PHYSIOTHERAPY IN HEART TRANSPLANTATION..AneriPatwari
This power point throws the light on Heart transplantation.
it will inform about the indications and contraindication of heart transplant.
It will tell you about the donor selection & donor-recipient matching for heart transplantation.
It will enhance the knowledge of types and complications of heart transplantation.
It will feed the need of assessment and management of heart transplant pre and post-off
It will give the information about physiotherapy assessment pre and post surgery for heart transplantation.
It will lighten the side of physiotherapy management for heart transplantation.
PHYSIOTHERAPY IN HEART TRANSPLANTATION..AneriPatwari
This power point throws the light on Heart transplantation.
it will inform about the indications and contraindication of heart transplant.
It will tell you about the donor selection & donor-recipient matching for heart transplantation.
It will enhance the knowledge of types and complications of heart transplantation.
It will feed the need of assessment and management of heart transplant pre and post-off
It will give the information about physiotherapy assessment pre and post surgery for heart transplantation.
It will lighten the side of physiotherapy management for heart transplantation.
This presentation will throw the light on cardiac physiotherapy rehab after surgery.
This presentation will give the information about definition, center & core team members of cardiac rehab.
This presentation will aware you about core components & training principles of cardiac rehabilitation.
This will inform you about the phases of cardiac physiotherapy rehab after surgery, which also includes weight & nutritional management also behavioral modification & tobacco & smoking cessation with psychological management.
This powerpont will inform about the chest PNF with its definition, principles,aims, indications & contraindications and its effects.
It will lighten up the knowledge of techniques of chest PNF with its observatory findings and its mechanism
Shoulder Pain Relief: Common Rotator Cuff Injuries & Treatment Options - And...Summit Health
If you are experiencing shoulder pain, a rotator cuff tear could be the issue. Learn about how, and why, rotator cuff tears happen, how the condition and severity is diagnosed, and the non-surgical and surgical treatment options available.
This presentation will throw the light on cardiac physiotherapy rehab after surgery.
This presentation will give the information about definition, center & core team members of cardiac rehab.
This presentation will aware you about core components & training principles of cardiac rehabilitation.
This will inform you about the phases of cardiac physiotherapy rehab after surgery, which also includes weight & nutritional management also behavioral modification & tobacco & smoking cessation with psychological management.
This powerpont will inform about the chest PNF with its definition, principles,aims, indications & contraindications and its effects.
It will lighten up the knowledge of techniques of chest PNF with its observatory findings and its mechanism
Shoulder Pain Relief: Common Rotator Cuff Injuries & Treatment Options - And...Summit Health
If you are experiencing shoulder pain, a rotator cuff tear could be the issue. Learn about how, and why, rotator cuff tears happen, how the condition and severity is diagnosed, and the non-surgical and surgical treatment options available.
This lecture give us an understanding about the pathway of the peripheral nerves that emerges from the brachial and cervical plexus. I also discuss about the motor and cutaneous innervation from these nerves and also some condition relate to peripheral nerve injury.
The radial nerve is a continuation of posterior cord of brachial plexus in the axilla. It is the largest nerve of the brachial plexus. It supplies the posterior ( extensor) compartment of upper limb. It carries fibers from all the roots of ( C5,C6,C7,C8 and T1) of the brachial plexus. Allows you to move muscles and feel skin sensation in certain parts of the upper limb. Symptoms of radial nerve injury may include pain, numbness, and/or paresthasia especially in the middles finger, index finger , thumb , back of the hand and /or arm.
Above power point wil give detailed explanation aboutthe cubital fossa.knowledge of this cubital fossa is clinically very important for all clinicians.
This presentation will give orientation to the basic anatomy of liver. The segmental anatomy of liver will give strong and basic anatomy knowledge to surgeons.
posterior abdominal wall is very important structure in abdomen.in this presentation we have to see detailed about posterior abdominal wall muscles .lumbar plexus and nerve supply of posterior abdominal wall .including autonomic sympathetic chain.
posterior abdominal wall is most important chapter in undergraduate curriculum.After read the above presentation you have to able describe about posterior abdominal wall structures like Muscles ,Bony part and Ligamental part. Then nervous innervation of Lumbarplexus and Autonomic nervous system of posterior abdominal wall including sympathetic chain
this presentation give detailed information about posterior compartment of arm.After read this presentation you have describe about muscles of posterior compartment of arm and blood supply and nervous innervation , action of posterior compartment.Also clinical importance of posterior compartment
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Learning objectives
–The applied anatomy of the radial
nerve
–Its anatomical course,
–Motor functions and
–Cutaneous innervation.
