Systemic lupus erythematosus (SLE) is an autoimmune disease that causes inflammation in various tissues of the body. It most commonly affects women of childbearing age. The immune system mistakenly attacks healthy cells and organs, causing symptoms like joint pain and skin rashes. While the exact cause is unknown, genetic and environmental factors are believed to play a role. There is no cure for SLE, but treatment aims to reduce inflammation and manage symptoms. Medications may include steroids, anti-malarials, chemotherapy, and immunosuppressants. With proper treatment, many people can lead normal lives despite having SLE.
SLE still an enigma where both patient and health care professionals are blind and do more harm than saving the patient. Hope in future anything can be done to save the patient from the grip of lupus,
Lupus is a chronic autoimmune disease that occurs when a person's immune system attacks their own tissues and organs. Learn about the symptoms of lupus, how it is diagnosed and new treatment options to live well with lupus.
Recent advances in diagnosis & management of SLEShadab Ahmad
Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage mediated by tissue binding autoantibodies and immune complexes.
90 % of patients at diagnosis are women of childbearing age groups.
Highest prevalence is in black women and lowest is in white men.
Lupus Secrets for Nonmedical people patients and families to learn how to liv...Donald Thomas
Dr. Donald Thomas at lupusencyclopedia@gmail.com , author of The Lupus Encyclopedia presents a talk for the Maryland Lupus Summit 2013 giving tips about how to fight against lupus. His book answers "What is lupus?" as well as goes into detail about the symptoms (such as rash and arthritis) of lupus and related conditions such as fibromyalgia and Sjogren's syndrome. Go to www.facebook.com/LupusEncyclopedia , click "LIKE" to get daily tips and facts about learning to live with and fight lupus
SLE still an enigma where both patient and health care professionals are blind and do more harm than saving the patient. Hope in future anything can be done to save the patient from the grip of lupus,
Lupus is a chronic autoimmune disease that occurs when a person's immune system attacks their own tissues and organs. Learn about the symptoms of lupus, how it is diagnosed and new treatment options to live well with lupus.
Recent advances in diagnosis & management of SLEShadab Ahmad
Systemic lupus erythematosus (SLE) is an autoimmune disease in which organs and cells undergo damage mediated by tissue binding autoantibodies and immune complexes.
90 % of patients at diagnosis are women of childbearing age groups.
Highest prevalence is in black women and lowest is in white men.
Lupus Secrets for Nonmedical people patients and families to learn how to liv...Donald Thomas
Dr. Donald Thomas at lupusencyclopedia@gmail.com , author of The Lupus Encyclopedia presents a talk for the Maryland Lupus Summit 2013 giving tips about how to fight against lupus. His book answers "What is lupus?" as well as goes into detail about the symptoms (such as rash and arthritis) of lupus and related conditions such as fibromyalgia and Sjogren's syndrome. Go to www.facebook.com/LupusEncyclopedia , click "LIKE" to get daily tips and facts about learning to live with and fight lupus
this research is made by a dental student (me) under supervision of our oral medicine specialist dr. muhassad almudhafer and this research is collected from several articles hope u like it
this my email if u would like to contact me - mnmmnz4503.mm@gmail.com
SLE is an autoimmune disease resulting in butterfly rash and various other symtoms,a brief introduction and diagnosis and causes are mentioned in this ppt.
Systemic means affects multiple organs.
Lupus is the Latin word for wolf meaning disease affecting skin where the skin lesions look like wolf bite.
Erythematosus means reddening of the skin.
Systemic Lupus Erythematosus or SLE, sometimes also called just lupus is a disease that’s systemic and affects a wide variety of organs, but notably often causes red lesions on the skin.
Systemic Lupus Erythematosus(SLE) is a chronic, nonspecific autoimmune inflammatory disease that typically affects multiple organs and systems, including the skin, joints, muscles, lungs, heart, kidneys, and the CNS and circulatory system.
Individuals with SLE are noted with the production of antibodies and inflammatory responses that are mistakenly directed at their own tissue.
We understand the unique challenges pickleball players face and are committed to helping you stay healthy and active. In this presentation, we’ll explore the three most common pickleball injuries and provide strategies for prevention and treatment.
