The thoracic duct is the main lymphatic vessel that transports lymph from throughout the body. It begins at the cisterna chyli where it collects lymph from the lower body and abdomen. It ascends through the thorax, traveling along the vertebral column and passing through the diaphragm. In the neck, it arches forward and drains into the left subclavian vein. The thoracic duct transports around 4 liters of lymph per day to return excess tissue fluid to the bloodstream.