Stoichiometry involves calculating the amounts of substances involved in chemical reactions using properties like atomic mass, average atomic mass, moles, and Avogadro's number. Atomic mass is the mass of a single atom expressed in atomic mass units, while average atomic mass takes into account the relative abundances of isotopes. The mole is used to express amounts of substances and tells you how many representative particles like atoms or molecules there are. One mole contains 6.02 x 1023 particles, known as Avogadro's number.