blocks. Subroutines contain code that is executed when called but do not return a value, while functions contain code that is executed and returns a value. Both can be called with or without parameters to make them more flexible. To call a subroutine, use the Call statement or just the subroutine name. To call a function, assign its return value to a variable using the function name. The key difference is that functions return a value that can be assigned to a variable, while subroutines do not.