–The clinical correlations of damage to
the radial nerve.
3. The radial nerve
• The radial nerve is a continuation of
posterior cord of brachial plexus in the axilla.
• It is the largest nerve of the brachial plexus.
• It supplies the posterior (extensor)
compartment of upper limb.
• It carries fibres from all the roots (C5, C6, C7,
C8, and Tl) of brachial plexus
– (but T1 fibres are not constant).
4.
5.
6.
7. COURSE IN THE AXILLA
• The radial nerve lies posterior to the
third part of the axillary artery and
anterior to the muscles forming the
posterior wall of the axilla.
• Here it gives off the following
three branches:
1. Posterior cutaneous nerve of arm
2. Nerve to the long head of triceps.
3. Nerve to the medial head of triceps.
11. COURSE IN THE ARM
• Radial nerve enters the arm at the
lower border of the teres major.
• It passes between the long and
medial heads of triceps to enter the
lower triangular space, through
which it reaches the spiral groove
along with profunda brachii artery.
12. COURSE IN
SPIRAL GROOVE
• The radial nerve in the spiral groove lies in direct
contact with the humerus.
• At the lower 3rd of the humerus, it pierces the
lateral intermuscular septum to enter anterior
part of the arm again where it lies deeply in the
interval between the brachialis & the
brachioradialis.
• Then between brachialis and extensor carpi
radialis longus before entering the cubital fossa.
13.
14. BRANCHES OF THE RADIAL NERVE
IN SPIRAL GROOVE
• Lower lateral cutaneous nerve of the arm:
– provides sensory innervation to the skin on the lateral
surface of the arm up to the elbow.
• Posterior cutaneous nerve of the forearm:
– Provides sensory innervation to the skin down the middle of
the back of the forearm up to the wrist.
• Nerve to lateral head of triceps.
• Nerve to medial head of triceps.
• Nerve to anconeus (it runs through the substance of
medial head of triceps to reach the anconeus).
• At the lower end of the spiral groove, the radial nerve pierces the
lateral muscular septum of the arm and enters the anterior
compartment of the arm.
15.
16. BOUNDARIES OF THE SPIRAL GROOVE
Anteriorly Middle one-third of the shaft of the
humerus
Above Origin of the lateral head of triceps
Below Origin of the medial head of triceps
Posteriorly Fibres of lateral and long head triceps
17. BRANCHES OF THE RADIAL NERVE
IN THE ANTERIOR COMPARTMENT OF ARM
• The deep branch (also called posterior interosseous
nerve), in the cubital fossa supplies two muscles:
– Extensor carpi radialis brevis.
– Supinator.
• After supplying these two muscles, it passes
through the substance of supinator and enters the
posterior compartment of the forearm and supplies
all the extensor muscles of the forearm.
– It also gives articular branches to the distal radio-ulnar,
wrist, and carpal joints.
18.
19.
20. The radial nerve
• To enter the forearm, the radial nerve moves
anteriorly over the lateral epicondyle of the
humerus.
• Through the cubital fossa.
• It terminates by dividing into two branches:
– Deep branch (motor) called posterior interosseous
nerve:
• Innervates most of the muscles in the posterior compartment
of the forearm.
– Superficial branch (sensory)also called superficial radial
nerve
• Contributes to the cutaneous innervation of the hand and
fingers.
24. The radial nerve
• The superficial branch (also called superficial radial
nerve) is sensory. It runs downwards over the
supinator, pronator teres, and flexor digitorum
superficialis deep to brachioradialis.
– About one-third of the way down the forearm (at about
7 cm above wrist), it passes posteriorly,
• It emerges from under the tendon of
brachioradialis, proximal to the styloid process
of radius and then passes over the tendons of
anatomical snuff-box, where it terminates as
cutaneous branches.
