Erysipelas is an infectious disease mostly of growing or adult swine.
The disease may be acute, subacute, or chronic.
Although acute septicemic swine erysipelas can result in a high mortality rate, the greatest economic loss probably occurs from the chronic, nonfatal forms of the disease.
It may be clinically inapparent, may cause
acute illness
involving many animals, Sudden and unexpected deaths
chronic disease characterized by
enlarged joints, lameness, and endocarditis.
Rhomboid skin (diamond-skin) lesions are an inconsistent feature only associated with acute cases
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Fowl typhoid is a septicemic acute or chronic disease of domesticated birds.
The disease is worldwide distributed and natural outbreaks occur in chickens, turkeys, guinea fowl, peafowl, duckling and game birds such as quail, grouse and pheasant.
This can cause mortality in birds of any age.
Broiler parents and brown-shell egg layers are especially susceptible.
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Fowl typhoid is a septicemic acute or chronic disease of domesticated birds.
The disease is worldwide distributed and natural outbreaks occur in chickens, turkeys, guinea fowl, peafowl, duckling and game birds such as quail, grouse and pheasant.
This can cause mortality in birds of any age.
Broiler parents and brown-shell egg layers are especially susceptible.
local names, definition, etiology,epidemiology lifecycle, pathogenesis, clinical findings, necropsy finding, diagnosis,treatment, control and prevention
etiology, local names, definition, transmission, source of infection, epidemiology, pathogenesis, clinical signs, diagnosis, differential diagnosis, treatment prevention and control
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
The Indian economy is classified into different sectors to simplify the analysis and understanding of economic activities. For Class 10, it's essential to grasp the sectors of the Indian economy, understand their characteristics, and recognize their importance. This guide will provide detailed notes on the Sectors of the Indian Economy Class 10, using specific long-tail keywords to enhance comprehension.
For more information, visit-www.vavaclasses.com
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
2. Definition
Erysipelas is an infectious disease mostly of growing or adult
swine.
The disease may be acute, subacute, or chronic.
Although acute septicemic swine erysipelas can result in a high
mortality rate, the greatest economic loss probably occurs from
the chronic, nonfatal forms of the disease.
It may be clinically inapparent, may cause
acute illness
involving many animals, Sudden and unexpected deaths
chronic disease characterized by
enlarged joints, lameness, and endocarditis.
Rhomboid skin (diamond-skin) lesions are an inconsistent
feature only associated with acute cases
large animal medicine 2
3. Etiology
The causative agent is a bacterium, Erysipelothrix rhusiopathiae.
Gram-positive, facultatively anaerobic , small rods (smooth form) or filaments
(rough form)
can grow on non-enriched media produces pinpoint and non hemolytic
colonies after incubation for 24 hr and produce Small colonies, with
incomplete haemolysis in 48 hours
Can grow in temperature range of 5 – 420; and PH range of 6.7 – 9.2.
Colonies on agar media are grayish translucent
The organism is nonmotile, non-spore-forming, and non-acid-fast
A number of different serotypes (32 )have been identified, usually types 1 and
2 in pigs.
Many of the serotypes have been regrouped and called Erysipelothrix
tonsillarum.
This is a nonpathogenic type found in the tonsil that is morphologically and
biochemically similar to E. rhusiopathiae but has a very distinctive genetic
profile.
In humans E. rhusiopathiae causes erysipeloid, a local skin lesion that occurs
chiefly as an occupational disease of persons engaged in handling and
processing meat and mostly veterinarian
large animal medicine 3
4. Epidemiology
The disease is worldwide in distribution and in most countries
has reached a level of incidence sufficient to cause serious
economic loss due to deaths of pigs and devaluation of pig
carcasses because of arthritis.
Indoor confinement of swine decreased pigs contact with
contaminated soil, therefore the occurrence of the disease has
decreased markedly
The exception to this would be outdoor units where no vaccination
is practiced.
Historically disease occurred most commonly in unvaccinated
growing pigs over 3 months of age and adults.
