review the evidence (RCT & meta-analyses) concerning the best practices in contemporary Recurrent Pregnancy Loss and Thrombophilia depending on Eshre guideline 2017 and other EBM sources.
review the evidence (RCT & meta-analyses) concerning the best practices in contemporary Recurrent Pregnancy Loss and Thrombophilia depending on Eshre guideline 2017 and other EBM sources.
This talk was delivered for postgraduates and faculty of Dr. TMA Pai Hospital, Udupi on 07 March, 2017. This talk covered pathophysiology, screening, diagnosis, complications and management of diabetes mellitus in pregnancy.
This talk was delivered for postgraduates and faculty of Dr. TMA Pai Hospital, Udupi on 07 March, 2017. This talk covered pathophysiology, screening, diagnosis, complications and management of diabetes mellitus in pregnancy.
Chest injuries ranks 3rd after head injuries and extremity injuries in a case of multisystem trauma.It is of two types blunt chest trauma and peneterating chest trauma.The main cause of blunt chest trauma is road side accidents due to vehicles. Peneterating chest trauma is more dangerous and is common in war injuries and civilian terroism.In this ppp I have discussed some useful uncommon and important aspects of chest injuries
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
Introduction to AI for Nonprofits with Tapp NetworkTechSoup
Dive into the world of AI! Experts Jon Hill and Tareq Monaur will guide you through AI's role in enhancing nonprofit websites and basic marketing strategies, making it easy to understand and apply.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
3. Introduction
• Trauma is one of the leading causes of mortality,
morbidity and disability worldwide.
• trauma mostly affects people in their productive years of
life
• Deaths due to trauma tend to occur In three patterns
• - Immediate death (50%)
- Early deaths (30%)
- Late deaths (20%)
4. Definition and types
✔Trauma is tissue damage, which occurs due to transfer of
different forms of energy either
intentionally or unintentionally.
✔Trauma can be classified according to the Mechanism
- Blunt Injury: Caused by acceleration,
Deceleration,rotational or shearing force
- Penetrating Injury: Caused by a direct breach by
penetrating object.e.g Bullet injury, stab injury
5. Early management of trauma
• Management is depend on ATLS protocol
• It generally consists of a primary survey and
resuscitation followed by a secondary survey and
definitive Managements.
I- The primary survey and resuscitation.
• During this time, life-threatening injuries are
identified and simultaneously resuscitation is
begun
6. A- Airway maintenance
- It is assess of airway patency by inspect foreign body
and communication ability
- If the airway is compromised, use suctioning, jaw
trust positioning, oropharyngeal tube or endotracheal
tube to open it and taking care of cervical spine
B- Breathing and ventilation
- it is assessing of breathing adequacy
- examined by inspection, palpation, percussion and
auscultation
-The aim is to identify and manage life-threatening thoracic
conditions
7. Man.....
Interventions:Needle decompression
Chest tubes
Occlusive dressing
C- Circulation with bleeding control
-assessment of hemodynamic status by measuring blood pressure and
pulse rate, and inspecting skin color
Intervention
-Establish IV
-stop external hemorrhage by pressure, bandaging or
tourniquet
- take blood sample for cross match and start resuscitation with
Normal saline or Ringer’s lactate.
- if suspect cardiac tamponade -Cardiac tamponade decompression
Is done
8. Man.....
D- Disability/Neurologic assessment
-neurologic examination is done to assess consciousness.
The Glasgow Coma Scale is a quick method to determine
the level of consciousness
E-Exposure
patient should be completely undressed
Used for examination not to miss serious injuries
9. Man......
II- Secondary survey and definitive
Management
It include: - history
- examination of all body system
- investigations
- specific treatment
10. THORACIC INJURY
• 25% of all trauma deaths are a result of chest
injuries alone.
• Secondar cause of trauma death after head injury
• It involve: The chest wall ,Lung ,Mediastinal
structures, Diaphragm
11. Classification
Based on Mechanism
Blunt: 85%of all chest injury
result from MVA(75%),fall and crush of injury
Penetrating: 15%
Stab and gunshot wounds are common cause
It results in hemothorax and pneumothora.
12. Class....
Based on severity
Immediately life threatening
-Airway obstruction
-Tension pneumothorax
- Pericardial tamponade
-Open pneumothorax
-Massive haemothorax
-Flail chest
13. Class...
• Potentially life threateningcontusion
-Aortic injuries
-Tracheobronchial injuries
-Myocardial contusion
-Rupture of diaphragm
-Oesophageal injuries
-Pulmonary contusion
16. Tension Pneumothorax
Pathophysiology of Pneumothorax
• Normally, the pressure within the pleural space is
• negative in comparison to alveolar and atmospheric
pressure.
• If there is an opening made into the pleural space, air
rapidly rushes in due to the negative pressure.
• As pressure rises, lung tissue collapses.
• The amount of collapse is dependent on the
• size of the pneumothorax. E.g. if < 25%
• asymptomatic
17.
18. Ten......
• It is a life-threatening condition caused by the
continuous entrance and entrapment of air into the
pleural space
• Air flows in one way only which means only entering
• It compressing the lungs, heart, blood vessels, and other
structures in the chest.
21. Diagnosis
• Based on clinical
• CXR shouldn't be needed to identify because of it
delay therapeutic intervention and cause lethal
delay
Treatment
• Rapid insertion of Large bore needle in to the
2ndICS atMCL/mid clvicular line
• Follwed by Chest tube insertion
22. Open pneumothorax
• Occurs due to a large defect in thorax (>3cm)
• It leading to immediate equilibration between
intrathoracic and atmospheric pressure
• When wound is >2/3 of tracheal diameter
- inspiration pulls airs through wound into
pleural space
- air doesn't flow through the trachea in to the
lungs
23.
