psychology
introduction to psychology
schools of psychology
scopes of psychology
methods of psychology
relevance of nursing
application of psychology
branches of psychology
evolution of psychology
psychology
introduction to psychology
schools of psychology
scopes of psychology
methods of psychology
relevance of nursing
application of psychology
branches of psychology
evolution of psychology
There are many different ways of thinking about human behavior. Psychologists utilize a variety of perspectives when studying how people think, feel, and behave.
Some researchers focus on one specific perspective, such as the biological perspective, while others take a more eclectic approach that incorporates multiple points of view.
There is no single perspective that is "better" than another;
each simply emphasizes different aspects of human behavior.
Neuroplasticity and the Science of Habit Formation, Case Study ZenFriend.comRemo Uherek
Can we change our brain? Can we re-wire our habits and human patterns? Learn about the Theory & Practice of Habit Change. Why do habits stick? Why not? We will dive into neuroscience and see what this field can teach us.
Is there a scientifically quantifiable effect of meditation? Does the brain change physically after someone meditates for thousands of hours?
What kind of technology can help us shape better habits? What can we learn from the ZenFriend.com case study?
Psychology is an academic and scientific study of mental processes and behavior. Psychologists study such concepts as perception, cognition, emotion, personality, behavior, interpersonal relationships, and the individual and collective unconscious.
Psychology also refers to the application of such knowledge to various spheres of human activity including issues related to daily life—e.g. family, education, and work—and the treatment of mental health problems.
Psychology includes many sub-fields of study and application concerned with such areas as human development, sports, health, industry, media, law.
Psychology is the science of the intellects, characters and behavior of animals including man. Human education is concerned with certain changes in the intellects, characters and behavior of men, its problems being roughly included under these four topics: Aims, materials, means and methods.
Educational psychology is the study of human learning. The study of learning processes, both cognitive and affective, allows researchers to understand individual differences in behavior, personality, intellect, and self- concept. The field of educational psychology heavily relies on testing, measurement, assessment, evaluation, and training to enhance educational activities and learning processes. This can involve studying instructional processes within the classroom setting.
Educational psychology can in part be understood through its relationship with other disciplines. It is informed primarily by psychology, bearing a relationship to that discipline analogous to the relationship between medicine and biology. It is also informed by neuroscience. Educational psychology in turn informs a wide range of specialities within educational studies, including instructional design, educational technology, curriculum development, organizational learning, special education and classroom management. Educational psychology both draws from and contributes to cognitive science and the learning sciences.
Clinical Psychology helps to analyze the human behaviours like mental, emotional and behavioural disorders and diagnose, treat and prevent mental disorders.
Read more: http://www.tauedu.org/school-of-behavioral-science.html
. The extract was again transferred at 70 oC in 1000 ml for another 1 hour and filtered, and then this filtrate was mixed with first filtrate. This filtrate was used for dyeing without any addition of water. The optical density of the filtrate was measured using absorbent type UV-vis spectrophotometer. The optical density of the filtrate was found to be 0.7969 (Tea extract) & 2.235 (Turmeric extract). 4. Dyeing of premordanted bamboo fibres Dyeing conditions used: Dyes used = Turmeric & Tea NaCl = 5 % (owf) Dye concentration = The extracted liquor was used keeping the M :: L ratio at 1 : 30 Temperature = 70 oC Time = 60 min
Colour is most sensitive part of any commodity it enhances the consumer acceptability. It indicates freshness and safety of the food commodity .The demand for natural source of colorant is increasing day by day because of awareness s about the help.
There are many different ways of thinking about human behavior. Psychologists utilize a variety of perspectives when studying how people think, feel, and behave.
Some researchers focus on one specific perspective, such as the biological perspective, while others take a more eclectic approach that incorporates multiple points of view.
There is no single perspective that is "better" than another;
each simply emphasizes different aspects of human behavior.
Neuroplasticity and the Science of Habit Formation, Case Study ZenFriend.comRemo Uherek
Can we change our brain? Can we re-wire our habits and human patterns? Learn about the Theory & Practice of Habit Change. Why do habits stick? Why not? We will dive into neuroscience and see what this field can teach us.
