This presentation is all about the systemic administration of fluorides ,as it is an easier way for the administration of fluorides to prevent dental caries and tooth decay.the aim is to explain the advantages of systemic fluoride ,their present status in India and in other countries and to create awareness among population.Also raising an issue that how these methods of systemic fluoride administration can be improved so that there is better prevention of decay problems
This presentation is all about the systemic administration of fluorides ,as it is an easier way for the administration of fluorides to prevent dental caries and tooth decay.the aim is to explain the advantages of systemic fluoride ,their present status in India and in other countries and to create awareness among population.Also raising an issue that how these methods of systemic fluoride administration can be improved so that there is better prevention of decay problems
A broad idea about Esthetic Crown objectives and their Indications along side with the drawbacks of SSC also the Classification of esthetic crowns plus the Pros and cons of each esthetic crown.
Vital pulp therapy plays important role in preserving tooth and tooth vitality in both primary and permanent teeth.
Direct pulp capping, indirect pulp capping, pulpotomy has been covered in this presentation. All materials possibly useful in vital pulp therapy as well as recent advances have been included with all the evidences.
A broad idea about Esthetic Crown objectives and their Indications along side with the drawbacks of SSC also the Classification of esthetic crowns plus the Pros and cons of each esthetic crown.
Vital pulp therapy plays important role in preserving tooth and tooth vitality in both primary and permanent teeth.
Direct pulp capping, indirect pulp capping, pulpotomy has been covered in this presentation. All materials possibly useful in vital pulp therapy as well as recent advances have been included with all the evidences.
This is a presentation prepared by my graduate students of Natural Resources Management, Biodiversity Conservation subject, at Nepal Engineering College of Pokhara University. All "students" are highly experienced foresters with 10-20 years of experience, so the material is firmly grounded in Nepali practice!
لا أحد يجادل حول ضرورة توحيد جهود العاملين بالمنظمات حول استراتيجية واضحة وقوية ومحفزة ، إن تحديد رؤية استراتيجية وترجمتها في مخطط استراتيجي معناه توفير شرط أساسي وحاسم لاستشراف المستقبل ، وتحفيز الجهود ، وترشيد الوسائل والإمكانات ، إن وضع مخطط استراتيجي هو أيضاً فرصة لحوار تأسيسي بناء وخيالي بين مختلف العاملين بالمنظمة .
The Ultimate Guide to Creating Visually Appealing ContentNeil Patel
From videos to infographics, I’m constantly leveraging visual media.
Can you guess why?
It’s because these visual content pieces are generating more backlinks than any other form of content I publish, which—in the long run—helps increase my search engine rankings and overall readership numbers.
So, how do you create these visual masterpieces? Well, this infographic should help you.
What we carry with us in our everyday lives and interactions is just as important for our success as our technical skills and achievements.
This is what I carry with me. What do YOU carry?
Slides designed and produced with Haiku Deck for iPad. Set your story free with Haiku Deck at http://www.haikudeck.com/
You can learn more about Jonathon Colman at http://www.jonathoncolman.org/
learning objectives
Introduction
History Of Water Fluoridation
How Does Fluoride Act In Dental Caries Prevention?
Goals Of F Administration
Fluoride Administration
Appropriate Levels Of Fluoride in Drinking Water
Methods of water fluoridation
--------------------------------------------------------------------
Efficacy Of topical fluorides
Range Of therapeutic fluoride concentrations used to prevent caries
Recommended doses
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
2.
Member of the halogen family with relative atomic
weight 19
Atomic number – 9
Fluorine derived from Latin term ‘fluore’ meaning,
“to flow”
Occurs in combined form such as Fluorspar[fluorite
CaF2], Fluorapatite[Ca10F2(PO4)6], Cryolite[NaAlF6]
The element Fluorine
3. Dr. Fredrick McKay (Colorado Springs, Colorado, USA) –
1901 saw the stains on the teeth of his pts. The local
inhabitants called it the ‘Colorado stain’.
He called the stain “mottled enamel”.
First systemic endeavour to investigate the lesion was
made by the Colorado springs dental society in 1902
He approached one of the America’s foremost authorities
on dental enamel, Dr. Greene Vardiman Black.
