Kattareeya Prompreing
白雅欣
iD:DA61G209
(Student in Ph.D. Business and Management, College Business, STUST
email:da61g209@stust.edu.tw
: katt.rmutl@gmail.com
Kattareeya Prompreing
白雅欣
iD:DA61G209
(Student in Ph.D. Business and Management, College Business, STUST
email:da61g209@stust.edu.tw
: katt.rmutl@gmail.com
Discovery of Production Processes - TutorialDafna Levy
The attached demonstration includes some of the treasures which can be revealed by those who record their production data, and instructions for taking a self test-drive with Disco, a process mining tool of Fluxicon.
Predictive analytics can take you from guesswork to prediction by showing you where you are now, and where you can go next. It empowers you to analyze trends, patterns and relationships in your structured and unstructured data, apply those insights to predict future events, and act to achieve your desired outcomes.
Inventory Management. Dr. Arindam Maiti.pptxarindammaiti9
This is a slide presentation showing Inventory, Inventory control, Inventory management, and the different ways of Inventory management in a healthcare system, government hospital and private hospitals. This slide will also give an idea about the different types of stocks in a hospital or a healthcare facilities and the ways to handling them.
hey friends, we know from earlier research that material control is the major component of cost. so, let us have a look at few tenchniques relating to material control
Operations management is an area of management concerned with designing and controlling the process of production and redesigning business operations in the production of goods or services.
Product Management- Inventroy Management and Controls.pptxRAHUL PAL
In manufacturing operations, production management includes responsibility for product and process design, planning and control issues involving capacity and quality, and organization and supervision of the workforce.
Production management aims to monitor and improve the efficiency of activities, materials, staff resources, and budgets to produce goods. Production outcomes vary according to the industry. A production manager ensures that manufacturing stays on schedule, within budget, and achieves the desired output goals.
Product Management: Inventory Management and Controls.pdfPrachi Pandey
Product management in the pharmaceutical industry plays a vital role in all 4 phases of the product life cycle. It is responsible for the top line (gross revenue generation) along with the sales team and bottom line (EBITA which is revenue before interest, taxes, depreciation, and amortization) targets of a pharmaceutical organization.
Every organization needs inventory for smooth running of its activities. It serves as a link between production and distribution processes. The investment in inventories constitutes the most significant part of current assets and working capital in most of the undertakings. Thus, it is very essential to have proper control and management of inventories. The purpose of inventory management is to ensure availability of materials in sufficient quantity as and when required and also to minimize investment in inventories. So, in order to understand the nature of inventory management of the organization, in this project we analyzing different inventory control techniques for efficient inventory management system.
UNIT – V : HUMAN PHYSIOLOGY
CHAPTER 20: LOCOMOTION AND MOVEMENT
Types of movement- ciliary, fiagellar, muscular; Skeletal muscle- contractile proteins and musclecontraction; Skeletal system and its functions (To be dealt with the relevant practical of Practical syllabus); Joints; Disorders of muscular and skeletal system-Myasthenia gravis, Tetany, Muscular dystrophy, Arthritis, Osteoporosis, Gout.
UNIT – V : HUMAN PHYSIOLOGY
CHAPTER 17 : BREATHING AND EXCHANGE OF GASES part 1
Human Respiratory System The Mechanism of Breathing Transport of Oxygen,
Regulation of Respiration
Chapter 17 breathing & exchange of gases (repaired) (2)Kailash Vilegave
UNIT – V : HUMAN PHYSIOLOGYCHAPTER 17 : BREATHING AND EXCHANGE OF GASES
Respiratory organs in animals (recall only); Respiratory system in humans; Mechanism of breathingand its regulation in humans-Exchange of gases, transport of gases and regulation of respiration Respiratory volumes; Disorders related to respiration-Asthma, Emphysema, Occupational respiratory disorders.
UNIT – IV : PLANT PHYSIOLOGY
CHAPTER 14 : RESPIRATION IN PLANTS.
Exchange gases; Cellular respiration-glycolysis, fermentation (anaerobic), TCA cycle and electron transport system (aerobic); Energy relations-Number of ATP molecules generated; Amphibolic pathways; Respiratory quotient.
Introduction
History
Why parenteral?
Necessary condition of parenteral
advantages/ disadvantages
Methods of preparation
Quality control
Packaging
Types of parenteral products
Routes of administration
advantages/ disadvantages
conclusion
Kailash vilegave
Kingdom Plantae presented by Vrushali Gharat to Mr. Kailash vilegaveKailash Vilegave
Classification Of Kingdom Plantae, Classification Of Kingdom Plantae, Economic importance Algae.