Is there a scientifically quantifiable effect of meditation? Does the brain change physically after someone meditates for thousands of hours?
What kind of technology can help us shape better habits? What can we learn from the ZenFriend.com case study?
Psychology is an academic and scientific study of mental processes and behavior. Psychologists study such concepts as perception, cognition, emotion, personality, behavior, interpersonal relationships, and the individual and collective unconscious.
Psychology also refers to the application of such knowledge to various spheres of human activity including issues related to daily life—e.g. family, education, and work—and the treatment of mental health problems.
Psychology includes many sub-fields of study and application concerned with such areas as human development, sports, health, industry, media, law.
Psychology is the science of the intellects, characters and behavior of animals including man. Human education is concerned with certain changes in the intellects, characters and behavior of men, its problems being roughly included under these four topics: Aims, materials, means and methods.
Educational psychology is the study of human learning. The study of learning processes, both cognitive and affective, allows researchers to understand individual differences in behavior, personality, intellect, and self- concept. The field of educational psychology heavily relies on testing, measurement, assessment, evaluation, and training to enhance educational activities and learning processes. This can involve studying instructional processes within the classroom setting.
Educational psychology can in part be understood through its relationship with other disciplines. It is informed primarily by psychology, bearing a relationship to that discipline analogous to the relationship between medicine and biology. It is also informed by neuroscience. Educational psychology in turn informs a wide range of specialities within educational studies, including instructional design, educational technology, curriculum development, organizational learning, special education and classroom management. Educational psychology both draws from and contributes to cognitive science and the learning sciences.
Clinical Psychology helps to analyze the human behaviours like mental, emotional and behavioural disorders and diagnose, treat and prevent mental disorders.
Read more: http://www.tauedu.org/school-of-behavioral-science.html
. The extract was again transferred at 70 oC in 1000 ml for another 1 hour and filtered, and then this filtrate was mixed with first filtrate. This filtrate was used for dyeing without any addition of water. The optical density of the filtrate was measured using absorbent type UV-vis spectrophotometer. The optical density of the filtrate was found to be 0.7969 (Tea extract) & 2.235 (Turmeric extract). 4. Dyeing of premordanted bamboo fibres Dyeing conditions used: Dyes used = Turmeric & Tea NaCl = 5 % (owf) Dye concentration = The extracted liquor was used keeping the M :: L ratio at 1 : 30 Temperature = 70 oC Time = 60 min
Colour is most sensitive part of any commodity it enhances the consumer acceptability. It indicates freshness and safety of the food commodity .The demand for natural source of colorant is increasing day by day because of awareness s about the help.
The general principle of Agulhon's test is to convert butyric
acid into its copper salt and to extract this with ether. The
copper butyrate imparts a blue color to the ether layer. The
degree of color varies with the concentration of butyrate, the
acidity of the solution and the quantity of copper salt used.
The framework comprises 13 steps that provide the basis for making decisions in relation to the purpose (and objectives), and the available resources, for an inventory.
11. All steps in the Framework are applicable to the planning and implementation of any wetland inventory, and all steps should therefore be followed during the design and planning process. The framework does not provide prescriptive guidance on particular inventory methods; rather it provides guidance to the Contracting Parties and others who are planning to undertake wetland inventory by drawing attention to different methods and wetland classifications already in use and of proven utility under different circumstances.
Tools for target identification and validationDr. sreeremya S
Microarrays
Target identification seeks to identify new targets, normally
proteins (or DNA/RNA), whose modulation might
inhibit or reverse disease progression. Current technologies
enable researchers to attempt to correlate changes in
gene (genomics) and protein (proteomics) expression
with human disease, in the hope of finding new targets.