Black asked him to send the mottled teeth for
examination after that he agreed to attend the Colorado
state dental association meeting in 1909, and promised to
spend some weeks in Colorado springs before the
meeting.
HISTORY
4.
In 1931 U.S. govt appointed Dr. Trendly H Dean to
continue the work of Mckay.
Dean conducted survey in 22 cities in USA.
5.
Canned fish products – Salmon & Sardin – 20-
40mg/kg
Fish protein concentrates – 370mg/kg
Jowar, banana, potatoes
Rock salt (40-200ppm)
Dried tea leaves (100-400ppm)
Sources of fluoride
6.
Increase enamel resistance (or) reduction in enamel
solubility
Increased rate of posteruptive maturation
Remineralization of incipient lesions
Interference with plaque microorganisms
Modification with tooth morphology
Mechanism of action of
fluorides
7.
Fluoride inhibits demineralization in several ways,
By reducing bacterial acid production
By reducing the equilibrium solubility of apatite
By the fluoridation of apatite crystal surfaces
reducing the dissolution rate whether or not there is
reduced solubilty of the bulk material
Increased enamel resistance/Reduction
in enamel solubility
8.
Importance of fluoride in maturation process lies in
its ability to increase the rate of mineralization of
hypomineralized areas
Posteruptive maturation involves deposition of
minerals into hypomineralized areas
Increased rate posteruptive
maturation
9.
Fluoride plays critical role in the reducing of dental
caries by enhancing remineralization.
Remineralization, the deposition of minerals into
previously damaged areas of the tooth is a process
that results in enamel solubility
Remineralization of incipient
lesions
10.
Fluoride has been known to inhibit bacterial
enzymatic processes involved in carbohydrate
metabolism
In high conc., fluoride is bactericidal. Helps reduce
plaque
In lower conc., fluoride is bacteriostatic. Helps
control the growth of bacteria without destroying
them.
Interferance with
microorganisms
11.
If fluoride is ingested during the tooth development,
there is some evidence to suggest the fromation of a
more caries resistant tooth slightly smaller with
shallow fissures.
Modification in tooth
morphology
13. TOPICAL FLUORIDES SYSTEMIC FLUORIDES
These are placed directly
on the teeth
Some preparations
provide high or low
concentrations of fluoride
over a short period of
time
These circulate through
the blood stream and are
incorporated into
developing teeth
They provide a low
concentration of fluoride
over a long period of
time
14.
TOPICAL FLUORIDES
By the definition the term “topically applied fluorides”
is used to describe those delivery systems which
provide fluoride for a local chemical reaction to
exposed surfaces of the erupted dentition.
15. INDICATIONS
Caries active individuals
Children shortly after period of tooth eruption
Those who take medication that decrease salivary
flow or have received radiation to head and neck
After periodontal surgery when roots of teeth have
been exposed
Patients with fixed or removable prosthesis and after
placement or replacement of restorations
Patients with an eating disorder or who are
undergoing a change in lifestyle which may affect
eating or oral hygiene habits conductive to good oral
health
Mentally and physically challenged individuals
16. TOPICAL FLUORIDE PRODUCTS ARE
DIVIDED INTO 2 CATEGORIES
(A) Professionally applied
Introduced by Bibby in 1942
Dispensed by dental professionals in the dental office
and usually involve the use of high fluoride
concentration products ranging from 5000-19000 ppm
which is equivalent to 5-9 mg F/ml
(B) Self applied
Include fluoride dentifrices, mouth rinses & gels
Are low fluoride concentration products ranging from
200-1000ppm or 0.2-1 mgF/ml.
