This document discusses quantitative research design and methods. It covers topics such as credibility of research design, sources of variability, design validity, designing quantitative research studies, population and sampling methods, test validity and reliability, threats to internal validity, and subject effects. The overall goal of research design is to provide trustworthy results that approximate reality by controlling sources of error and extraneous variables. Key aspects of design include subjects, instruments, procedures, and treatment administration. Probability and nonprobability sampling techniques are explained.