Ulothrix
Reproduction
Mosses and Liverwort
life cycle of all plants.
Osmotic drug delivery system by Mr. kailash vilegaveKailash Vilegave
INTRODUCTION
ADVANTAGES OF OSMOTIC DRUG DELIVERY SYSTEM
DISADVANTAGES OF OSMOTIC DRUG DELIVERY SYSTEM
REPORTED CASES REGARDING LIMITATIONS AND ADVERSE EFFECTS OF OSMOTIC DRUG DELIVERY SYSTEM
PRINCIPLE OF OSMOSIS
BASIC COMPONENTS OF OSMOTIC PUMP
2. INVENTORY MANAGEMENT
It may be defined as a Scientific method of finding out how much stock
should be maintained in order to meet the production demands and be
able
to provide right type of materials at right time, in right quantities and at
competitive prices.
It is actually money which is available in the shape of materials (raw
materials and finished products), equipment, storage space, work time
etc. it also includes intrest on money invested.
input inventory output
material (money) production dept
management - goods in stores
-work in progress
- finished products
- equipment etc.
2
3. INVENTORY CONTROL
It can be defined as “ systematic control and regulation of purchase,
storage and usage of materials in such a way that so as to maintain an
even flow of production, at the same time avoiding excessive investment
in inventories. Efficient inventory control cuts out losses and wastes of
materials.
AIMS OF INVENTORY CONTROL
Never run out of stock of any material .
Never build up very large inventory .
Never send out too many small orders for more as such small order turn
out to be very costly.
3
4. Objectives of inventory control
Utilising capital and investment judiciously.
Keeping the production on as on going basis.
Preventing the idleness of men , machine and morale.
Avoiding risk of loss of life.
Proper quality.
Economy in purchasing.
Minimum wastage.
No-understocking and No-overstocking.
Inducing confidence in customers and to create trust and faith.
4
5. Advantages of Inventory Control
1. To ensure continuous production by supplying material .
2. It helps the concerned to secure many economics through bulk purchase
such as low freight, higher discount, lower price, better use of available
resource etc.
3. It ensures timely and continuous supply of goods to customers by
maintaining sufficient stock of finished goods.
5. It eliminates overstocking of the inventories and maintain minimum
investment .
6. It helps in optimum utilization of men, money, material, equipments,
time and thereby reduce the total cost of the production.
5
6. INVENTORY CATEGORIES
1] Production Inventories :
- materials used are chemicals such as active ingredients and excipients
needed to manufacture finished products, i.e, dosage forms.
eg: equipment containers, labels, caps and shippers needed for pkg of
dosage forms.
2] MRO Inventories ( Maintenance, Repair, and Operating ) :
- parts or sub assemblies needed for final assembly of the end product.
eg: packing of bulk tablets such as strip packing and blister packing.
3] WIP Inventories (Work In Process) :
- items on which work is to be done further. They are semi finished
goods.
eg: granules waiting for compression and tablets waiting for coating.
4] Finished good inventories :
eg: dosage forms, bulk drugs, Physician’s samples etc.
6
7. FACTORS INFLUENCING INVENTORY
Manufacture process requires relatively long process cycle-time.
Procurement of materials has long lead time.
Demand for finished products is some time seasonal and prone to
fluctuations.
Material costs are affected by fluctuations in demand and
subsequently by fluctuations in manufacturing.
These conditions are managed by maintaining reserve stock or safety
stock.
7
8. SELECTIVE INVENTORY CONTROL
Selective inventory control is defined as process of classifying items into
different categories and thereby directing appropriate attention to the
materials.
It is based on the principle of ‘Vital few and trivial many’ made by Pareto.
CLASSIFICATION
1. A-B-C technique
2. V-E-D classification
3. H-M-L ’’
4. F-S-N ’’
5. S-D-E ’’
6. S-O-S ’’
7. G-O-L-F ’’
8. X-Y-Z ’’
8
9. A-B-C Classification
(Always Better Control)
In this technique materials are analyzed according to their value so that
costly and more valuable materials are given greater attention and care.
They are classified acc. to their high, medium, and low, which are known
as A, B and C items respectively.
1. A-items : - Costly items
- Constitute not more than 10% of the total items, but these
consume about 70% of the total budget of inventory.
