This document discusses DNA origami, which is the art of folding DNA into designed two-dimensional and three-dimensional shapes without cutting or gluing. It describes using a viral genome as the scaffold and staple strands to fold it into shapes. Pixels can be created by modifying staple strands with tags. The document also discusses designing a DNA box large enough to contain a ribosome and discusses possible cargo. It mentions using a lock and key mechanism and software for designing DNA origami structures. Finally, it discusses potential applications of DNA origami like nanomachines for microsurgery, neuroimaging sensors, and direct cellular interaction.
This document summarizes research on using nanotechnology techniques like thermal induced phase separation (TIPS) to create 3D nanofibrous gelatin scaffolds for tissue engineering applications. The TIPS technique involves dissolving gelatin in a solvent mixture, inducing phase separation at low temperatures, then solvent exchange and freeze-drying to form nanofibrous gelatin matrices. Macroporous gelatin scaffolds were also fabricated by combining TIPS with a porogen leaching method using paraffin spheres. These nanofibrous gelatin scaffolds show potential for tissue engineering due to their ability to mimic the extracellular matrix.
CARBON NANO TUBES IN BIOLOGY AND MEDICINEsathish sak
carbon nano-tubes are rolled up seamless cylinders of graphene sheets, exhibiting unparalleled physical, mechanical, and chemical properties.depending on the number of graphene layers from which a single nano-tubes is composed.
Circular dichroism is the difference in absorption of left and right circularly polarized light by a chiral molecule. It occurs due to interactions between the molecule's chiral chromophores and polarized light. CD spectroscopy is used to analyze the secondary structure of proteins and monitor structural changes. The technique provides structural signatures for alpha helices, beta sheets, and random coils. It is a powerful tool for studying protein folding and structural changes under various conditions.
Protein corona associated with nanoparticlesANJUNITHIKURUP
The document discusses protein coronas that form around nanoparticles when introduced into biological fluids and how they impact physiological response. It summarizes that nanoparticles interact with proteins to form complexes with unique identities compared to the original nanoparticle. These complexes determine responses like uptake, circulation and toxicity. The document then examines several studies that show how nanoparticle properties like size and surface chemistry influence protein adsorption and subsequently impact biological response. It also reviews techniques for characterizing and experimentally investigating protein coronas and their effects.
TOP-DOWN AND BOTTOM-UP APPROACH IN SYNTHESIS OF NANOPARTICLES.pptxLubhanshiRajeshisodi
There are two approaches for the manufacturing of nanomaterials:
The “top-down” approach, which involves the breaking down of large pieces of material to generate the required nanostructures from them.
The “bottom-up” approach, which implies assembling single atoms and molecules into larger nanostructures.
Bottom-Up includes:-
Sol gel method
Template Assisted Synthesis
Chemical Precipitation
Microwave Assisted Synthesis
Self Assembly
Top-Down Includes:-
Mechanical Milling
High Pressure Torsion
Laser Ablation
Chemical Etching
Sputtering
This document discusses DNA origami, which is the art of folding DNA into designed two-dimensional and three-dimensional shapes without cutting or gluing. It describes using a viral genome as the scaffold and staple strands to fold it into shapes. Pixels can be created by modifying staple strands with tags. The document also discusses designing a DNA box large enough to contain a ribosome and discusses possible cargo. It mentions using a lock and key mechanism and software for designing DNA origami structures. Finally, it discusses potential applications of DNA origami like nanomachines for microsurgery, neuroimaging sensors, and direct cellular interaction.
This document summarizes research on using nanotechnology techniques like thermal induced phase separation (TIPS) to create 3D nanofibrous gelatin scaffolds for tissue engineering applications. The TIPS technique involves dissolving gelatin in a solvent mixture, inducing phase separation at low temperatures, then solvent exchange and freeze-drying to form nanofibrous gelatin matrices. Macroporous gelatin scaffolds were also fabricated by combining TIPS with a porogen leaching method using paraffin spheres. These nanofibrous gelatin scaffolds show potential for tissue engineering due to their ability to mimic the extracellular matrix.
CARBON NANO TUBES IN BIOLOGY AND MEDICINEsathish sak
carbon nano-tubes are rolled up seamless cylinders of graphene sheets, exhibiting unparalleled physical, mechanical, and chemical properties.depending on the number of graphene layers from which a single nano-tubes is composed.
Circular dichroism is the difference in absorption of left and right circularly polarized light by a chiral molecule. It occurs due to interactions between the molecule's chiral chromophores and polarized light. CD spectroscopy is used to analyze the secondary structure of proteins and monitor structural changes. The technique provides structural signatures for alpha helices, beta sheets, and random coils. It is a powerful tool for studying protein folding and structural changes under various conditions.