QA Paediatric dentistry department, Hospital Melaka 2020Azreen Aj
QA study - To improve the 6th monthly recall rate post-comprehensive dental treatment under general anaesthesia in paediatric dentistry department, Hospital Melaka
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
CHAPTER 1 SEMESTER V PREVENTIVE-PEDIATRICS.pdfSachin Sharma
This content provides an overview of preventive pediatrics. It defines preventive pediatrics as preventing disease and promoting children's physical, mental, and social well-being to achieve positive health. It discusses antenatal, postnatal, and social preventive pediatrics. It also covers various child health programs like immunization, breastfeeding, ICDS, and the roles of organizations like WHO, UNICEF, and nurses in preventive pediatrics.
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Guillermo Rivera
This conference will delve into the intricate intersections between mental health, legal frameworks, and the prison system in Bolivia. It aims to provide a comprehensive overview of the current challenges faced by mental health professionals working within the legislative and correctional landscapes. Topics of discussion will include the prevalence and impact of mental health issues among the incarcerated population, the effectiveness of existing mental health policies and legislation, and potential reforms to enhance the mental health support system within prisons.
Leading the Way in Nephrology: Dr. David Greene's Work with Stem Cells for Ki...Dr. David Greene Arizona
As we watch Dr. Greene's continued efforts and research in Arizona, it's clear that stem cell therapy holds a promising key to unlocking new doors in the treatment of kidney disease. With each study and trial, we step closer to a world where kidney disease is no longer a life sentence but a treatable condition, thanks to pioneers like Dr. David Greene.
Medical Technology Tackles New Health Care Demand - Research Report - March 2...pchutichetpong
M Capital Group (“MCG”) predicts that with, against, despite, and even without the global pandemic, the medical technology (MedTech) industry shows signs of continuous healthy growth, driven by smaller, faster, and cheaper devices, growing demand for home-based applications, technological innovation, strategic acquisitions, investments, and SPAC listings. MCG predicts that this should reflects itself in annual growth of over 6%, well beyond 2028.
According to Chris Mouchabhani, Managing Partner at M Capital Group, “Despite all economic scenarios that one may consider, beyond overall economic shocks, medical technology should remain one of the most promising and robust sectors over the short to medium term and well beyond 2028.”
There is a movement towards home-based care for the elderly, next generation scanning and MRI devices, wearable technology, artificial intelligence incorporation, and online connectivity. Experts also see a focus on predictive, preventive, personalized, participatory, and precision medicine, with rising levels of integration of home care and technological innovation.
The average cost of treatment has been rising across the board, creating additional financial burdens to governments, healthcare providers and insurance companies. According to MCG, cost-per-inpatient-stay in the United States alone rose on average annually by over 13% between 2014 to 2021, leading MedTech to focus research efforts on optimized medical equipment at lower price points, whilst emphasizing portability and ease of use. Namely, 46% of the 1,008 medical technology companies in the 2021 MedTech Innovator (“MTI”) database are focusing on prevention, wellness, detection, or diagnosis, signaling a clear push for preventive care to also tackle costs.
In addition, there has also been a lasting impact on consumer and medical demand for home care, supported by the pandemic. Lockdowns, closure of care facilities, and healthcare systems subjected to capacity pressure, accelerated demand away from traditional inpatient care. Now, outpatient care solutions are driving industry production, with nearly 70% of recent diagnostics start-up companies producing products in areas such as ambulatory clinics, at-home care, and self-administered diagnostics.
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
3. DEfinition :
SLE or Systemic lupus erythema is an autoimmune disease characterized by acute and
chronic inflammation in various tissues of the body, in most cases, the disease affects
for many parts of the body and called then Lupus Erythema systemic and include
devices that may be infected with the disease of the skin, joints, kidneys, nervous
system, lungs, heart , blood cells and platelets.
4. iS it a common DiSEaSE?
4-Percentage of infected females to males is 9 to 1 while increasing the
proportion of infected males in the younger children - less than 15 years
1-Lupus disease,is a rare disease that affects about 5 children per million annually.
2 - infection before the age of five is not common before
puberty.
3-Women of childbearing age (15-45 years) are most affected by this
disease in this age period.
5. cauSE of thE DiSEaSE
• In fact, the cause of this disease is not known,
the immune system lose the ability to differentiate between cells and tissues of
the body and objects alien him, which leads to the production of antibodies to
self-identify the cells of the body. Like alien cell and tries to eliminate them and
get rid of them is produced by the inflammation that infect different organs like
joints, kidney, skin and other .
• inflammation of the affected means that the organ becomes red, swollen, high
temperature and sometimes painful.
