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SPECIAL SENSES
Cornea
Retina
Optic nerve
Prof.J.Anbalagan
Special sensory organs
Olfactory mucosa
Gustatory cells
Retina
Internal ear
– cochlea
– Semicircular canal
Eyeball
Eye lid
Skin
– Stratified squamous
keratinized
– dermis
Connective tissue layer
Skeletal muscle
(orbicularis oculi)
Tarsal plate with glands
Conjunctiva
– Stratified squamous non
keratinized
Cornea
Five layered structure
– Outer corneal
epithelium
– Bowman’s membrane
– Substantia propria
– Descemet’s membrane
– Inner endothelium
Corneal epithelium
– Thin Stratified squamous non
keratinized-5 LAYER
– Papilla absent
– Straight plane avoids refraction
Bowman’s membrane
– Anterior limiting membrane
– Homogenous amorphous with
fine collagen
– Forms basement membrane for
corneal epithelium
Substantia propria
– Stroma of cornea
– Transparent
– Parallel arranged collagen
fibers
– Ground matrix
– glycoaminoglycans+fibroblast
– Collagen are arranged in
alternate lamellae with regular
spacing for light transmission
Descemet’s membrane
– Posterior limiting
membrane
– Thin and homogenous
– Layers continues into irido
corneal angle
Endothelium
– Single polygonal cells on
a basement membrane
RETINA
Nervous coat
Extends from optic disc
to ora serrata
Posterior part of retina
shows yellow spot
macula lutea
Optic disc – area where
optic nerve emerges
Layers of retina
1. PIGMENT LAYER
2. LAMINA OF RODS AND CONES
3. EXTERNAL LIMITING MEMBRANE
4. OUTER NUCLEAR LAYER
5. OUTER PLEXIFORM LAYER
6. INNER NUCLEAR LAYER
7. INNER PLEXIFORM LAYER
8. GANGLION CELL LAYER
9. LAMINA OF NERVE FIBERS
10. INTERNAL LIMITING MEMBRANE
PIGMENT EPITHELIUM
Low cubical cells
Basement membrane known
as Bruch’s membrane
Cells faces towards rods and
cones
Appear black due to melanin
pigments
One cell contacts > 12 rods
and cones
functions
– Phagocyte,
– antireflection of light,
– blood retinal barrier
Pigment cells
Rods and Cones
Photoreceptors
Cones are wider and tapers at
the end
Rods are narrow and cylindrical
Under EM they exhibit outer and
inner segments
Inner segments contains
mitochondria for energy
Outer segment shows discoidal
membrane
External limiting membrane
– Sieve like membrane
– Supports rods and cones
– Appears pink linear marking
– Represents zona adherens
of Muller cells
Outer nuclear layer
– Nucleus of rods and cones
– Several layers
ONL
OLM
Outer plexiform layer
– Synaptic area between rods
and cones with
– Bipolar neurons
– Horizontal cells
– Amacrine cells
Inner nuclear layer
– Shows nucleus of bipolar,
horizontal cells, amacrine
cells, Muller cells
Inner plexiform layer
– Synaptic process of
bipolar, amacrine, Muller
with ganglion cells
– Plexiform appearance
Ganglion layer
– Cell body and nucleus of
large ganglion cells and
amacrine cells
Nerve fibers
– axons of ganglion
cells
Internal limiting
membrane
– Homogenous layer
– Formed by end feet of
Muller cell and
astrocytes
RETINA- LAYERS
Microstructure of Retina
OPTIC NERVE
MENINGES
– DURA
– ARACHNOID
– PIA
NERVE FIBERS
– MYELINATED
– ARRANGED IN FASCICULI
– CENTRAL ARTERY OF RETINA
OPTIC NERVE
Cochlea
Special senses (2)
Special senses (2)
Special senses (2)
Special senses (2)

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Special senses (2)

  • 2. Special sensory organs Olfactory mucosa Gustatory cells Retina Internal ear – cochlea – Semicircular canal
  • 3.
  • 5. Eye lid Skin – Stratified squamous keratinized – dermis Connective tissue layer Skeletal muscle (orbicularis oculi) Tarsal plate with glands Conjunctiva – Stratified squamous non keratinized
  • 6. Cornea Five layered structure – Outer corneal epithelium – Bowman’s membrane – Substantia propria – Descemet’s membrane – Inner endothelium
  • 7. Corneal epithelium – Thin Stratified squamous non keratinized-5 LAYER – Papilla absent – Straight plane avoids refraction Bowman’s membrane – Anterior limiting membrane – Homogenous amorphous with fine collagen – Forms basement membrane for corneal epithelium
  • 8. Substantia propria – Stroma of cornea – Transparent – Parallel arranged collagen fibers – Ground matrix – glycoaminoglycans+fibroblast – Collagen are arranged in alternate lamellae with regular spacing for light transmission
  • 9. Descemet’s membrane – Posterior limiting membrane – Thin and homogenous – Layers continues into irido corneal angle Endothelium – Single polygonal cells on a basement membrane
  • 10. RETINA Nervous coat Extends from optic disc to ora serrata Posterior part of retina shows yellow spot macula lutea Optic disc – area where optic nerve emerges
  • 11. Layers of retina 1. PIGMENT LAYER 2. LAMINA OF RODS AND CONES 3. EXTERNAL LIMITING MEMBRANE 4. OUTER NUCLEAR LAYER 5. OUTER PLEXIFORM LAYER 6. INNER NUCLEAR LAYER 7. INNER PLEXIFORM LAYER 8. GANGLION CELL LAYER 9. LAMINA OF NERVE FIBERS 10. INTERNAL LIMITING MEMBRANE
  • 12. PIGMENT EPITHELIUM Low cubical cells Basement membrane known as Bruch’s membrane Cells faces towards rods and cones Appear black due to melanin pigments One cell contacts > 12 rods and cones functions – Phagocyte, – antireflection of light, – blood retinal barrier
  • 14. Rods and Cones Photoreceptors Cones are wider and tapers at the end Rods are narrow and cylindrical Under EM they exhibit outer and inner segments Inner segments contains mitochondria for energy Outer segment shows discoidal membrane
  • 15. External limiting membrane – Sieve like membrane – Supports rods and cones – Appears pink linear marking – Represents zona adherens of Muller cells Outer nuclear layer – Nucleus of rods and cones – Several layers ONL OLM
  • 16. Outer plexiform layer – Synaptic area between rods and cones with – Bipolar neurons – Horizontal cells – Amacrine cells Inner nuclear layer – Shows nucleus of bipolar, horizontal cells, amacrine cells, Muller cells
  • 17. Inner plexiform layer – Synaptic process of bipolar, amacrine, Muller with ganglion cells – Plexiform appearance Ganglion layer – Cell body and nucleus of large ganglion cells and amacrine cells
  • 18. Nerve fibers – axons of ganglion cells Internal limiting membrane – Homogenous layer – Formed by end feet of Muller cell and astrocytes
  • 20.
  • 21.
  • 23. OPTIC NERVE MENINGES – DURA – ARACHNOID – PIA NERVE FIBERS – MYELINATED – ARRANGED IN FASCICULI – CENTRAL ARTERY OF RETINA