Mark Kilgard's presentation at the Singapore Expo on November 29, 2012, focused on the advancements in OpenGL 4.3 and its importance for NVIDIA's Quadro and GeForce GPUs, particularly emphasizing compute shaders and bindless graphics. The talk highlighted several new features in OpenGL 4.3, including real-time global illumination, improved graphics pipelines, and cross-platform capabilities, while also celebrating the 20-year legacy of OpenGL as an open industry standard. Attendees learned how to leverage these advancements for enhanced graphics application performance and work with modern OpenGL functionalities.