• When inflammation continues for as long as is the case of this disease, the
damage of tissues and organs may occur with an imbalance in the natural
functions .
For this reason, the purpose of treatment of this disease is to minimize
the inflammation.
they thought the caused of the imbalance in the immune system due to random
environmental factors in addition to several genetic factors.
6. SyStemic lupuS erythematoSuS and geneticS
This disease is not genetically because it is not transmitted from parents to
their children, however children may inherit some genes from their parents
makes them more susceptible to this disease, but this does not necessarily
mean these children will be affected by this disease but may increase
vulnerability to infection.
7. iS it contagiouS?
No, it can not be transmitted from one person to another .
What are the main SymptomS?
1- swelling in the joints .
2- skin rash and redness on the face and ears.
3- hair loss and sores in the mouth.
4-perhaps the infection of disease on organs of the body such as the
respiratory tract, causing pain and shortness of breath .
5-The disease affects the kidneys and lead to the secretion of protein or albumin in
the urine.
6-rise in blood pressure and deterioration in kidney function.
8.
9. A- decrease in the number of blood cells or platelets.
B-some female patients suffering from recurrent miscarriage as a result
the composition of types of antibodies in the blood.
There are other symptoms such as mental disorders or convulsions when the
disease affects the nervous system but these symptoms are a small percentage of
patients and the majority of patients suffering from symptoms are not severe and
live a normal life, but they require regular follow-up by specialists.
other SymptomS:
Some patientS their infection are diScovered in the
Work of lab analySiS and ShoWS :
10. dieSeS may found aS
1. butterfly rash:
A red rash affecting cheeks and extends across the top of the nose – bone Part.
2. Sensitive skin photosynthesis:
A severe reaction to the skin when exposed to sunlight and usually includes
only the exposed parts of the skin with the safety of the parts covered.
11. 3. Discoid-lupus:
A circular rash, prominent Odhu peel and appears on the face, scalp, ears, chest and
arms.
When cure this rash usually leaves a scar on the skin.
This type of skin rash seen in dark-skinned children compared to other races.
4. Mucosal ulcers
They show small ulcers in the mouth, nose, and usually without pain, sores, but the
nose may cause bleeding nasally.
12. 5. Arthritis:
Appears in the majority of patients, causing pain and swelling in the joints of
the hands or wrists, elbows, knees or other joints in the arms and legs.
Raymonds-fingers-in-SLE
6. Serous inflammation of the membranes: as inflammation of the
pericardium and Pleuritis
13. 7- Kidney disease
the affect in most of patients, but ranges from simple inflammation without any
complications to severe inflammation which may lead to renal failure
8- Disease of the nervous system
Include headaches , mental illness , difficulty concentrating and confusion
9- Disorders of blood cells
is caused by autoimmune antibodies that attack the blood cells
•Red blood cells (hemolytic anemia)
•White blood cells was not serious in this disease usually.
•Low blood platelets may cause bruising or bleeding skin in the different organs
10- Immune disorders:
A - antibodies to DNA RNA): They are directed against the genetic material in cells)
B - antibodies to Smith : (It was called as the first patient with this disease)
found these antibodies in the blood is very accurate in the diagnosis of this
disease does not exist in any other disease.
C- present of antiphospholipid antibodies
11-Antinuclear antibodies.
found in almost all patients with lupus, but they may are found in about 5% of
healthy children.
14. SLE and prEgnancy
•On the other hand there is a type of antibody may be transmitted from
mother to fetus through the placenta, which could cause some health
problems for the child at birth
•the disease may activate and affect the parts of the body during pregnancy or the
period after the birth.
•We recommend that a patient lupus should avoid pregnancy during the disease
activity and that is not pregnancy only after a period of from the recession of the
disease and subject the patient to follow-up to minute during pregnancy.
•studies have shown that most cases of pregnancy in patients with lupus running
normally and the birth of a natural, if subjected to follow-up and treatment required.
15. MEthodS of trEatMEnt
Steroid is most widely used around the world for the treatment of this
disease include( NSAID) Non-steroidal anti-inflammatory drugs
As for treatment, it varies depending on the severity of the disease
and its impact on the body, in many cases may not require the patient
to more than anti-inflammatories and painkillers and some
antihypertensive medications for the immunity in some cases may be
chemotherapy in addition to antimalarials, which are used in most
cases, the doctor is the best who decides when and how to use these
drugs .