Protein corona associated with nanoparticlesANJUNITHIKURUP
The document discusses protein coronas that form around nanoparticles when introduced into biological fluids and how they impact physiological response. It summarizes that nanoparticles interact with proteins to form complexes with unique identities compared to the original nanoparticle. These complexes determine responses like uptake, circulation and toxicity. The document then examines several studies that show how nanoparticle properties like size and surface chemistry influence protein adsorption and subsequently impact biological response. It also reviews techniques for characterizing and experimentally investigating protein coronas and their effects.
TOP-DOWN AND BOTTOM-UP APPROACH IN SYNTHESIS OF NANOPARTICLES.pptxLubhanshiRajeshisodi
There are two approaches for the manufacturing of nanomaterials:
The “top-down” approach, which involves the breaking down of large pieces of material to generate the required nanostructures from them.
The “bottom-up” approach, which implies assembling single atoms and molecules into larger nanostructures.
Bottom-Up includes:-
Sol gel method
Template Assisted Synthesis
Chemical Precipitation
Microwave Assisted Synthesis
Self Assembly
Top-Down Includes:-
Mechanical Milling
High Pressure Torsion
Laser Ablation
Chemical Etching
Sputtering
This document summarizes self-assembly of DNA structures. It discusses how DNA can be used as a nanoscale building material through sticky ends, branches, and double crossover structures that allow strands to selectively bind. DNA tiles and origami are introduced, where tiles and helper strands are used to form two-dimensional crystalline assemblies and predefined shapes from a long scaffold strand. The ability of DNA to self-assemble through complementary base pairing allows for precise nanostructures to be designed and fabricated from DNA alone.
This document discusses various nanolithography techniques for fabricating nano-scale structures. It introduces nanolithography and defines its terms. It then outlines and describes several key nanolithography methods including photolithography, electron beam lithography, x-ray lithography, nanoimprint lithography, and dip pen nanolithography. Diagrams and figures are included to illustrate the various processes. References are provided at the end.
This document describes research on producing multilayer graphene oxide membranes using different oxidation methods of vein graphite. The objectives were to compare the sp2/sp3 carbon ratios in the resulting graphite oxides. Two methods were used: Hummers' method and an improved Hummers' method. Analysis using SEM, XPS, and carbon/oxygen ratios showed the improved method produced a higher fraction of oxidized carbon with a sp3/sp2 ratio of 3.62:1, compared to 1.04:1 for the standard Hummers' method. This indicates the improved method yields better oxidation of the graphite starting material.
Nanomedicines show promise for improving cancer treatment. Nanoparticles can be engineered to target cancer cells specifically and deliver toxic payloads or heat. Gold nanoparticles activated by laser light can hyperthermically destroy tumor cells from the inside. Challenges remain in developing nanoparticles that are safe and can effectively reach tumors. If these challenges can be addressed, nanomedicine may enable more precise cancer detection and treatments with fewer side effects than conventional therapies.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEMsathish sak
This document discusses how nanoparticles can be used for targeted drug delivery in cancer and inflammation. Nanoparticles less than 100nm in size can be engineered from biodegradable materials to efficiently carry drugs and be taken up by targeted cells. They allow for higher doses of drugs to be delivered directly to diseased cells over prolonged periods of time, reducing side effects. Examples discussed include using nanoparticles to target cancer cells, tumor angiogenesis, infected macrophages, and inflammatory molecules. The future potential of nanotechnology for improved targeted drug delivery is promising.
Biological Synthesis of Copper Nanoparticles and its impact - a Reviewinventionjournals
International Journal of Pharmaceutical Science Invention (IJPSI) is an international journal intended for professionals and researchers in all fields of Pahrmaceutical Science. IJPSI publishes research articles and reviews within the whole field Pharmacy and Pharmaceutical Science, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Circular dichroism spectroscopy measures the differential absorption of left and right circularly polarized light by chiral molecules. When light passes through an optically active substance, the left and right circular polarizations are absorbed to different extents. A CD spectrometer contains a light source, monochromator, polarizer, photoelastic modulator and detector. It measures the CD signal as a function of wavelength, providing information about secondary structure of proteins and nucleic acids. CD spectroscopy requires minimal sample amounts and can quickly analyze secondary structure without crystallization. It is useful for studying protein folding, ligand binding and environmental effects on structure.