Disease due to E. rhusiopathiae is uncommon in pigs under 8
weeks of age why ?
because of maternal antibody protection provided by the sow
via colostrum.
large animal medicine 4
5. Epidemiology con…..
The infection, usually with serotypes 1a or 2, has also been demonstrated in
wild boars, so these should not be forgotten as a reservoir
Morbidity and case fatality rates in pigs vary considerably from area to area.
Because of variations in virulence of the particular strain of the organism involved in
infection.
Sources of Infection
Domestic pigs
Carrier animals’ excreta-faeces, urine
Contaminated water and feed
Body secretions-saliva, nasal
Mode of Transmission
Ingestion
Natural infection through skin wound
Biting flies
Intra-uterine infection
Soil contaminated with organisms
Contaminated water also aids the spread of infection
large animal medicine 5
6. Epidemiology con…..
Predisposing factors
Age
Genetics
Immunity
Non- infectious disease
Stress due to environment or management (nutrition, ambient
temperature, and fatigue)
Worm infestation
Concurrent infection
Alkaline soil
large animal medicine 6
7. Epidemiology con…..
Swine less than 3 months or more than 3 years of age are generally least
predisposed to SE.
The relationship of age to susceptibility may be explained by naturally
acquired passive immunity in the young and active immunity following
subclinical infection in older animals.
Suckling pigs of immune sows are immune to infection for several weeks
after birth.
The degree and duration of passive immunity are related to the immune
status of the sow.
Parasitic infestations have been reported to increase the severity of clinical
SE.
Susceptibility of swine to acute SE can be enhanced by subclinical toxicity
from aflatoxin in the feed.
Sudden outbreaks of acute SE may be the result of a combination of
susceptibility of the animals and virulence of the causative organism
large animal medicine 7
8. Pathogenesis
Ingestion of contaminated feed and water usually allows E.
rhusiopathiae to gain access to the body, probably through the tonsils or
other lymphoid tissue of the digestive tract (the organism often can be
cultured from tonsils of normal swine).
Less often, contaminated skin wounds may permit entry.
In acute erysipelas, and perhaps in other forms of the disease, a
bacteremia develops and leads to spread of organisms throughout the
body.
The precise mechanism by which E. rhusiopathiae causes disease is
speculative.
The organism produces neuraminidase(is a factor in pathogenicity SE )
an enzyme that cleaves mucopolysaccharides in cell walls which may
mediate the widespread vascular damage that accompanies SE.
Vascular damage leads to thrombosis and interference with
microcirculation in capillaries and venules at many sites.
large animal medicine 8
9. Pathogenesis cont….
In chronic arthritic cases, there
is a vasculitis with exudation of
fibrin into perivascular tissues
and joint(s).
There also is marked villous
proliferation of the synovial
membrane. Joint lesions are
more proliferative than
exudative.
Connective tissue formation
around joints is stimulated,
apparently by perivascular
fibrin, and the joint capsule
may be thickened.
Persistence of inflammation
around an affected joint may be
from a few living bacteria in the
joint or it may be the result of
hypersensitivity to remaining
bacterial antigens.
large animal medicine
Organ : Joint.
Disease : Swine Erysipelas.
Macro : Arthritis with ankylosis.
9
10. Pathogenesis……..
Vegetative, valvular endocarditis, another manifestation of chronic
erysipelas, is less common than joint involvement.
Emboli of E. rhusiopathiae are believed to cause inflammation of blood
vessels within heart valves.
In the inflammatory process, the endocardium is breached and
bacterial colonies are established at the site.
Fibrin is deposited there and slowly organized to form nodular
vegetations.
Emboli that arise from vegetations can cause sudden death.
Interestingly, outbreaks of vegetative endocarditis can occur in the
absence of other clinical signs.
In older, susceptible swine, various stresses (heat, aflatoxin, poor
nutrition) have been suspected of playing a role in precipitating
outbreaks.
large animal medicine 10
11. large animal medicine
Organ : Endocardium (heart).
Disease : Swine Erysipelas.
Macro : Vegetative endocarditis.
11
12. Clinical signs
Clinical signs of swine erysipelas can be divided into acute, subacute, and chronic
forms.
Subclinical infection can also occur where no disease is apparent, but may lead to
chronic disease.