17. RATIONALE FOR USING TOPICAL
FLUORIDE AGENTS
To speed up the rate and increase the
concentration of fluoride acquisition above
the level which occurs naturally
The initial caries lesion characterized by a
white spot is porous and accumulates
fluoride at a much higher concentration than
adjacent sound enamel hence periodic
application of fluoride would enable
vulnerable enamel sites that are partially
demineralized to accumulate fluoride
18. PROFESSIONALLY APPLIED
FLUORIDES
FLUORIDE VEHICLES
AQUEOUS SOLUTIONS AND GELS
Gel adheres to the tooth surface for a considerable
amount of time and eliminates the continuous wetting
of enamel surfaces when solutions are used
2 or 4 quadrants can be treated simultaneously when
trays are used for gel application which results in
substantial saving of time
Thyxotrophic solutions are not gels but have high
viscosity under storage conditions and become fluid
under high stress
Thyxotrophic solutions are more stable at lower pH
and do not run off the tray as readily as conventional
gels
20. FLUORIDATED PROPHYLACTIC PASTES
If prophylaxis pastes
containing fluoride are
used, the lost fluoride is
replenished & there is a
significant gain in the
concentration of
fluoride.
21. FOAM
Developed to minimize the risk of fluoride over
dosage as well as to maintain the efficacy of topical
fluoride treatment.
ADVANTAGES:
Its lighter than a conventional gel & therefore only a
small amount of agent is needed for topical
application
The surfactant has cleansing action by lowering
surface tension, this facilitates the penetration of
material into interproximal surfaces.
It doesn’t require suctioning so it offers advantages for
home use
23. FLUORIDE VARNISH
It was first developed by Schimdt in Europe in 1964
Increasing the time of contact between enamel surface
& topical fluoride agents favors the deposition of
fluorapatite & fluorhydroxyapatite.
Technique:
After prophylaxis teeth are dried but not isolated with
cotton rolls since varnish sticks to cotton
Total of 0.3-0.5 ml of varnish is required to cover full
dentition
Application is done first done on lower arch then
upper, using single tufted small brush, starting with
proximal surfaces
Patient is asked to sit with mouth open for 4 min to let
Duraphat set on teeth
25. Patient is asked to not rinse or drink anything for one hour
and advised liquid diet till next morning
DURAPHAT:
It is a first fluoride varnish developed in germany, viscous
yellow material, containing 22,600 ppm fluoride as sodium
fluoride in a neutral colophonium base.
FLUORPROTECTOR:
It is a clear polyurethane based product containing 7000
ppm fluoride from difluorosilane.
It is dispensed in 1ml ampoules each ampoule containing
6.21mg of fluoride.
CAREX:
It has low fluoride concentration than duraphat & has
equal efficacy to that of duraphat as caries preventive
agent
26. TOPICAL FLUORIDES USED IN PREVENTIVE
DENTISTRY:
SODIUM FLUORIDE
STANNOUS FLUORIDE
ACIDULATED PHOSPHATE FLUORIDE
AMINE FLUORIDE
1) NEUTRAL SODIUM FLUORIDE (NaF)
Fluoride concentration - 9200ppm
A minimum of four applications with a 2% NaF
solution gives a caries reduction of about 30%
METHOD OF PREPARATION
It is prepared by dissolving 20 gms of NaF powder in
1L of distilled water in a plastic bottle
27. TECHNIQUE - KNUTSON’S TECHNIQUE
At the initial appointment teeth are cleaned with pumice slurry &
then isolated with cotton rolls & dried with compressed air.
Using cotton-tipped applicator sticks ,the 2% NaF is painted on air
dried teeth so that all tooth surfaces are visibly wet. The solution is
allowed to dry for 3-4 min.
This procedure is repeated for each of the isolated segments until all
the teeth are treated.
A 2nd, 3rd and 4th fluoride application, each not preceded by a
prophylaxis, is scheduled at intervals of approximately one week;
The four-visit procedure is recommended for ages 3, 7, 11 and 13
years, coinciding with the eruption of different groups of primary
and permanent teeth.
28. MECHANISM OF ACTION :
When NaF is applied on tooth surface it reacts with
hydroxyapatite crystals in enamel to form Calcium fluoride
(CaF2) which is the dominant product of the reaction
As thick layer of CaF2 forms, it interferes with further diffusion
of fluoride from the topical fluoride solution to react with
hydroxyapatite and blocks further entry of fluoride ions. This
sudden stop of the entry of fluoride is termed as ‘chocking off
effect’
CaF2 acts as a reservoir and fluoride slowly leeches out of it
The CaF2 formed reacts with hydroxyapatite fluoridated
hydroxyapatite increases the concentration of fluoride on
enamel surface prevents caries
29. ADVANTAGES :
It is relatively stable when kept in a plastic container;
The taste is well accepted by patients;
The solution is non-irritating to the gingiva;
It does not cause discoloration of tooth structure;
The series of treatments must be repeated only 4 times
in the general age range of 3 to 13, rather than at
annual or semiannual intervals.
