The report analyzes progress on 50 health-related SDG targets and indicators in the Eastern Mediterranean Region between 2015 and 2019. It finds that over half of the indicators showed some progress, including reductions in child malnutrition and increases in vaccination rates and healthcare workers. However, targets for reducing maternal, child, and neonatal mortality are still not being met. It also identifies five key challenges: weak governance, fragmented healthcare systems, limited data availability, emergencies like COVID-19, and issues of gender equality and health disparities. The way forward involves strengthening leadership, investing in health systems, expanding access to care, collaborating across sectors, and ensuring equity.