UG CLASS

1. DR SARAVANAKUMAR

2.  EGYPTIANS
 GREEKS – HIPPOCRATES
 ROMANS – GALEN – LAUDABLE PUS
 19TH CENTURY – KOCHS , LOUIS PASTEUR
 The Austrian obstetrician Ignac Semmelweis-
HAND WASHING
 JOSEPH LISTER
 antibiotic penicillin- Alexander Fleming in 1928

3.  It must be found in every case
 It should be possible to isolate it from the host
and grow it in culture
 It should reproduce the disease when injected
into another healthy host
 It should be recovered from an experimentally
infected host

4.  Malnutrition
 Metabolic disease (diabetes, uraemia, jaundice)
 Immunosuppression (cancer, AIDS, steroids,
chemotherapy and radiotherapy)
 Colonisation and translocation in the
gastrointestinal tract
 Poor perfusion (systemic shock or local
ischaemia)
 Foreign body material
 Poor surgical technique (dead space,
haematoma)

7.  LOCAL AND SYSTEMIC PRESENTATION
 SYSTEMIC – SIRS , MODS
 SOURCE – PRIMARY OR ENDOGENOUS
SECONDARY OR HOSPITAL
ACQUIRED

14.  Gas gangrene
 Tetanus
 Necrotizing fasciitis

16.  Prevention
 Antibiotic prophylaxis and treatment
 Antibiotic policy and guide lines
 Effective wound management