Sedimentation for determining molecular weight of macromoleculesShubhangiSuri1
Process of sedimentation with mechanism of action and mathematical derivations, different methods for separation of macromolecules by sedimentation, viscometry vs sedimentation
Applications of nanobiotechnology by kk sahuKAUSHAL SAHU
INTRODUCTION
DEFINITION
HISTORY
NANOSCALE
NANOPARTICLES
NANOBIOTECHNOLOGY
NANOTOOLS
APPLICATIONS
RESEARCH
CONCLUSION
REFRENCES
Nanotechnology is the design, characterization and application of structures, devices and systems by controlling shape and size at the nanometer scale!” defines the Royal Academy of Engineering in London in 2004 .
Concepts that are enhanced through nanobiology include: nanodevices, nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology.
This document discusses DNA-based nanobioelectronics. It begins by introducing DNA and its potential use in nanoelectronics. It then discusses using DNA to template the assembly of metal nanoparticles, as well as using sequence-specific molecular lithography to pattern nanoparticles on DNA. It also discusses using metal nanoparticles for DNA detection and field-effect transistors for label-free electronic DNA detection. The document outlines applications in areas like medical diagnostics, environmental monitoring, and more. It concludes by discussing using DNA derivatives that may have better intrinsic conductivity than DNA.
This document summarizes key differences between prokaryotic and eukaryotic genomes. Prokaryotes like bacteria have circular chromosomes contained in nucleoids without membranes. Their DNA is tightly packed using supercoiling. Eukaryotes have linear chromosomes packaged with histone proteins into nucleosomes, forming chromatin within membrane-bound nuclei. Chromatin is further organized into 30nm fibers.
Plastids are double-membrane organelles found in plant, algae, and some eukaryotic cells that are the site of important chemical compound synthesis and storage. They contain DNA like prokaryotes and exist in various types depending on function and pigment. Chloroplasts in particular originated from endosymbiosis with cyanobacteria and contain genes for photosynthesis. Transplastomic plants are genetically engineered by inserting foreign genes into chloroplast DNA instead of nuclear DNA, preventing pollen gene flow.
Buckminsterfullerene, also known as a buckyball, is a spherical molecule composed of 60 carbon atoms arranged in the shape of a hollow ball. It was discovered in 1985 by British chemist Harry Kroto along with American researchers Richard Smalley and Robert Curl, for which they received the Nobel Prize in Chemistry in 1996. Buckyballs have unusual strength and stability properties and can potentially be used for applications such as drug delivery, hydrogen fuel storage, and photovoltaics. However, they are currently expensive to produce and their main use is currently in scientific research.
Analysis Analysis Analysis Analysisof the entire entire entire protein protein proteinproteincomplementcomplement complement complement of acell, cell, tissue, tissue, tissue, or organism organism organism under under aspecific, specific, specific, defined defined set of conditions conditions conditions .
• Relies Relies Relies on 3basic technological technological technological technological technological cornerstones cornerstones cornerstones cornerstones
• MethodMethod MethodMethod to fractionatefractionate fractionatefractionate fractionatefractionate complexcomplex complex protein/protein/ protein/ protein/ peptide peptide peptidemixturesmixtures mixtures
• MS to acquire acquire the data data necessary necessary to identify identify identifyidentifyindividual individual individual individualproteins proteins
• Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformaticsto analyze analyze and assemble assemble the MS data
Homology modeling is a technique used to predict the 3D structure of a protein from its amino acid sequence by comparing it to proteins with similar sequences whose structures are already known. It involves searching a database for template structures, aligning the target sequence to the template, building a model by transferring 3D coordinates from the template to the target sequence, and validating the resulting model. Homology modeling works best when the sequence identity between the target and template is over 30% since protein structure is more conserved than sequence over evolution.
This document provides an outline of a lecture on the ICAT technique for quantitative proteomics. It begins with definitions of ICAT labeling and terminology used. ICAT labels peptides or proteins at cysteine residues with either light or heavy isotopic tags. The light tag contains hydrogen while the heavy tag contains deuterium. Tagged peptides are then purified using streptavidin affinity chromatography. The document discusses the need for gel-free proteomics due to limitations of gel-based methods. It provides an overview of the ICAT working protocol, which involves labeling proteins or peptides with light and heavy tags, trypsin digestion, affinity purification, and MS analysis to determine expression ratios.
Mapping and quantifying transcripts:
Northern blots
S1 mapping of 5’ and 3’ end transcripts
Primer extension
Runoff transcription and G –less cassette transcription
Nuclear Runon transcription
The document provides an overview of the Human Genome Project (HGP). It describes the HGP's goal of mapping and sequencing the entire human genome. The HGP was an international research effort that worked alongside a private company, Celera Genomics, to complete a rough draft of the human genome by 2000. The completion of the HGP marked a major scientific achievement and has transformed fields like medicine, biotechnology, and genetics by providing a comprehensive map of the human genetic code.