Microarrays are a well-utilized tool in both academic and
industrial research laboratories. They can be used to
assess gene and protein expression (via nucleic acid or
protein microarrays) to identify novel targets, and can also
be used to validate the found targets at the tissue or cell
scale (via tissue or cell microarrays
A Summary of Computational Social Science - Lecture 8 in Introduction to Comp...Lauri Eloranta
Final lecture of the course CSS01: Introduction to Computational Social Science at the University of Helsinki, Spring 2015.(http://blogs.helsinki.fi/computationalsocialscience/).
Lecturer: Lauri Eloranta
Questions & Comments: https://twitter.com/laurieloranta
Indian Dairy Industry - prepared by Krishna Rathod (PG Institute of Agri-buss...Krishna Rathod
This presentation covers different topics of INDIAN DAIRY INDUSTRY like,Introduction, History, Current status, Opportunities, Constraints, Solution of constraints, SWOT analysis and Conclusion.
Main source of the data and information of this presentation are 'Indian Journal of Applied research, Indian Dairyman, National Dairy Development Board Annual Report 2012-2013, 19th livestock census-2012 all India report, International Journal of Logistic and Supply Chain Management Perspectives'.
A blood clot (thrombus) developed in the circulatory system can cause vascular
blockage leading to serious consequences including death. A healthy hemostatic system
suppresses the development of blood clots in normal circulation, but reacts extensively in
the event of vascular injury to prevent blood loss. Outcomes of a failed hemostasis include
stroke, pulmonary embolism, deep vain thrombosis and acute myocardial infraction
Self-replicating Molecules: An introductionBrian Frezza
A brief Introduction/minireview of self-replicating molecules presented at TSRI Chemistry journal club on 5/11/07.
Most of the description was spoken, so slides may seem sparse without verbal explanation, but I though it was worth sharing anyway.
This file is about the bevioural psychology...fields of psychology and research methods used in psychology....it is very helpful for the beginners who need overview of psychology and its fields...
Are you facing trouble with your Psychology assignments? Then contact My Assignment Services and we assure you that you will not be worried about missing a deadline or not having enough resources to do the assignment on time. Achieve mental peace and relief from all the stress of completing the assignment by our experts who give the best for your highest grade.
For more information related to Psychology Assignment Help, visit us.
Trends in the geometric size and rated power capacity of offshore wind turbines, the main components of an OWT system, encompassing a typical monopile foundation, the substructure, transition piece, the tower, rotor blades and nacelle (hub). Modern OWTs are installed with either pitch-regulated blades or variable rotational speed systems in order to allow optimisation of the power production over a wide range of prevailing wind speeds. The rotational speed of the main rotor shaft is typically between about 10 and 20 rp. Key electromechanical components of the wind turbine, including the gearbox and the generator (Roberts et al.,2007). The gearbox may cause efficiency losses for the wind turbine and is the particular source of the noise. Recent developments in the design of permanent magnet generators have made it possible to construct some types of wind turbines without the requirement for a gearbox. In this case, the rotor is mainly connected directly to a low-speed multi-pole generator that rotates at the same speed, termed the direct-drive unit. Removing the gearbox mainly removes one of the key components requiring more maintenance, and that is mainly prone to failure. This simplification of the mechanical part allows reductions in size and the mass of the nacelle (Gilling, 2009).
The source of energy captured by plants is the sun, which will be the constant source of energy for the next few billion years. The carbon released from the burning of biofuels is continually cycled rather than being released from the ancient fixed carbon sources, as is the case for fossil petroleum and natural gas. The problem is that the cost of the production of fuels from lignocellulose and plant oils is high and this nascent industry cannot compete with the oil prices. Current progress: For the past two decades, ethanol has been synthesized primarily from cornstarch and cane sugar. Fourteen billion gallons of ethanol were synthesized in the USA from cornstarch in 2014. Approximately 40% of the current USA corn crop is availed to produce ethanol and is not likely to expand anymore, because the remainder of the crop is being availed for animal feed and human food. Ethanol is produced from cane sugar in Brazil at a level of 7.2 billion gallons in the year 2014. The renewable energy source is the major terrain to be considered (Sreeremya, 2019).