27. Superficial branch of radial nerve
in hand
• It supplies the skin of the lateral (radial) half
of dorsal aspect of the hand and thumb,
• It divides into several dorsal digital nerves
which provide sensory innervation to skin over the
lateral part of the dorsum of hand and dorsal
surfaces of lateral 3 ⅟₂ digits proximal to the nail
beds.
28. What is the radial tunnel?
The radial nervenerve passes down the back of the upper
arm. It then spirals outward and crosses the outside
(the lateral part) of the elbow before it winds its way down
the forearm and hand.
On the lateral part of the elbow, the radial nerve enters a
tunnel formed by muscles and bone. This is called the
radial tunnel.
Passing through the radial tunnel, the radial nerve runs below
the supinator muscle.
– The supinator muscle lets you twist your right hand clockwise.
This is the motion of using a screwdriver to tighten a screw.
29.
30. Radial tunnel syndrome
• It is an entrapment neuropathy of the deep branch of
radial nerve at elbow. The compression of radial nerve
at elbow may be caused by the following four
structures:
1. Fibrous bands, which can tether the radial nerve to
the radio-humeral joint.
2. Sharp tendinous margin of extensor carpi radialis
brevis.
3. Leash of vessels from the radial recurrent artery.
4. Arcade of Frohse, a fibro-aponeurotic proximal edge
of the superficial part of the supinator muscle.
• Characteristic in such cases will be as follows:
– Loss of extension of the wrist and fingers but no wrist drop.
– Pain over the extensor aspect of the forearm.
31. The radial nerve
• Motor Functions
• The radial nerve innervates the muscles located in the
posterior upper arm and posterior forearm.
• In the upper arm, it innervates
– The three heads of the triceps brachii – which acts to extend
the arm at the elbow.
– The brachioradialis and
– Extensor carpi radialis longus (muscles of the posterior
forearm).
• A terminal branch of the radial nerve, the deep
branch, innervates
– The remaining muscles of the posterior forearm
• Note: When the deep branch of the radial nerve penetrates the supinator muscle of the
forearm, it is termed the posterior interosseous nerve for the remainder of its course.
32. The radial nerve
• Sensory Functions
• There are four branches of the radial nerve that provide
cutaneous innervation to the skin of the upper limb.
• Three of these branches arise in the upper arm:
– Lower lateral cutaneous nerve of arm – Innervates the
lateral aspect of the upper arm, below the deltoid muscle.
– Posterior cutaneous nerve of arm – Innervates the posterior
surface of the upper arm.
– Posterior cutaneous nerve of forearm – Innervates a strip of
skin down the middle of the posterior forearm.
• The fourth branch – the superficial branch – is a
terminal division of the radial nerve. It innervates the
dorsal surface of the lateral three and half digits, and
their associated palm area.
33.
34.
35.
36. The radial nerve
• CLINICAL RELEVANCE
• Injuries of the radial nerve: The radial nerve
may be injured at 4 sites:
– (a) in the axilla,
– (b) in the spiral groove,
– (c) in the forearm,
– (d) at the elbow.
37. Lesions of the radial nerve
Lesions Motor deficits Sensory loss
Lesion at the axilla
injured by the pressure
of the upper end of
crutch (crutch palsy),
by a dislocation at the
shoulder joint,
By a fracture of
the proximal humerus.
Triceps weakness
Brachioradialis weakness
Extensor weakness of the
wrist - "wrist drop”
Lateral dorsum of the hand and
wrist
Dorsum of the thumb
Proximal dorsum of fingers
2 and 3
Lesion at the spiral
groove of humerus:
Midshaft fracture of
humerus.
Wrongly placed
intramuscular injection.
Saturday night paralysis.
Triceps is spared!
Brachioradialis weakness
Extensor weakness of the
wrist - "wrist drop”
Lateral dorsum of the hand and
wrist
Dorsum of the thumb
Proximal dorsum of fingers
2 and 3
Lesion at the radial
tunnel
(humeroradial joint)
Extensor weakness of the
wrist - "wrist drop" - may be
mild
Lateral dorsum of the hand and
wrist
Dorsum of the thumb
Proximal dorsum of fingers 2 & 3.