Energy minimization methods - Molecular ModelingChandni Pathak
Methods to minimize the energy of molecules during drug designing - Computational chemistry. According to the PCI syllabus, B.Pharm 8th Sem - Computer-Aided Drug Design (CADD).
This document asks a series of questions to help the reader reflect on their background, values, goals, strengths, communities, past achievements, and desired legacy. It prompts the reader to consider where they come from, what gives them strength, their hopes and dreams, what holds them back, who supports them, what past actions they are proud of, and what kind of legacy they want to leave. The questions are meant to guide self-reflection.
This document provides information about Passover and Ramadan. For Passover, it summarizes the biblical story of Moses being placed in a basket in the Nile river and rescued by Pharaoh's daughter before going on to lead the Israelites out of slavery in Egypt. For Ramadan, it summarizes the story of Muhammad receiving his first revelation from the angel Gabriel during the month of Ramadan in the year 610 CE. It then lists some common practices during Passover like having a seder meal and during Ramadan like fasting and giving charity. It concludes by asking questions about personal and family experiences with the holidays.
This document summarizes self-assembly of DNA structures. It discusses how DNA can be used as a nanoscale building material through sticky ends, branches, and double crossover structures that allow strands to selectively bind. DNA tiles and origami are introduced, where tiles and helper strands are used to form two-dimensional crystalline assemblies and predefined shapes from a long scaffold strand. The ability of DNA to self-assemble through complementary base pairing allows for precise nanostructures to be designed and fabricated from DNA alone.
This document discusses various nanolithography techniques for fabricating nano-scale structures. It introduces nanolithography and defines its terms. It then outlines and describes several key nanolithography methods including photolithography, electron beam lithography, x-ray lithography, nanoimprint lithography, and dip pen nanolithography. Diagrams and figures are included to illustrate the various processes. References are provided at the end.
This document describes research on producing multilayer graphene oxide membranes using different oxidation methods of vein graphite. The objectives were to compare the sp2/sp3 carbon ratios in the resulting graphite oxides. Two methods were used: Hummers' method and an improved Hummers' method. Analysis using SEM, XPS, and carbon/oxygen ratios showed the improved method produced a higher fraction of oxidized carbon with a sp3/sp2 ratio of 3.62:1, compared to 1.04:1 for the standard Hummers' method. This indicates the improved method yields better oxidation of the graphite starting material.
Nanomedicines show promise for improving cancer treatment. Nanoparticles can be engineered to target cancer cells specifically and deliver toxic payloads or heat. Gold nanoparticles activated by laser light can hyperthermically destroy tumor cells from the inside. Challenges remain in developing nanoparticles that are safe and can effectively reach tumors. If these challenges can be addressed, nanomedicine may enable more precise cancer detection and treatments with fewer side effects than conventional therapies.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEMsathish sak
This document discusses how nanoparticles can be used for targeted drug delivery in cancer and inflammation. Nanoparticles less than 100nm in size can be engineered from biodegradable materials to efficiently carry drugs and be taken up by targeted cells. They allow for higher doses of drugs to be delivered directly to diseased cells over prolonged periods of time, reducing side effects. Examples discussed include using nanoparticles to target cancer cells, tumor angiogenesis, infected macrophages, and inflammatory molecules. The future potential of nanotechnology for improved targeted drug delivery is promising.
Biological Synthesis of Copper Nanoparticles and its impact - a Reviewinventionjournals
International Journal of Pharmaceutical Science Invention (IJPSI) is an international journal intended for professionals and researchers in all fields of Pahrmaceutical Science. IJPSI publishes research articles and reviews within the whole field Pharmacy and Pharmaceutical Science, new teaching methods, assessment, validation and the impact of new technologies and it will continue to provide information on the latest trends and developments in this ever-expanding subject. The publications of papers are selected through double peer reviewed to ensure originality, relevance, and readability. The articles published in our journal can be accessed online.
Circular dichroism spectroscopy measures the differential absorption of left and right circularly polarized light by chiral molecules. When light passes through an optically active substance, the left and right circular polarizations are absorbed to different extents. A CD spectrometer contains a light source, monochromator, polarizer, photoelastic modulator and detector. It measures the CD signal as a function of wavelength, providing information about secondary structure of proteins and nucleic acids. CD spectroscopy requires minimal sample amounts and can quickly analyze secondary structure without crystallization. It is useful for studying protein folding, ligand binding and environmental effects on structure.