Agroforestry has a high potential for simultaneously satisfying three important objectives viz., protecting and also stabilizing the ecosystems; producing a high level of output of economic goods; and improving the income and basic materials to the rural population. It has helped in the rehabilitation of the degraded lands on the one hand and has increased farm productivity on the other. At present, agroforestry meets almost half of the demand for fuelwood, 2/3 of the small timber, approx. 70-80 per cent wood for plywood, 60 per cent raw material for paper pulp and approx. 9-11 per cent of the green fodder requirement of livestock, besides meeting the subsistence needs of the households for food, fruit, fiber, medicine etc.
Human population genetics aims to study the population in terms of the genetic variation. This variation can be quantified by determining the gene frequencies of the alleles at segregating loci which mainly characterize one population and distinguish with another. Tasting ability to phenylthiocarbamide (PTC) by an individual is mainly considered as a useful and important tool to study the genetic diversity in the human populations. Taste and smell affects the food preferences and dietary habits, thereby directly influencing the eating behavior of an individual. As taste threshold aggrandizes with age, abnormality in taste function may contribute to the poor dietary intake in the elderly. Bitter taste perception is a conserved the chemical sense against the ingestion of naturally toxic substances in mammals. The experience of the bitterness occurs after certain chemicals contact taste receptors located in cells on the surface of the tongue.
Initial corrosion behavior of element copper in atmospheric environmentDr. sreeremya S
Copper and copper-based alloys encompassing brasses (Cu-Zn) and bronzes (Cu-Sn)are widely used in different industrial and the societal applications. They are common engineering materials in modern architecture and primarily availed for roofing and facade cladding due to their significance of visual appearance (important from an architectural perspective in terms of the design or during renovation of modern or ancient cultural building), ductility, malleability, the atmospheric corrosion resistance and long-term performance. When exposed to air, the copper forms a brownish-green or greenish blue corrosion layer, often denoted as the patina. Copper patina is commonly known as an aesthetically pleasing surface, and one reason for the extensive use of the copper metal and copper-based alloys in both the ancient and modern architecture. One of the most famous examples is the Statue of Liberty in the harbor of the New York, US.
Bronze alloys are the family of copper-based alloys traditionally alloyed with tin. Bronze alloys are of the exceptional historic interest and still finds wide applications.
These approaches encompass new synthesis and processes as well as new tools for instructing aspiring chemists how to do the chemistry in a more environmentally benign manner. The pros to industry as well as the environment are all a part of the positive impact that Green Chemistry is having in the chemistry community and in the society in general. It is important that chemists develop novel Green Chemistry options even on an incremental basis. While all the elements of the lifecycle of a new chemical or process may not be environmentally benign, it is nonetheless pivotal to improve those stages where improvements can be made. The next phase of assessment can then focus on the elements of the lifecycle that are still in need of the improvement. Even though a new Green Chemistry methodology does not solve at once every problem allied with the lifecycle of a particular chemical or process, the advances that it does make are nonetheless very key. Green Chemistry that mainly possesses the spirit of sustainable development was booming in the 1990s
Electron transfer activity of the photosystem II significantly decreased after the exposure of the Chlorella cells to all the six chemicals availed. Lipid peroxidation was slightly reduced by the antioxidant propyl gallate, not changed by indium nitrate and very potently simulated by diethanolamine, chloroquine, sodium monofluoroacetate and the bromobenzene. For five of the chemicals studied (not bromobenzene) there is the very good correlation between the cytotoxic effects in Chlorella cells measured by the algal growth inhibition test, and also the inhibition of photosystem II activity (Chapman et al., 1991). The results suggest that one very key effect of these chemicals in the Chlorella cells is the inhibition of photosynthetic metabolism by the blocking of the photosystem II functionality.
Corona virus was first identified as the cause of the common cold in 1960. In one study carried out in Canada in 2001, more than 510 patients presented with flu-like symptoms. Virological analyses showed that 3.7% of these cases were positive for the HCoV-NL63 strain by polymerase chain reaction (PCR). Until 2002, the corona virus was considered a relatively simple, nonfatal virus; however, an outbreak in 2002–2003 in the Guangdong province in China, which resulted in spread to many other countries, encompassing Thailand, Vietnam, Taiwan, Hong Kong Singapore, and the United States of America, causes severe acute respiratory syndrome (SARS) and high mortality rates in over 1000 -1100 patients.