24. Clinical presentation
• Respiratory Distress
• Tachypnea and Dyspnea
• Asymmetrical chest expansion
• Hyper-resonant to percussion
• Diminished or absent breath sounds on affected
side
• Air movement through the wound; noticed as
• “bubbling” of blood at the wound site
26. Management
• Closing defect with sterile occlusive plastic dressing
taped on 3 sides to form a 1
• way valve
• chest tube inserted in a site remote
• from injury site.
• Definitive Rx may warrant debridement and closure
in the OR and Early referral
27. Haemothorax
• Hemothorax is a collection of bloody fluid in the pleural
space
• Following blunt or penetrating wound to the chest
• Sources:-Chestwallvessels,
• -Lungparenchyma
• -MajorThoracicvessels
• ClinicalPresentation-respiratory distress and shock.
• Dull percussion
• Absent breath sounds
• Tachycardia
• Hypotension due to blood loss.
29. Management
• correct the shock
• Insert IC drain
• Intubation (in some cases)
• Thoracotomy
• Indications
• - Drainage of 1500ml of blood or ongoing hemorrhage
of >200ml/hr over 3-4hrs
30. Cardiac Tamponade
• Is compression of the heart by
• an accumulation of fluid in the pericardial sac.
• It decrease cardiac output
• Most commonly the result of penetrating trauma
Clinical Presentation:
• it has Similar clinical presentation as tension pneumothorax
• Their difference is presence of hyperresonance on percussion
indicates tension pneumothorax, whereas the presence of
bilateral breath sounds indicates cardiac tamponade.
31. Investigation
CXR --enlarged heart shadow
Echocardiograpy --fluid in pericardial sac
Management
Needle pericardiocentesis
-for stabilization until definitive management,but there
may be high risk of iatrogenic injury to the heart
Definitive management
-Operative (sternetomy or left thoracotomy & repair of
the heart)
32. Flail chest
• 3 or more ribs fractured in 2 or more places.
Diagnosis:
-Paradoxical chest wall movement
-Poor air movement
-Hypoxia
Therapy:
Pain control
Pulmonary & physical therapy
Intubation and ventilator support if needed
Fluid restriction if possible
34. Classification of injury
• Bluntinjury(BAT)
- mostcommon.
- RTA(75%),Industrial,sporting
• Penetrating injury (PAT)
• •Lowenergy–Stab Wound
• •Highenergy-GSW mortality is high
35. Class..
• Based on hemodynamic stability
- hemodynamically ‘normal
- hemodynamically ‘stable
- hemodynamically ‘unstable’-immediate
Surgery is required
• A trauma laparotomy is the final step in the
pathway to delineate intra-abdominal injury
36. Management
• ATLS principles
• Base line labs
Hematocrit
Leukocyte count
Pancreatic enzyme ( serum amylase and lipase )
Liver function test
Urinanalysis
38. Focused Assessment with
sonography of trauma (FAST)
• To diagnosis free intraperitonial fluid
• Area of assessment
Pericardium
Perihepatic and hepatorenal
Presplenic
Pelvis
39. Limitations of FAST
• Injury to solid parenchyma, the retroperitoneum,
• or the diaphragm is not well seen
•Uncooperative patients, obesity, bowel gas, and
subcutaneous air interfere with image quality
•Less sensitive than peritoneal lavage for
hemoperitoneum (< 500ml)
•Blood cannot be distinguished from ascites or urine
•Subcapsular injuries cannot be detected
40. CT imaging
• Accurate for viisceral lesion and intraperitonal
hemorrhage
• Disadvantages
Insensitive for injury of the pancreas,diaphragm,small
bowel and mesentry
Diagnostic Peritoneal Lavage
Determine presences blood in peritoneum
44. Splenic Injuries
• Most commonly injured organ
• •~25% of blunt abdominal trauma
• •~7%penetrating abdominal trauma
Signs & Symptoms
• Feature of shock (pallor, tachycardia, restlessness,
tachypnea, anxiety, hypotension and decreased pulse
pressure
• Tenderness and abdominal rigidity in LUQ
• Abdominal distension
• Kehr's sign (pain after lying down and foot elevation
• Ballance's sign (fixed dullness to percussion on left and
shifting dullness on the right
46. Treatment
• Non operative management
Indication ~ hemodynamically stable
~ Lack of guarding and rigidity
~ Minimal evidence of blood loss
~ Children
• Operative management
-Splenorraphy
-Splenectomy
47. Hepatic Injuries
• Second most commonly injured intra-abdominal organ
• Associated with Rt 8-12 rib fractures
• Blunt trauma (15-20%)
• Penetrating trauma~37%
Signs & Symptoms
• RUQ penetrating or blunt trauma(hx)
• RUQ pain, Rt chest wall & shoulder pain
• Rigidity or guarding
• Reboundtenderness
• Signs of hemorrhage or shock
48. Mgt of Hepatic Injuries
• The management of liver injuries can be
• summarized as ‘thefourPs’:
• 1.Push;
• 2.Pringle (performed with avascular clamp occludes
the hepatic pedicle containing the portal vein,
hepatic artery, and common bileduct)
3.Plug;
4.Pack.
49. Abdominal Hollow Organ Injuries
• Small bowel is the most frequently injured
Blunt trauma
-Seat belt injuries and crush are most common
cause
- it has high risk of infection
Penetrating trauma:
–GSW, stab wound
50. Gastric & BowelTreatment
• Follow ATLS principles
• Surgical repair
• Diversion of the injured bowel with re anastomosis at a
later time