DISADVANTAGES:
The major disadvantage of the use of sodium fluoride
is that the patient must make 4 visits to the dentist
within a relatively short period of time.
30. 2) STANNOUS FLUORIDE (SnF2)
Fluoride concentration-19500ppm
Stannous fluoride has been used at 8% and 10%
concentrations
METHOD OF PREPARATION:
Solutions of stannous fluoride are not stable. Soon after
mixing they become cloudy due to the formation of tin
hydroxide.
A fresh solution of stannous fluoride be prepared for each
patient.
To prepare 8% stannous fluoride solution, the content of
one capsule which is 0.8 grams (‘0’ No. of gelation capsule)
is dissolved in 10 ml of distilled water in a plastic container.
31. TECHNIQUE - MUHLER’S TECHNIQUE
Each tooth surface is cleaned with pumice or other
dental cleaning agent for 5 to 10 seconds;
Unwaxed dental floss is passed between the
interproximal areas;
Teeth are isolated and dried with air;
Stannous fluoride is applied using the paint-on
technique and the solution is kept for 4 minutes.
Repeat applications are made every 6 months or more
frequently if the patient is susceptible to caries.
32. MECHANISM OF ACTION:
When SnF2 is applied in low concentration
tinhydroxyapatite, which gets dissolved in oral tissues
At very high concentration Ca trifluorostannate forms
along with tin tri-fluorophosphate
Tin trifluorophosphate is responsible for making the
tooth structure more stable and less susceptible to
decay
CaF2 is the end product both at low and high
concentration which reacts with hydroxyapatite and a
small fraction of fluorhydroxyapatite also gets formed
33. ADVANTAGES :
Using an 8% stannous fluoride solution at 6 to 12 months
intervals conforms to the practicing dentist’s usual patient –
recall system;
Administrative difficulties are avoided.
DISADVANTAGES :
In aqueous solution the material is not stable;
8% solution is quite astringent and disagreeable in taste, its
application is unpleasant;
The solution occasionally causes a reversible tissue
irritation manifested by gingival blanching;
Causes pigmentation of teeth which has a characteristic
light brown colour
34. 3) ACIDULATED PHOSPHATE FLUORIDE (APF)
Fluoride concentration-12300 ppm
METHOD OF PREPARATION
An aqueous solution is acidulated phosphate fluoride
is prepared by dissolving 20 grams of sodium fluoride
in 1 liter of 0.1 M phosphoric acid and to this is added
50% hydrofluoric acid to adjust the pH at 3.0 and
fluoride ion concentration at 1.23%. It is also called as
Brudevold’s solution
For the preparation of acidulated phosphate fluoride
gel, a gelling agent methylcellulose or hydroxyethyl
cellulose is added to the solution.
35. TECHNIQUE
APF is recommended for application at 6 or 12 months
interval
Oral prophylaxis is done
Teeth to be treated are completely isolated and
thoroughly dried with air
Application of gel is done using trays; disposable
foam lined trays are preferred
It is reapplied every 15-30sec so as to keep the teeth
moist with the fluoride solution throughout the four
min period
The patient is instructed to eat, drink or rinse his
mouth for atleast 30 min
37. MECHANISM OF ACTION
When APF is applied to teeth it initially leads to
dehydration and shrinkage in the vol of hydroxyapatite
crystals which on hydrolysis forms an intermediate
product called Dicalcium phosphate dihydrate(DCPD)
DCPD is highly reactive and starts forming immediately
after APF is applied
Fluoride penetrates into the crystals more deeply through
the openings produced by shrinkage and forms fluorapatite
For the conversion of whole DCPD formed into
fluorapatite, a deeper penetration and continuous supply of
fluoride is required. Because of this reason APF is applied
every 30 sec and the teeth have to be kept wet for 4 min
38. ADVANTAGES
Requires only 2 application in a year;
The gel preparation can be self applied and thus the
cost of application also gets reduced;
It has the ability to deposit fluoride in enamel to a
deeper depth;
DISADVANTAGES :
Practical difficulties like the teeth should be kept wet
for for 4 minutes;
It is acidic, sour and bitter in taste;
It cannot be stored in glass containers.