The septicacmic and cutaneous ('diamond ') forms are acute while arthritis and
vegetative endocarditis are chronic forms of the disease.
Septicaemia occurs after an incubation period of 2 to 3 days.
During an outbreak of acute disease, some pigs may be found dead and others are
febrile, depressed and walk with a stiff, stilted gait or remain recumbent. Mortality
may be high in some outbreaks. Pregnant sows with the septicaemic form may
abort.
In the diamond-skin form, systemic signs are less severe and mortality rates are
much lower than in animals with septicaemia.
large animal medicine 12
13. Clinical sign cont….
Acute
After an incubation period of 1-7 days
Sudden death
High rise in temp.(104-106°F),
Stilly gait and get up with difficult
Suspended bowl material movement
Pigs remain depressed and burrow in the bedding
Conjunctivitis and vomition
Anorexia and thirst are common.
Slightly pink to dark purple area which raised and firm to touch
Diamond skin lesions
Sick pigs often have reddened or cyanotic skin, especially about the ears, snout,
jowls, throat and ventral abdomen.
large animal medicine 13
14. Acute swine
erysipelas, skin form
Acute swine erysipelas
typical raised pink lesions
with diamond shaped
dark red/black central
areas.
Diamond skin lesions in pig
large animal medicine
14
16. Clinical signs
.
subacute
characteristic skin lesions, inappetance, and a mild fever.
the skin lesions may not persist for more than a few days.
symptoms are similar to acute erysipelas although they will be milder.
chronic form
This is the most common form of erysipelas
may follow acute or subacute disease as well as subclinical infection and is
characterised most commonly by arthritis.
arthritis mainly involved joints are hock, stifles, knee, and elbow and Losses occur
due to lameness, ill-thrift and carcass condemnation.
Joints are stiff, enlarged, hot and painful
Sloughing of the tip of the tail or tips of the ears can occur but can have other
large animal medicine
causes.
Signs of heart problems due to infection of the heart valves may be evident
occasionally and will be most obvious after exertion, which may lead to sudden
death.
Paraplegia may occur when intervertebral joints are involved or when there is gross
distortion of limb joints.
16
17. Necropsy finding
In acute infection, in addition to skin lesions
lymph nodes are usually enlarged and congested
the spleen is swollen, and the lungs are edematous and congested.
Petechial hemorrhages may be present on the kidneys, epicardium
and endocardium
In chronic erysipelas
valvular endocarditis is seen as proliferative, granular growths on the
heart valves, and embolisms and infarctions may develop.
Mitral valve is more frequently affected
Infarction of kidney and liver
Arthritis may involve joints of one or more legs or the intervertebral
articulations; the joint enlargement is proliferative but nonsuppurative,
and tags of granulation tissue form in the articular cavity.
there may be proliferation and erosion of the articular cartilage; this may be
followed by fibrosis and ankylosis of the joint.
large animal medicine 17
20. diagnosis
Diagnosis can be based on
Epidemiology
Clinical sign
Necropsy findings
Serology (not a reliable method of diagnosis, it only indicates exposure to the
organism)
Clinical and bacteriologic examinations are the most reliable means of
diagnosis of acute SE.
• Clinical diagnosis is based on signs, typical lesions in several pigs and favorable
response of acute cases to high doses of penicillin and/or hyperimmune serum.
• Pigs in the early stage of acute erysipelas often respond favorably; severe or
chronic cases do not.
• In acute cases, signs of special value in diagnosis include exceptionally high
temperatures, evidence of marked pain in multiple joints and typical skin lesions.
NB. Diamond-skin’ lesions are pathognomonic for swine erysipelas.
If the diamond markings are not obvious to the eye they can be felt if the hand is
run over the skin of the back or behind the back legs and over the flanks. This
will assist in diagnosis
large animal medicine 20
21. Samples for confirmation of diagnosis
Bacteriology
culture swabs from joints
synovial membranes in culture media,
heart valve masses, spleen, kidney, and bone
marrow, particularly from a long bone.
Smears of heart blood are particularly useful in the
first 1-2 days of the acute diseases.
Bacteriological examination of subacute cases is less
successful and chronic cases not successful.