In the modern times pollution has become the biggest menace for the survival of the biological species. There are different types of pollution e.g. air, water, soil, sound and mental pollution. Earth was the beautiful landscape but man has ruthlessly exploited for his greed specially, in the last century. With sporadic industrialization and random urbanization environmental pollution has become the serious problem. Over exploitation of open spaces, ever-increasing number of automobiles and the demographic pressure has further aggravated the problem. There are different ways and means to mitigate the urban environmental pollution. Plan-ting of trees and the shrubs for abatement of pollution and improvement of environment is a much effective way and well recognized throughout the world. Earlier, the purpose of planting trees in the urban areas was purely aesthetic (Sheldon et al., 1988a). The incessant increase of urban environmental pollution has necessitated to typically reconsider the whole approach of urban landscaping and its orientation in the order to achieve duel effect i.e. bio-aesthetics and mitigation of pollution.
Relation between haemorrhoids and constipationDr. sreeremya S
Patients frequently complain of bleeding with or without the defecation, a swelling, mild discomfort or irritation. Other symptoms may include soilage or the mucous discharge, pruritis, difficulties with the hygiene, and a sense of incomplete evacuation. Internal hemorrhoids are otherwise painless unless they are mainly thrombosed, prolapsed with edema, or strangulated. External hemorrhoids result in pain when the thrombosis occurs and bleeding if ulceration occurs from pressure necrosis. Skin tags may form from the prior acutely edematous or the thrombosed external haemorrhoids (Johanson et al., 1990
Given the rapid aggrandize, it has been postulated the environment has a key role in the causation of obesity. Factors such as the neighborhood-scale features (referred to as the built environment) have been mainly identified as influencing diet and physical activity (2). Of particular the importance to this framework are features of the food environment (FE), thus constituting barriers and opportunities to food sources of the varying nutritional quality and energy density (3). The FE is delineated as the physical presence of food that can mainly influence a person’s diet (4). Contributing to the FE is the proximity to food store locations such as mainly the restaurants (fast-food, full service, and bars and pubs) and the retail outlets (food markets/grocery stores and liquor stores). Fast- food establishments generally have foods of lower nutritional quality and higher caloric density than the home-prepared foods (3). Early studies have reported fast-food restaurants to be more common in the neighborhoods with a higher prevalence of obesity. However, more recent studies have been melanged,
Adverse conditon provided for influenza virus (mutatedDr. sreeremya S
THIS MUTATED INFLUENZA VIRUS CAN BE TREATED IN PH1-2 . TO CHECK THE LYSIS OF THE VIRUS
SIMULATING THE INTERFERON ACTIVITY HAS TO BE DONE SIMULTANEOUSLY.
Although 76-90% of the BMW is non-hazardous and harmless as any of the other municipal waste, the remaining 10-26% is hazardous to humans or animals and deleterious to environment. Inappropriate handling of the BMW may have serious public health consequences and the significant impact on the environment. Major hospitals contribute substantially to the quantum of generation of the BMW. Smaller hospitals, the nursing homes, clinics, the pathological laboratories and blood banks also have major contribution to BMW. The common methods adopted for the BMW disposal are incineration and land filling. However, these methods are mainly considered more expensive and less ecofriendly due to their main negative impact on the environment
Corona virus current scenario (theoretical outlook)Dr. sreeremya S
Corona virus(COVID-19) is RNA virus. Which has proved to be pandemic.It causes respiratory disease called Severe Acute Respiratory Syndrome(SARS). Currently it is a deadly disease which is killing hundreds of people day by day from late 2019 to till date. There is only few studies regarding the corona virus infection in animals. Studies are still progressing to find remedies like variolation, RNA silencing or boosting human interferon’s to decrease the affect of the disease.