- Require proper storage and handling
- Overstocking is avoided.
2. B-items : - Neither costly nor cheap.
- Constitute 20% of the total items and consume about 20%
of the total inventory budget.
- Need moderate control. 9
10. 3. C-items : - cheaper
- constitute 70% of the total items and consume about 10% of
total inventory budget on them.
- do not need any control and are given least attention.
10
11. V-E-D Classification
(Vital, Essential and Desirable)
V-Vital : items without which the activities will come to halt.
eg: adrenaline injection, steroid preparations .
E-Essential : items which are likely to coz disruption of the normal
activity.
eg: life supporting items such as transfusion fluids.
D-Desirable : in the absence of which the hospital work does not get
hampered.
eg: aspirin, other analgesics, vitamins, enzymes.
11
12. H-M-L Classification
(High, Medium, Low)
It is based on the unit value (in rupees) of items. The items should be
listed in decreasing order of unit value and management may fix limits
for deciding the three categories.
F-S-N Classification
(Fast, Slow and Non moving)
It takes into account the distribution and handling patterns of items from
stores.
Used when obsolescence is to be controlled.
May be a change in technology or an item is no longer in use. At such
time information must ne given to managers so that they can act on it.
12
13. S-D-E Classification
Its based on lead time analysis and availability.
S- Scarce : longer lead- time (imported).
D- Difficult : long lead -time (indigenous).
E-Easy : reasonable lead- time.
S-O-S Classification
Items which are seasonal in nature and hence require special purchasing
and stocking categories.
G-O-L-F Classification
It stands for Government, Ordinary, Local, Foreign.
13
14. X-Y-Z Classification
It is based on value of inventory stored. If the values are high, special
efforts should be made to reduce them. It is done once in a year.
14
15. Lead times, Stockouts, Safety
stocks
Maximum quantity : upper limit of inventory in the stores.
Minimum quantity : lower limit of the inventory in the stores.
Standard order : it is the difference between maximum and minimum
quantities.
Reorder point : it is the time to initiate a purchase order. If it is not done,
inventory may exhaust and even the reserve stock will be
utilized before the arrival of new items.
Stock holding : it is the buffer stock that should be available to avoid
break
down of production schedule.
15
16. LEAD TIME
It is the time lapse between placement of an order and receipt of items
including their approval by Q.C dept.
It may be calculated on the basis of past experience.
Reasons for the lead time may be explained as internal-external-internal.
•Raising of purchase requisition.
•Inquiries.
•Tenders. Internal
•Scrutiny and approval.
Lead time
•Placement of orders to suppliers.
•Suppliers makes goods ready.
•Transportation and clearing. External
Receiving of goods at stores.
Taking the stock.
Inspection for quantity and quality.
Internal
Ready for issue to production.
16
17. STOCK-OUTS
Means running out of stocks which leads to back orders.
Limits of the stock outs should not be more than 2%.
CAUSES FOR STOCK-OUTS
1] INTERNAL 2] EXTERNAL
- Faulty planning. - Labour problems
- Poor control - Poor selection of transportation
- Improper records - Change in market situations and demand
- Shortage of funds - Floods, Strikes and Fire etc.
- Poor follow-up
- Strikes etc.
17
18. IMPLICATIONS OF STOCK-OUTS
Loss of sales and customers.
Loss of good will and image.
Decreased use of machine and decreased productivity.
Inter-departmental conflict.
Loss of morale.
Emergency purchases at high costs.
18
19. In order to maintain inventory control, it is imp to decide upon various levels
of materials. These are:
Maximum stock level: It’s the upper limit beyond which the qty of
any item is not allowed to rise.The max stock level is fixed after considering
several points.
1. Rate of consumption of material.
2. Amt of capital needed and available.
3. Nature of material.
4. Market trend.
5. Fashion habits.
6. Govt restrictions.
7. Risk involved due to fire, obsolescence and deterioration.
19
20. Minimum stock level/safety stock: its the lower limit below
which the stock of any item should not normally be allowed to fall.
The main purpose of determination of this limit is to protect against the
possibility of particular item going out of stock and there is further
danger of stoppage of its production and supplies.
The level is fixed taking into consideration:
1. Avg rate of consumption.
2. Lead-time.
Re-order level: its fixed between the minimum and maximum stock
level. when the stock of inventory reaches at this point, the process for
the purchase material should be started. Re-order level is slightly more
than min stock level to guard against:
1. Abnormal use of item.
2. Abnormal delay in supply.
20
21. Danger level: this is generally below the minimum stock level. If it reaches
this level, urgent action must be taken to prevent the stock-out.