Sedimentation for determining molecular weight of macromoleculesShubhangiSuri1
Process of sedimentation with mechanism of action and mathematical derivations, different methods for separation of macromolecules by sedimentation, viscometry vs sedimentation
Applications of nanobiotechnology by kk sahuKAUSHAL SAHU
INTRODUCTION
DEFINITION
HISTORY
NANOSCALE
NANOPARTICLES
NANOBIOTECHNOLOGY
NANOTOOLS
APPLICATIONS
RESEARCH
CONCLUSION
REFRENCES
Nanotechnology is the design, characterization and application of structures, devices and systems by controlling shape and size at the nanometer scale!” defines the Royal Academy of Engineering in London in 2004 .
Concepts that are enhanced through nanobiology include: nanodevices, nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology.
This document discusses DNA-based nanobioelectronics. It begins by introducing DNA and its potential use in nanoelectronics. It then discusses using DNA to template the assembly of metal nanoparticles, as well as using sequence-specific molecular lithography to pattern nanoparticles on DNA. It also discusses using metal nanoparticles for DNA detection and field-effect transistors for label-free electronic DNA detection. The document outlines applications in areas like medical diagnostics, environmental monitoring, and more. It concludes by discussing using DNA derivatives that may have better intrinsic conductivity than DNA.
This document summarizes key differences between prokaryotic and eukaryotic genomes. Prokaryotes like bacteria have circular chromosomes contained in nucleoids without membranes. Their DNA is tightly packed using supercoiling. Eukaryotes have linear chromosomes packaged with histone proteins into nucleosomes, forming chromatin within membrane-bound nuclei. Chromatin is further organized into 30nm fibers.
Plastids are double-membrane organelles found in plant, algae, and some eukaryotic cells that are the site of important chemical compound synthesis and storage. They contain DNA like prokaryotes and exist in various types depending on function and pigment. Chloroplasts in particular originated from endosymbiosis with cyanobacteria and contain genes for photosynthesis. Transplastomic plants are genetically engineered by inserting foreign genes into chloroplast DNA instead of nuclear DNA, preventing pollen gene flow.
Buckminsterfullerene, also known as a buckyball, is a spherical molecule composed of 60 carbon atoms arranged in the shape of a hollow ball. It was discovered in 1985 by British chemist Harry Kroto along with American researchers Richard Smalley and Robert Curl, for which they received the Nobel Prize in Chemistry in 1996. Buckyballs have unusual strength and stability properties and can potentially be used for applications such as drug delivery, hydrogen fuel storage, and photovoltaics. However, they are currently expensive to produce and their main use is currently in scientific research.
Analysis Analysis Analysis Analysisof the entire entire entire protein protein proteinproteincomplementcomplement complement complement of acell, cell, tissue, tissue, tissue, or organism organism organism under under aspecific, specific, specific, defined defined set of conditions conditions conditions .
• Relies Relies Relies on 3basic technological technological technological technological technological cornerstones cornerstones cornerstones cornerstones
• MethodMethod MethodMethod to fractionatefractionate fractionatefractionate fractionatefractionate complexcomplex complex protein/protein/ protein/ protein/ peptide peptide peptidemixturesmixtures mixtures
• MS to acquire acquire the data data necessary necessary to identify identify identifyidentifyindividual individual individual individualproteins proteins
• Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformaticsto analyze analyze and assemble assemble the MS data
Homology modeling is a technique used to predict the 3D structure of a protein from its amino acid sequence by comparing it to proteins with similar sequences whose structures are already known. It involves searching a database for template structures, aligning the target sequence to the template, building a model by transferring 3D coordinates from the template to the target sequence, and validating the resulting model. Homology modeling works best when the sequence identity between the target and template is over 30% since protein structure is more conserved than sequence over evolution.
This document provides an outline of a lecture on the ICAT technique for quantitative proteomics. It begins with definitions of ICAT labeling and terminology used. ICAT labels peptides or proteins at cysteine residues with either light or heavy isotopic tags. The light tag contains hydrogen while the heavy tag contains deuterium. Tagged peptides are then purified using streptavidin affinity chromatography. The document discusses the need for gel-free proteomics due to limitations of gel-based methods. It provides an overview of the ICAT working protocol, which involves labeling proteins or peptides with light and heavy tags, trypsin digestion, affinity purification, and MS analysis to determine expression ratios.