INTRODUCTION
As people have seen, the giant industrial wind farms, small household wind turbines, and also everything in between are erecting all over the places. In 2012, the electricity capacity from the wind power in the total electric capacity is about 7.2% in EU, 2.0% in China, and 3.6% in US. Nevertheless, most people agree that wind energy should claim much greater share of the future energy supply. For eg:-, the United States is working on an ambitious target of 21% total electricity capacity by 2030. Indeed, wind energy is one of the fastest growing energy sources today and also in the foreseeable future. However, findings a suitable site to build the wind farm or simply set up the wind turbine is not always easy. The wind must be strong and must be consistent; the tower cannot obstruct the view; and the noise cannot disturb the local residence. Due to the fast growth of the population, it is aggrandizingly difficult to find a suitable place that is proper for a wind turbine yet will not interfere with the people’s everyday life (Srensen et al., 2002).
INTRODUCTION
A lot of basic concepts, technologies and pioneering solutions aiming on very high power densities were mainly developed within the last 20 years. Sometimes this is denoted as the mechatronic system integration or simply as mechatronics. Besides many of the technical aspects, the movings within the value chain represent the great challenge in this process. This is because traditionally defined between electronic device and the power module manufacturers, electronics assemblers, and the metalworking industry will blur or slowly disappear. However, the pressure to go this path increases. If one thinks, e.g., about the hybrid drive as an upgrade option for conventional passenger cars, one is directly faced with the lack of construction space as one of the main serious problems (Alkuhayli et al., 2012).
Pellagra may also occur as the result of a variety of (relatively rare) conditions affecting tryptophan metabolism and as a side-effect of the number of drugs that inhibit tryptophan metabolism. In alcoholics, it is unclear whether pellagra is the result of an impairment of tryptophan and the niacin metabolism directly attributable to alcohol, or whether it reflects general under nutrition among the people who obtain a considerable proportion on their energy needs from alcohol, and hence have the low intake of (nutrient rich) foods(Goldberger et al.,1922a).
SYMPTOMS
The major symptoms of pellagra are dermatitis, dementia, and diarrhea. This is because niacin deficiency is most noticeable in the body parts with high rates of cell turnover, such as the skin or gastrointestinal tract (Goldberger et al., 1923).
The growing interest in the environmental stress has been accompanied by a rapid accumulation of evidence indicating that the environment can elicit substantial stress in people living in urban environments. Furthermore, it is widely conceived that the natural environment can enhance human health. There have been several questionnaire studies and investigations on the psychological effects of forest environments. A previous study found an enhancement of the positive emotions among subjects who were shown pictures of natural environments. Moreover, other researches have also found that forest environments improve the psychological wellbeing of people
As the techniques that have enabled us to analyses and assess a biopsy become ever more sophisticated, we have realised the limitations of looking at the single snap-shot of the tumour. This single-biopsy bias was highlighted in which it was mainly demonstrated that a portion taken from different parts of a primary tumour and its metastases showed and proved extensive intertumoural and intratumoural evolution. This tumoural heterogeneity mainly highlights the difficulty of dictating a therapeutic course of action based on the single biopsy, as it is likely to underestimate the ramification of the genomic landscape of the tumour (Chomczynski et al., 2016).Having established that there is mainly considerable tumour heterogeneity, taking multiple biopsies from the patients‘ primary tumour and the metastases would seem to be the most obvious next step. There are so much difficulties in obtaining the tissue biopsy— including the discomfort suffered by the patient, the inherent clinical risks to the patient
Rivivna humilis berry extract as fungal sourceDr. sreeremya S
The introduction of the mankind had marked the continuous exploitation of the plants as organisms and their products for the pharmacological prospects and key features (Guha et al., 1999). In most of the agronomic domains around the globe, the conventional modes of the treatment are still in exercise and also in upcoming research (Srivastava et al., 2003).
These approaches most commonly exploit the various dynamics and much specific potential and applications of plant extracts (Bonde et al., 2007) . The distinctions of the first and foremost large-scale screening of the green plants evaluate and also assess the antimicrobial activity of 2,300 plants (Nautiyal et al., 1984).
