This document summarizes resolutions and decisions from various World Health Assembly and Executive Board meetings that are of regional concern. Key topics discussed include strategies for HIV, viral hepatitis, STIs, food safety, epilepsy, non-communicable diseases, harmful use of alcohol, social determinants of health, and sustainable financing. The regional office will support member states in implementing frameworks, strategies, and plans on these issues through regional consultations, capacity building, and technical guidance. Progress on non-communicable diseases and neurological disorders in particular falls short of targets in most member states in the region.