39. 4) AMINE FLUORIDE
They are cariostatic agents
Some of them are surface active agents i.e. they have
an affinity for enamel and thus will hold the fluoride
for a longer time against the tooth
They also have anti bacterial properties. Reduced
plaque formation and anti glycolytic activity is also
reported with these compounds
Amine fluorides have been tested in dentifrices,
mouthrinses and topical gels where they are either
brushed on teeth or applied with a tray but it is not
known if they are superior to the other currently
available fluoride agents
40. Characteristics Sodium fluoride Stannous
fluoride
Apf
Percentage 2% 8% 1.23%
Fluoride
concentration
(ppm)
9200 19500 12300
ph neutral 2.4-2.8 3.0
Frequency of
application
4 at weekly
intervals 3,7,11 &
13 yrs
biannually biannually
Adverse effects no Tooth
pigmentation
Gingival
irritation
no
Caries reduction 30% 32% 28%
41. RECOMMENDATIONS FOR TOPICAL
APPLICATION
No more than 2 g of gel per tray or approximately
40% of tray capacity.
Pt. may have the need to swallow during the 4min
procedure, saliva ejector is recommended.
After the procedure the pt. be instructed to
expectorate thorougly for from 30sec to 1min.
42. SELF APPLIED TOPICAL
FLUORIDES
Dentifrices
Mouth rinses
Gels
DENTIFRICES
The first clinical trial of fluoride dentifrice was
initiated by Bibby in 1942
The various compounds used in dentifrice are sodium
fluoride, stannous fluoride, monofluorophosphate and
amine fluoride
A 200g tube of Colgate contains 1000ppm of fluoride
with the fluoride compound as Monofluorophosphate
43. A single brushing with a full ribbon of paste on
a brush head provides about one gram of
toothpaste and will expose the individual to
approximately 1mgF
For young children non fluoridated and non
abrasive toothpaste is recommended till the
child is 4 years of age
After 6 years of age fluoridated toothpaste
should be used
The amount should be pea sized and the paste
should be pressed into the bristles and not on
top of the brush
44. MOUTHRINSES
Fluoride mouthrinsing is one of the most widely used
caries preventive public health methods
Caries preventive agents used are Neutral sodium
fluoride, Acidulated phosphate fluoride and Stannous
fluoride
45. Sodium fluoride mouthrinses
Formulated at concentrations of
0.2%(900 ppm F) for weekly use
0.05%(225 ppm F) for daily use
These are used by forcefully swishing 10ml of the liquid
around the mouth for 60 sec before expectorating it
Recommendations for fluoride mouthrinses
Rinse and expectorate technique used for patients in
fluoride deficient communities
In patients with increased caries risk e.g. those undergoing
orthodontic treatment or radiotherapy
46. FLUORIDE GELS
Fluoride gel products include neutral
sodium fluoride and acidulated
phosphate fluoride with a fluoride
concentration of 5000 ppm and
stannous fluoride with a
concentration of 1000 ppm
The gels are either applied in trays or
brushed on teeth
Professionally applied – given twice
a year
Self applied – once a day or more
Home fluoride gels are not
recommended for children below 6
yrs and younger
47. Limitations of fluoride gels
They violate the principle of delivering low
concentration of fluoride at regular intervals
Toxicity hazard
Tedious to use on daily basis
48. Conclusion
Fluoridation is universally accepted by the dentists
and other medical professionals as being useful in
preventing tooth decay
They can be used in areas where there are no
central water supplies, where the fluoride conc. of
well water is low
Topically applied fluoride has more effect
compared to systemic fluorides
Topical fluorides are more economical.
But cannot be done on a large basis