21
22. SAFETY-STOCKS
Safety stock or buffer stock is an ideal quantity of materials that has been always
maintained and is drawn only in emergency condition.
It is considered as tied-up capital. Hence efforts must be made to keep them at he lowest
level.
ADVANTAGES
1] Allow continuation of the production to certain extent even after the lead time lapses.
2] Uncertain consumption and fluctuating demands can be absorbed.
3] Back orders can be kept to a minimum.
4] Best level of customer service can be achieved.
For A-items : 15 days Vital items : more in quantity
B-items : 30 days Scarce items : ’’
C-items : 60 days Fast moving items : ’’
22
23. REORDER QUANTITY METHODS
Reorder quantity: is qty of items to be ordered so as to continue
production without any interruptions in the future.
Fixed quantity system
The reorder qty is a fixed one and therefore the time for ordering
varies.
When the stock level drops to a predetermined pt known as reorder
level, then order is placed. Its calculated using EOQ.
Its also calculated as:
Reorder level qty = safety stock + (usage rate x lead time)
This eqn. is used to calculate each item independently.
23
24. Open access bin system
The bin is filled with items to the max level as and when required.
These items are used without making a record.
Restricted usually to C-items.
Two bin system
Consists of two bins.
When the first bin is exhausted, it indicates time for reorder. The second
bin is the reserve stock & used during the lead time period.
After receiving the items, items are distributed equally into the two so as
to reach the initial level.
Applicable to hospitals and community pharmacies.
24
25. ECONOMIC LOT SIZE (EOQ) FORMULA
How much of items to buy or order at a time?
When should the items be made available for production?
It is defined as the quantity of the material to be ordered at one time .
This quantity is fixed in such a manner as to minimize the cost of
ordering and carrying the stock so that only correct quantity of the
material is to be purchased .
EOQ EQUATION
Q = 2AS
IU
Q= economic lot size.
A= annual usage units.
S= ordering cost associated with one order, Rs.
I= annual inventory carrying costs expressed as decimal per
unit.
U= Cost of one unit, Rs.
25
26. A & I must be expressed in comparative terms of units writ time and qty.
APPLICATIONS OF EOQ
Good tech for calculating the economical lot size for ordering.
EOQ relationship shows, a general way, how much inventories should be
increased, if the sales of product is increased by 20%.
Acc. to EOQ formula, the max inventory would be square root of 20.
LIMITATIONS
Sometimes, EOQ quantities may not balance with the quantities of all
items needed for a lot size.
Not a time phased procedure.
May not be applicable when demands are irregular and when there is
possibility of price rise.
Inventory holding cost & the ordering cost cannot be identified properly
and calculated accurately.
Proper maintenance of stock records.
Set up cost is also an imp factor. In such cases, a tech called LIMIT( Lot
Size Inventory Management Tech) can be used.
26
27. max inventory level
30 A A’ inventory consumption
25
Inventory in 1000
20
reorder quantity
units
15 BC B’
D
10
minimum inventory level
B’ C’ D’ safety stock
0
R-P Time in weeks
30
L
27
29. COSTS INVOLVED IN EOQ
PROCUREMENT COST: consists of expenditure connected with following,
Receiving quotations
Processing purchase requisition
Receiving and inspecting the items
Processing vendor’s invoice
Procurement cost decreases as order qty increases, bcoz fewer orders
are possible
CARRYING COST: contains of expenditure connected with the following.
Interest on capital investment
Cost of storage facility, up-keep of material, record keeping etc.
Cost involving deterioration
Cost of insurance, property tax etc.
Carrying cost varies with the qty ordered. If smaller is the order,
carrying cost is reduced. In such cases, number of orders increases.
29
30. Relationship between cost and quantity.
50
t
ost
os
40 ing c
Cost per period
lc
y
Carr
ta
To
30
Min
20 cost
10
EOQ Procuring costs
100 200 300 400 500
Order quantity
30
31. REORDER TIME METHODS
They are based on past experience on fixed lead times. Some of these are:
1. Intuitive method
Maintenance of a want book.
Applicable to small pharmacies.
2. Systematic want-book system
Want-books are maintained for each product and each major wholesaler.
Attachment of a card to a product.