Histology - formalin-fixed synovial membranes, heart
valve masses, spleen, kidney, skin lesions
large animal medicine 21
22. Diagnosis cont…..
Bacteriologic Diagnosis
• Isolation from the acutely affected animal provides a definite laboratory
diagnosis of SE.
• Hemoculture is a useful diagnostic aid in living animals, but specimens
should be taken from several affected animals in the herd, as the presence of
the organism in the blood of an individual may be inconstant.
• At necropsy of a pig that has died in the acute phase, the organism is easily
cultured from a variety of body organs (heart, lungs, liver, spleen, kidneys,
joints).
• If the illness has persisted for several days, however, the organism often can
no longer be cultured from internal organs but may still be found in the
joints.
• Under these conditions it is important to take several specimens of fluid
and synovial tissue from as many synovial sacs of a joint as possible,
because the organisms may be present in small numbers and limited to
certain areas.
• A firm diagnosis is more difficult with chronic cases.
• Culture attempts on multiple joints often fail. However, the appearance of
many cases of arthritis in growing pigs is more typical of erysipelas than of
other diseases.
• NB. Care should be taken to avoid accidental skin infection, as the
organism is pathogenic for humans
large animal medicine 22
23. Differential diagnose
Erysipelas must be differentiated from
septicemias of pigs
Acute disease may be confused with the other septicemias affecting pigs, but pigs
with erysipelas usually show the characteristic skin lesions and are less depressed
than pigs with hog cholera or salmonellosis.
Septicemic salmonellosis characterized by Gross blue-purplish
discoloration of the skin especially the ears, Some evidence of enteritis and
polypnea and dyspnea
Hog cholera characterized by large numbers of pigs affected quickly,
weakness, fever, muscle tremors, skin discoloration and rapid death;
convulsions are also common
Streptococcal septicemia and arthritis They are almost entirely
confined to suckling pigs in the first few weeks of life and Streptococcal
septicemia is usually associated with Actinobacillus suis.
Streptococcal endocarditis has a similar age distribution as erysipelas
endocarditis and bacteriological examination is necessary to differentiate
them.
large animal medicine 23
24. Differential diagnose con…
arthritides of pigs
The chronic disease characterized by joint disease occurs in pigs
of all ages but less commonly in adults and must be differentiated
from the following conditions:
Glasser's disease accompanied by a severe painful dyspnea.
At necropsy there is serositis and meningitis
Mycoplasma arthritis Generally it affects pigs less than 10
weeks of age and produces a polyserositis as well as polyarthritis
however; Mycoplasma hyosynoviae can produce simple
polyarthritis in growing pigs
Rickets and chronic zinc poisoning produce lameness in
pigs but they occur under special circumstances, are not
associated with fever, and rickets is accompanied by
abnormalities of posture and gait that are not seen in erysipelas
Foot rot of pigs is easily differentiated by the swelling of the
hoof and the development of discharging sinuses at the coronet
large animal medicine 24
25. Treatment
Antimicrobial therapy
Penicillin and anti-erysipelas serum comprise the standard treatment. often
administered together by dissolving the penicillin in the serum
The treatment of choice for acute erysipelas is administration of penicillin.
E. rhusiopathiae is highly sensitive to this antibiotic, and treatment early in an
acute outbreak usually results in dramatic response within 24-36 hours.
Specific treatment regimens generally involve giving penicillin alone or in
combination with other antibiotics or antiserum (occasionally both) to provide
a longer action.
Eg. , long-acting penicillin consisting of a combination of 150,000 units
procaine penicillin G and 150,000 units benzathine penicillin G/cm3, may be
given I/M at a single dose of 5000-10,000 units/pound (454 g) to visibly sick
pigs
The entire herd may be treated with tetracycline in the drinking water: 500
mg/gallon, 132 mg/L) until 5 days after no sick pigs are observed
The entire herd may also be given antiserum if the outbreak is very severe.
As an alternative, long-acting penicillin may be given in severe outbreaks, and
procaine penicillin G in less severe cases.
large animal medicine 25
26. Treatment cont….
The use of antiserum for treatment of suckling pigs is a fairly common
practice.
Initiation of a vaccination program in previously unvaccinated herds
where outbreaks occur is strongly recommended.