Mapping and quantifying transcripts:
Northern blots
S1 mapping of 5’ and 3’ end transcripts
Primer extension
Runoff transcription and G –less cassette transcription
Nuclear Runon transcription
The document provides an overview of the Human Genome Project (HGP). It describes the HGP's goal of mapping and sequencing the entire human genome. The HGP was an international research effort that worked alongside a private company, Celera Genomics, to complete a rough draft of the human genome by 2000. The completion of the HGP marked a major scientific achievement and has transformed fields like medicine, biotechnology, and genetics by providing a comprehensive map of the human genetic code.
Energy minimization methods - Molecular ModelingChandni Pathak
Methods to minimize the energy of molecules during drug designing - Computational chemistry. According to the PCI syllabus, B.Pharm 8th Sem - Computer-Aided Drug Design (CADD).
This document asks a series of questions to help the reader reflect on their background, values, goals, strengths, communities, past achievements, and desired legacy. It prompts the reader to consider where they come from, what gives them strength, their hopes and dreams, what holds them back, who supports them, what past actions they are proud of, and what kind of legacy they want to leave. The questions are meant to guide self-reflection.
This document provides information about Passover and Ramadan. For Passover, it summarizes the biblical story of Moses being placed in a basket in the Nile river and rescued by Pharaoh's daughter before going on to lead the Israelites out of slavery in Egypt. For Ramadan, it summarizes the story of Muhammad receiving his first revelation from the angel Gabriel during the month of Ramadan in the year 610 CE. It then lists some common practices during Passover like having a seder meal and during Ramadan like fasting and giving charity. It concludes by asking questions about personal and family experiences with the holidays.
This agenda outlines the plans for a meeting that includes catching up with members, completing a crossword puzzle together, discussing an article, sharing thoughts on social media discourse, and setting goals for the chapter in 2021. The meeting will also touch on outreach plans for an early March event for 2nd to 5th graders and provide contact information for an optional planning meeting on January 24th.
This document contains the agenda and notes for a meeting of the Sisterhood of Salaam Shalom. The agenda includes an icebreaker where participants share a story from their life, breaking into small groups to discuss the stories, a conversation about voting and social issues, and making personal campaign posters. Announcements provide information about an upcoming conference and workshop, including registration details, as well as a media release form for a shared Google drive.
This document outlines the agenda for a meeting of the Sisterhood of Salaam Shalom Scottsdale/Phoenix Chapter. The meeting will include an icebreaker game of pictionary, a discussion of media representations of Muslims and Jews led by viewing video clips, an anonymous question and answer session about aspects of both faiths, and planning for their next meeting. It provides details on how to play pictionary and prompts for discussing the media clips. The document encourages participation in an anonymous question submission form and reminds members to sign a media form. It concludes by asking for any additional comments before ending the meeting.
This document outlines the agenda for a meeting of the Scottsdale/Phoenix chapter, including an icebreaker activity where members provide interesting facts about themselves without revealing their identity, a Kahoot trivia game, a discussion, and sharing of goals and interests. It introduces 12 members and their interesting facts, and discusses the objectives of developing understanding of individuals' religions and breaking down stereotypes by sharing meaningful religious objects. It concludes by requesting members sign a media release form.
This document summarizes the agenda for a meeting of the Sisterhood of Salaam Shalom Scottsdale/Phoenix Chapter. The agenda includes quick introductions of new members, an icebreaker activity to find commonalities in small groups, a discussion about members' names including their meanings and origins, a calligraphy lesson, reminders about signing a media release form, and plans to take a group picture at the next meeting.
The document summarizes the first meeting of a local chapter of the Sisterhood of Salaam Shalom. It includes introductions of the co-leaders and members, an overview of the purpose and basic rules of the chapter, announcements about upcoming events, and a question and answer game for the initial meeting. Members provided their contact information at the end to coordinate the next meeting.
This document introduces the concept of self-assembly as a bottom-up fabrication process by which living things assemble themselves from smaller components, unlike top-down fabrication where a constructor shapes a final product that is smaller than the starting material. It provides the example of cells assembling into a human to illustrate self-assembly, and suggests molecular self-assembly can be analogous to LEGO bricks spontaneously forming elaborate structures on their own.
DNA can be used as a programmable engineering molecule. While utilizing biological materials for unnatural purposes may seem strange, this is common such as using wood for construction or silk for clothing. The document discusses how DNA can be manipulated like molecular legos to be used for engineering applications in a similar way that other natural materials like wood and silk are already used for purposes beyond their natural functions.
Unlocking Productivity: Leveraging the Potential of Copilot in Microsoft 365, a presentation by Christoforos Vlachos, Senior Solutions Manager – Modern Workplace, Uni Systems
Essentials of Automations: The Art of Triggers and Actions in FMESafe Software
In this second installment of our Essentials of Automations webinar series, we’ll explore the landscape of triggers and actions, guiding you through the nuances of authoring and adapting workspaces for seamless automations. Gain an understanding of the full spectrum of triggers and actions available in FME, empowering you to enhance your workspaces for efficient automation.
