This document discusses safe practices for managing sharps in healthcare settings. It defines sharps as needles, blades, and other instruments that can cut or pierce skin. Injuries from sharps often occur during procedures when equipment is passed between workers, during recapping of needles, or from sharps left in unintended places. The document recommends eliminating or reducing sharps use when possible. It also provides guidance on using safety-engineered devices, safe practices during injections and procedures, careful clean up and disposal of sharps, and responding appropriately to sharps injuries. The overall message is that adhering to safe sharps handling practices and policies can help prevent injuries for healthcare workers.