3. • Sever limb
unanesthetically
• Dip open stump in
boiling oil
• High mortality
rate
• Resulting stump is
poorly suited
Oil on board by an unknown artist, mid nineteenth century amputation
4. HISTORY
• Ligature: Hippocrates first use => lost during
the Dark Ages => Ambroise Paré in 1529
• Ambroise Paré: artery forceps
• 1674: Morel - tourniquet
• 1867: Lister - antiseptic technique
• The late 19th century: chloroform and
ether for general anesthesia
• => for the first time could fashion sturdy and
functional stumps.
5. HISTORY
• Surgeons completely understand
• surgical principles
• postoperative rehabilitation
• prosthetic design
• Improved prosthetic design does not compensate for a poorly
performed surgical procedure.
• Amputation not a failure of treatment but the first step
toward a more comfortable and productive life.
• Planned and performed with the same care and skill as
other reconstructive procedure
6. INCIDENCE
• 300.000 amputations the United States.
• The number is increasing - an aging population.
• > 90% secondary to peripheral vascular disease.
• In younger patients: trauma > malignancy
7. INDICATIONS
• The only absolute indication irreversible
ischemia
• in a diseased limb
• or traumatized limb
• To preserve life in uncontrollable
infections
• Best option in some tumors
• Limb is not as functional as a
prosthesis, certain congenital anomalies
of the lower extremity
TRAUMA
PERIPHE
RAL
VASCULA
R
DISEASE
BURNS
FROSTBI
TE
INFECTIO
N
TUMORS
8.
9.
10. PERIPHERAL VASCULAR DISEASE
• Extracranial carotid and vertebral artery disease
• Renal Arterial Disease
• Mesenteric Arterial Disease
• Lower Extremity Arterial Disease
• Aneurysms of the Abdominal Aorta, Its Branch Vessels
11. Lower Extremity Arterial Disease
• LEAD has several different
presentations, categorized
according to the Fontaine or
Rutherford classifications -
• Critical Limb Ischemia
12. Critical Limb Ischemia
• Critical limb ischaemia
is the most severe
clinical manifestation
of LEAD, defined
• presence of ischaemic
rest pain,
• ischaemic lesions or
gangrene objectively
attributable to arterial
occlusive disease.
14. Critical Limb Ischemia
Indication of amputation
ACCF/AHA ESC
Patients unsuitable for revascularization
• Class I Level of Evidence: C
15. Critical Limb Ischemia
Indication of amputation
Neurologically impaired or non-ambulatory
16. Acute limb ischemia
• Acute limb ischemia is defined
as a rapid or sudden decrease in
limb perfusion that threatens
limb viability.
• The five “Ps” suggest limb
jeopardy: pain, paralysis,
paresthesias, pulselessness, and
pallor.
• The level of emergency and the
choice of therapeutic strategy
depend on the clinical
presentation, mainly the
presence of neurological
deficiencies
17.
18. PERIPHERAL VASCULAR DISEASE
• Keep in mind: vascular disease has progressed to the
point of requiring amputation, not limited to the
involved extremity.
• Before performing an amputation for PAD, a vascular
surgery consultation is almost always indicated
• If amputation necessary, optimize surgical conditions:
albumin < 3.5 g/dL or lymphocyte <1500 cells/mL =>
complication
19. TRAUMA
• Whether the limb should
undergo salvage or
amputation?
• 8 studies
• Level III, Class IIb
• Gustilo IIIA fractures are unlikely to
require amputation
• Gustilo IIIB and IIIC fractures may require
amputation
20. • To remove subjectivity from the decision, available
scoring systems
• Mangled extremity severity score - most useful:
• easy to apply,
• grades the injury: the energy that caused the injury, limb isch-emia,
shock, and the patient’s age,
• ≤ 6 consistent with a salvageable limb, ≥ 7 amputation was the
eventual result
21.
22. • No scoring system can replace experience and good clinical
judgment
23. • Might be necessary to preserve
life
• Salvage a severely injured limb
may lead to metabolic overload
and secondary organ failure
(multiple injuries the elderly)
• Injury severity score > 50:
contraindication limb salvage
25. The tradeoffs - limb salvage
• Great cost.
• Multiple operations to obtain bony union , soft tissue
coverage, other areas to obtain donor tissue.
• External fixation may be necessary for several years
• Complications: infection, nonunion, or loss of a muscle flap.
• Chronic pain and drug addiction
• Isolation from family and friends, unemployment.