We’ll kick things off by showcasing the most commonly used event-based triggers, introducing you to various automation workflows like manual triggers, schedules, directory watchers, and more. Plus, see how these elements play out in real scenarios.
Whether you’re tweaking your current setup or building from the ground up, this session will arm you with the tools and insights needed to transform your FME usage into a powerhouse of productivity. Join us to discover effective strategies that simplify complex processes, enhancing your productivity and transforming your data management practices with FME. Let’s turn complexity into clarity and make your workspaces work wonders!
zkStudyClub - Reef: Fast Succinct Non-Interactive Zero-Knowledge Regex ProofsAlex Pruden
This paper presents Reef, a system for generating publicly verifiable succinct non-interactive zero-knowledge proofs that a committed document matches or does not match a regular expression. We describe applications such as proving the strength of passwords, the provenance of email despite redactions, the validity of oblivious DNS queries, and the existence of mutations in DNA. Reef supports the Perl Compatible Regular Expression syntax, including wildcards, alternation, ranges, capture groups, Kleene star, negations, and lookarounds. Reef introduces a new type of automata, Skipping Alternating Finite Automata (SAFA), that skips irrelevant parts of a document when producing proofs without undermining soundness, and instantiates SAFA with a lookup argument. Our experimental evaluation confirms that Reef can generate proofs for documents with 32M characters; the proofs are small and cheap to verify (under a second).
Paper: https://eprint.iacr.org/2023/1886
Pushing the limits of ePRTC: 100ns holdover for 100 daysAdtran
At WSTS 2024, Alon Stern explored the topic of parametric holdover and explained how recent research findings can be implemented in real-world PNT networks to achieve 100 nanoseconds of accuracy for up to 100 days.
In the rapidly evolving landscape of technologies, XML continues to play a vital role in structuring, storing, and transporting data across diverse systems. The recent advancements in artificial intelligence (AI) present new methodologies for enhancing XML development workflows, introducing efficiency, automation, and intelligent capabilities. This presentation will outline the scope and perspective of utilizing AI in XML development. The potential benefits and the possible pitfalls will be highlighted, providing a balanced view of the subject.
We will explore the capabilities of AI in understanding XML markup languages and autonomously creating structured XML content. Additionally, we will examine the capacity of AI to enrich plain text with appropriate XML markup. Practical examples and methodological guidelines will be provided to elucidate how AI can be effectively prompted to interpret and generate accurate XML markup.
Further emphasis will be placed on the role of AI in developing XSLT, or schemas such as XSD and Schematron. We will address the techniques and strategies adopted to create prompts for generating code, explaining code, or refactoring the code, and the results achieved.
The discussion will extend to how AI can be used to transform XML content. In particular, the focus will be on the use of AI XPath extension functions in XSLT, Schematron, Schematron Quick Fixes, or for XML content refactoring.
The presentation aims to deliver a comprehensive overview of AI usage in XML development, providing attendees with the necessary knowledge to make informed decisions. Whether you’re at the early stages of adopting AI or considering integrating it in advanced XML development, this presentation will cover all levels of expertise.
By highlighting the potential advantages and challenges of integrating AI with XML development tools and languages, the presentation seeks to inspire thoughtful conversation around the future of XML development. We’ll not only delve into the technical aspects of AI-powered XML development but also discuss practical implications and possible future directions.
UiPath Test Automation using UiPath Test Suite series, part 6DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 6. In this session, we will cover Test Automation with generative AI and Open AI.
UiPath Test Automation with generative AI and Open AI webinar offers an in-depth exploration of leveraging cutting-edge technologies for test automation within the UiPath platform. Attendees will delve into the integration of generative AI, a test automation solution, with Open AI advanced natural language processing capabilities.
Throughout the session, participants will discover how this synergy empowers testers to automate repetitive tasks, enhance testing accuracy, and expedite the software testing life cycle. Topics covered include the seamless integration process, practical use cases, and the benefits of harnessing AI-driven automation for UiPath testing initiatives. By attending this webinar, testers, and automation professionals can gain valuable insights into harnessing the power of AI to optimize their test automation workflows within the UiPath ecosystem, ultimately driving efficiency and quality in software development processes.
What will you get from this session?
1. Insights into integrating generative AI.
2. Understanding how this integration enhances test automation within the UiPath platform
3. Practical demonstrations
4. Exploration of real-world use cases illustrating the benefits of AI-driven test automation for UiPath
Topics covered:
What is generative AI
Test Automation with generative AI and Open AI.