Dyeing is an ancient and traditional art which predates written records. It was practised specifically during the Bronze Age in Europe (Sreeremya, 2016). Conventional dyeing techniques encompassed sticking plants to fabric or rubbing crushed pigments into cloth.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
2. Psychology is an academic and scientific study of mental processes and
behavior. Psychologists study such concepts as perception, cognition,
emotion, personality, behavior, interpersonal relationships, and the
individual and collective unconscious.
Psychology also refers to the application of such knowledge to
various spheres of human activity including issues related to daily life—
e.g. family, education, and work—and the treatment of mental health
problems.
Psychology includes many sub-fields of study and application
concerned with such areas as human development, sports, health,
industry, media, law.
Psychology is the science of the intellects, characters and
behavior of animals including man. Human education is
concerned with certain changes in the intellects, characters and
behavior of men, its problems being roughly included under these
four topics: Aims, materials, means and methods.
3. Psyche = soul, mind.
Logos = word, science, study, discourse.
Psychology as the science of soul.
Psychology as the science of mind.
Psychology as the science of consciousness.
Psychology as the science of behaviour.
By P. Muthupandi.
4. Educational psychology is the study of human learning. The study of
learning processes, both cognitive and affective, allows researchers to
understand individual differences in behavior, personality, intellect, and
self- concept. The field of educational psychology heavily relies on
testing, measurement, assessment, evaluation, and training to enhance
educational activities and learning processes. This can involve studying
instructional processes within the classroom setting.
Educational psychology can in part be understood through its
relationship with other disciplines. It is informed primarily
by psychology, bearing a relationship to that discipline analogous to the
relationship between medicine and biology. It is also informed
by neuroscience. Educational psychology in turn informs a wide range of
specialities within educational studies, including instructional
design, educational technology, curriculum development, organizational
learning, special education and classroom management. Educational
psychology both draws from and contributes to cognitive science and
the learning sciences.
5. W. B. Kolesnik:
“Psychology is the science of human behaviour.”
C.V. Good defines :
“Psychology is the study of adjustments of
organism, especially the human organism to
changing environment.”
By P. Muthupandi.
6. Psychology is a pure science:
It is empirical : experimental.
It is a systematic study.
It uses measurements and
tools of measurement.
It has Definitions of terms.
By P. Muthupandi.
7. Abnormal psychology deals with behaviour disorders and
disturbed individuals. For example, researchers might investigate
the causes of violent or self-destructive behaviour or the
effectiveness of procedures used in treating an emotional
disturbance.
Clinical psychology uses the understandings derived from
developmental and abnormal psychology to diagnose and treat
mental disorders and adjustment problems. Some clinical
psychologists work to develop programmes for the prevention of
emotional illness or conduct basic research on how individuals
can better cope with the problems of daily life.
By P. Muthupandi.
8. Educational psychology attempts to improve teaching methods and materials, to
solve learning problems, and to measure learning ability and educational progress.
Researchers in this field may devise achievement tests, develop and evaluate
teaching methods, or investigate how children learn at different ages.
Industrial psychology is concerned with people at work. Industrial psychologists
investigate such matters as how to make jobs more rewarding or how to improve
workers' performance. They also study personnel selection, leadership, and
management. Organizational psychology is a closely related field.
Social psychology studies the social behaviour of individuals and groups, with
special emphasis on how behaviour is affected by the presence or influence of
other people. Social psychologists concentrate on such processes as
communication, political behaviour, and the formation of attitudes.
By P. Muthupandi.
9. Comparative psychology explores the differences and similarities
in the behaviour of animals of different species. Psychologists in
this field make systematic studies of the abilities, needs, and
activities of various animal species as compared with human
beings.
Developmental psychology studies the emotional, intellectual, and
social changes that occur across the life span of human beings.
Many developmental psychologists specialize in the study of
children or adolescents.
By P. Muthupandi.
10. Thus psychology is an important field of
study,which embrances about the knowledge
on the behavioural and adaptive pattern of
human beings