For maximum effectiveness the serum must be given early in the course
of the disease. The recommended therapeutic dose, given S/C, varies
from to
5 to 10 mL for pigs weighing less than 50 pounds (23 kg)
20-40 mL for pigs weighing more than 100 pounds (45 kg).
Penicillin alone is usually adequate when the strain has only mild
virulence at Standard dose of 50 000 IU/kg BW of procaine penicillin I/M
for 3 days
chronic cases do not respond well to treatment because of structural
damage that occurs in joints and inaccessibility of the organism in the
endocardial lesions.
So there is no practical treatment for chronic SE.
Experimentally, the administration of antiinflammatory agents has
provided some alleviation of the effects of chronic arthritis, and they may
be used in treatment of especially valuable individual animals.
large animal medicine 26
27. Control
Routine vaccination is the best available means of controlling erysipelas
Successful control depends on good hygiene, biosecurity, reduction of stress,
an effective 6-monthly vaccination policy, preferably two doses, for all
animals including boars over 3 months of age, as well as rapid diagnosis,
quarantine, and treatment.
Acute outbreaks of SE usually can be controlled by administering penicillin
and/or erysipelas antiserum to affected pigs along with antimicrobials
added to the drinking water until no sick pigs have been observed for at
least 3 days.
Eradication of erysipelas on individual piggeries is considered impractical
due to the large number of 'carrier' pigs and other 'carrier' species including
birds and rodents.
General hygienic precautions should be adopted.
Clinically affected animals should be disposed of quickly and all
introductions should be isolated and examined for signs of arthritis and
endocarditis
All animals dying of the disease should be properly incinerated to avoid
contamination of the environment
A combination of regular vaccination, good sanitation, the elimination of
carriers with skin and joint lesions, and appropriate quarantine measures
for purchased stock usually will aid control of SE.
large animal medicine 27
28. PREVENTION
Prevention of SE is best accomplished by sound practices of
herd health management, including a program of
immunization.
General Management Practices
Swine should be raised according to sound husbandry practice
relative to nutrition, housing, and condition of lots and
pastures, and they should be observed regularly for deviations
from their usual attitude
purchased animals should be isolated for at least 30 days.
It is advisable to eliminate chronically affected swine from the
herd, as they can remain carriers of the organism indefinitely.
Good sanitation is important in general herd management and
is essential following the cessation of an outbreak
Walls and floors should be cleaned and disinfected.
large animal medicine 28
29. PREVENTION
Immunization
The immunizing agents include
1. Hyperimmune serum (anti - erysipelas serum)
2. Vaccines
1. anti - erysipelas serum
Administration of 5 - 20 ml of serum parenteraly amount depending on age
will protect in contact pigs for a minimum of 1 - 2 weeks.
Suckling pigs in herds where the disease is endemic should receive 10 ml of
hyperimmune serum during the first week of life and at monthly intervals
until they are actively vaccinated
• which can be done as early as 6 weeks –if sows have not been vaccinated
In herds where sows are routinely vaccinated prior to farrowing -piglet
vaccination will be delayed until 10 - 12 weeks of age for effective active
immunity.
• Repeated administration of the serum may cause anaphylaxis because of its
equine origin
large animal medicine 29
30. PREVENTION
2. vaccination
• vaccination using killed bacterins or, attenuated vaccines prepared by serial
passage or strains of low virulence for pigs
• The formalin-killed, aluminum-hydroxide-adsorbed bacterin confers an
immunity that, in most instances, protects growing pigs from acute disease
until they reach market age. An oral vaccine of low virulence is also used.
Generally for prevention of SE
• All gilts and young boars should be vaccinated twice 2-4 weeks apart
(according to manufacturer’s instructions) before entering the breeding herd.
• Sows should be vaccinated 3-4 weeks prior to farrowing
• boars should be vaccinated every 6 months.
• Progeny may need vaccination if there is a high challenge.
• N.B Vaccination raises the level of immunity but does not provide complete
protection
• If disease outbreak occurs despite a vaccination program, review
hygiene and management practices and consider changing to all-in-all-out
production systems.
large animal medicine 30