UiPath integration with generative AI
Speaker:
Deepak Rai, Automation Practice Lead, Boundaryless Group and UiPath MVP
UiPath Test Automation using UiPath Test Suite series, part 5DianaGray10
Welcome to UiPath Test Automation using UiPath Test Suite series part 5. In this session, we will cover CI/CD with devops.
Topics covered:
CI/CD with in UiPath
End-to-end overview of CI/CD pipeline with Azure devops
Speaker:
Lyndsey Byblow, Test Suite Sales Engineer @ UiPath, Inc.
“An Outlook of the Ongoing and Future Relationship between Blockchain Technologies and Process-aware Information Systems.” Invited talk at the joint workshop on Blockchain for Information Systems (BC4IS) and Blockchain for Trusted Data Sharing (B4TDS), co-located with with the 36th International Conference on Advanced Information Systems Engineering (CAiSE), 3 June 2024, Limassol, Cyprus.
A tale of scale & speed: How the US Navy is enabling software delivery from l...sonjaschweigert1
Rapid and secure feature delivery is a goal across every application team and every branch of the DoD. The Navy’s DevSecOps platform, Party Barge, has achieved:
- Reduction in onboarding time from 5 weeks to 1 day
- Improved developer experience and productivity through actionable findings and reduction of false positives
- Maintenance of superior security standards and inherent policy enforcement with Authorization to Operate (ATO)
Development teams can ship efficiently and ensure applications are cyber ready for Navy Authorizing Officials (AOs). In this webinar, Sigma Defense and Anchore will give attendees a look behind the scenes and demo secure pipeline automation and security artifacts that speed up application ATO and time to production.
We will cover:
- How to remove silos in DevSecOps
- How to build efficient development pipeline roles and component templates
- How to deliver security artifacts that matter for ATO’s (SBOMs, vulnerability reports, and policy evidence)
- How to streamline operations with automated policy checks on container images
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Climate Impact of Software Testing at Nordic Testing DaysKari Kakkonen
My slides at Nordic Testing Days 6.6.2024
Climate impact / sustainability of software testing discussed on the talk. ICT and testing must carry their part of global responsibility to help with the climat warming. We can minimize the carbon footprint but we can also have a carbon handprint, a positive impact on the climate. Quality characteristics can be added with sustainability, and then measured continuously. Test environments can be used less, and in smaller scale and on demand. Test techniques can be used in optimizing or minimizing number of tests. Test automation can be used to speed up testing.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
Unlock the Future of Search with MongoDB Atlas_ Vector Search Unleashed.pdfMalak Abu Hammad
Discover how MongoDB Atlas and vector search technology can revolutionize your application's search capabilities. This comprehensive presentation covers:
* What is Vector Search?
* Importance and benefits of vector search
* Practical use cases across various industries
* Step-by-step implementation guide
* Live demos with code snippets
* Enhancing LLM capabilities with vector search
* Best practices and optimization strategies
Perfect for developers, AI enthusiasts, and tech leaders. Learn how to leverage MongoDB Atlas to deliver highly relevant, context-aware search results, transforming your data retrieval process. Stay ahead in tech innovation and maximize the potential of your applications.
#MongoDB #VectorSearch #AI #SemanticSearch #TechInnovation #DataScience #LLM #MachineLearning #SearchTechnology
Goodbye Windows 11: Make Way for Nitrux Linux 3.5.0!SOFTTECHHUB
As the digital landscape continually evolves, operating systems play a critical role in shaping user experiences and productivity. The launch of Nitrux Linux 3.5.0 marks a significant milestone, offering a robust alternative to traditional systems such as Windows 11. This article delves into the essence of Nitrux Linux 3.5.0, exploring its unique features, advantages, and how it stands as a compelling choice for both casual users and tech enthusiasts.
DevOps and Testing slides at DASA ConnectKari Kakkonen
My and Rik Marselis slides at 30.5.2024 DASA Connect conference. We discuss about what is testing, then what is agile testing and finally what is Testing in DevOps. Finally we had lovely workshop with the participants trying to find out different ways to think about quality and testing in different parts of the DevOps infinity loop.
Dr. Sean Tan, Head of Data Science, Changi Airport Group
Discover how Changi Airport Group (CAG) leverages graph technologies and generative AI to revolutionize their search capabilities. This session delves into the unique search needs of CAG’s diverse passengers and customers, showcasing how graph data structures enhance the accuracy and relevance of AI-generated search results, mitigating the risk of “hallucinations” and improving the overall customer journey.