Small pharmacies.
3. Fixed interval system
Items are ordered at regular intervals.
4. S & S method
Max stock and reorder levels are predetermined.
5. Single order and scheduled part delivery
Annual requirements are included in single contract.
Specified quantities are delivered in scheduled times.
Ideal for items which are used in small quantities, but at regular rate of
usage.
31
32. MODERN INVENTORY SYSTEMS
1. Material Requirement Planning (MRP)
It’s a computational tech that converts the master-schedule of
production into a detailed schedule for materials and components used
in production.
MRP determines the qty of materials and the date on which these are
needed for each phase of production.
Its based on the principles if independent and dependent demand.
ADVANTAGES
1] Useful when there is sudden change in demand(mkt/qty/date).
2] Minimises unnecessary inventory investment.
3] Machines and material utilizaton can be planned in a better manner and
greater productivity can be achieved.
4] Sophisticated and nature approach of inventory control.
5] Improved customer services.
32
33. DISADVANTAGES
1] High procurement costs bcoz each item is processed seperately.
2] Close monitoring of the material stocks is essential.
METHOD
In MRP systems, 3 sources (files) are required as an input data for
computations.
a) Master production schedule
b) Bill of material file
c) Inventory record file
33
34. 1. MASTER PRODUCTION SCHEDULE FILE
It is a statement of time phased plan for the total production activities .
It is translated to the specific products .
For the product , the components and the quantities are listed .
The production cycle and the production schedule are generated in
stages and includes products likely to go in the shipment .
Material requirement can be broken in terms of weeks and days .
Smaller the time period, the more effective the material plan will be.
34
35. 2. BILLS-OF MATERIALS FILE
It represents the actual flow of production in terms of the quantities
to be packed .
It determines the quantity of the packing component and the bulk
drugs that are needed and is known as the parts list .
The stages and the proper sequence through which the product is
made is determined .
The production and planning department uses BOM to calculate no
of components.
35
36. 3.INVENTORY RECORD FILE
Ordering of items at one time is not correct as different substances
have different lead times . The computers are thus used for this
purpose .
The lead time are obtained as follows .
1. Ordering lead times is obtained from the purchase records .
2. Manufacture route time is obtained from the process route sheets.
36
37. Sales
forecast
Service parts
Customer
requirement
order
Master
Engineering Production Inventory
Schedule file transaction
changes
Bills of MRP
Materials processor Inventory
file Record file
Output
reports
37
38. 2.MANUFACTURING RESOURCE PLANNING
(MRP-II)
It refers to the strategic financial planning as well as production
planning through the use of the simulation capabilities.
It is originally developed for the material orders .
Planning and production are integrated with MRP.
It is a totally company system in which functional group interact and
make joint decisions
It includes monitoring inventory level , work force levels .
38
39. 3. JUST IN TIME(JIT)
It is the process of receiving the material, transforming them into parts,
converting the material into sub assemblies, assemblies and the finished
products for sale.
Product supply is matched with the market demand.
It is an attempt to reduce the working capital to the minimum.
ADVANTAGES
Employees are motivated and better quality of the goods are produced.
Inventory levels are reduced and buffer stocks are also reduced .
Additional stock buying is not required
39
40. NEEDS OF JIT
The main need of the JIT is the motivation factor .
Motivation is for the following types
1. Motivation for control.
2. Motivation for the involvement .
3. Motivation for improvement .
40
41. COSTS AND SAVINGS IN INVENTORY
1] ORDERING COSTS:
Stationary
Clerical and processing, salaries/ rentals
Postage
Processing of bills
Receiving/inspection/documentation
2] HOLDING/ CARRYING COSTS:
Storage space
Property tax on warehousing
Insurance
Deterioration/obsolescence
Material handling and maintenance, equipments.
Q.C
41
42. 3] STOCK OUT COSTS
Loss of business/profit/market/advice.
Additional expenditure due to urgency of purchase.
Telephone charges.
Loss of labour hours.
Air transport charges.
42
43. SAVINGS
Savings are affected by various means:
1. Material substitution
2. Reduction in inventory levels.
3. Variety reduction.
4. Standardization.
43
44. REFERENCES
Pharmaceutical Production and Management by CVS
Subramanyam. Page:292-320.
Drug Store and Business Management by R.M. Mehta.
Page:80-93.
The Theory and Practice of Industrial Pharmacy by
Leon Lachman.
Internet source.
44