• The limb ultimately could require amputation,
26. The tradeoffs - early amputation
• Decreased morbidity, fewer operations, shorter hospital course,
decreased hospital costs, shorter rehabilitation, earlier return
to work.
• Modern prosthetics better function than many “successfully”
salvaged limbs.
• In long term studies, patients who have undergone amputation
and prosthetic fitting are more likely to remain working and are
far less likely to consider themselves to be “severely disabled”
than patients who have endured an extensive limb
27. DETERMINATION OF AMPUTATION LEVEL
• Tradeoffs
• more distal level of amputation → more function
• more proximal level of amputation → less complication
• Patient’s general medical condition
• A vascular surgery consultation: “Even if revascularization would
not allow for salvage of the entire limb, it may allow for healing
of a partial foot or ankle amputation instead of a transtibial
amputation”
• Simple screening tests
28. • Waters et al. studied
the energy cost of
walking for patients
with amputations
velocity
energy
100%
66%
59%
44%
87%
63%
normal Syme transtibial transfemoral transtibial
(trauma)
transfemoral
(trauma)
29. • If ambulation is the chief concern, amputation should be
performed at the most distal level possible
• If a patient has no ambulatory potential, wound healing
with decreased perioperative morbidity should be
the chief concern
30. DETERMINATION OF AMPUTATION LEVEL
• Determining the most distal level for
amputation with a reasonable chance
of healing can be challenging
• Transcutaneous oxygen measurements
• Different cutoff levels, ranging from 20
to 40 mm Hg, for “good” healing
potential
31. TECHNICAL ASPECTS
• SKIN AND MUSCLE FLAPS
• Flaps should be kept thick
• The scar should not be adherent to the underlying bone
• Muscles usually are divided at least 5 cm distal to
the intended bone resection and may be stabilized by
myodesis or myoplasty
32. TECHNICAL ASPECTS
• HEMOSTASIS
• Tourniquet
• Major blood vessels isolated and ligated
• A drain should be used in most cases for 48 to 72
hours
33. TECHNICAL ASPECTS
• NERVES
• A neuroma always forms
• Becomes painful if it forms in a position subjected to
repeated trauma.
• Nerves: gently pulled distally into the wound, divided
cleanly with a sharp knife so that the cut end retracts
proximal to the level of bone resection.
34. TECHNICAL ASPECTS
• BONE
• Excessive periosteal stripping is contraindicated.
• Bony prominences that would not be well padded
by soft tissue always should be resected
• The remaining rasped to form a smooth contour:
especially important the anterior aspect of the tibia,
lateral aspect of the femur, and radial styloid
35. TECHNICAL ASPECTS
• OPEN AMPUTATIONS
• infections severe traumatic wounds with extensive
destruction of tissue and gross contamination by
foreign material.
• open amputations with inverted skin flaps and
circular open amputations with postoperative skin trac-tion
• technique of vacuumassisted closure
36. POSTOPERATIVE CARE
• Requires a multidisciplinary team
approach
• Since the mid 1970s, there has been a
gradual shift from the use of
“conventional” soft dressings to the use
of rigid dressings
37.
38. Rigid dressings - advantages
• prevent edema at the surgical site
• protect the wound from bed trauma
• enhance wound healing and early maturation of the stump
• decrease postoperative pain, allowing earlier mobilization
• transtibial amputations: prevent flexion contractures
39. POSTOPERATIVE CARE
• Position the stump properly
• Exercises for the stump
• Remove rigid dressing in 7 to 10 day
• Cast change weekly until the wound heal
• Continue until the volume appears unchanged from the previous
week
• At that time, the prosthetist may apply the first prosthesis.
Early
surgical amputation was a crude procedure by which a limb
was rapidly severed from an unanesthetized patient. The open
stump was crushed or dipped in boiling oil to obtain hemo
stasis. The procedure was associated with a high mortality
rate. For patients who survived, the resulting stump was
poorly suited for prosthetic fitting.
Hippocrates was the first to use ligatures; this technique
was lost during the Dark Ages but was reintroduced in 1529
by Ambroise Paré, a French military surgeon. Paré also intro
duced the “artery forceps.” He was able to reduce the mortal
ity rate significantly while creating a more functional stump.
He also designed relatively sophisticated prostheses. Further
advances were made possible by Morel’s introduction of the
tourniquet in 1674 and Lister’s introduction of antiseptic
technique in 1867. With the use of chloroform and ether
for general anesthesia in the late 19th century, surgeons
for the first time could fashion reasonably sturdy and func
tional stumps.
Now more than ever it is important that amputations be performed by surgeons who have a complete understanding of amputation surgical principles, postoperative rehabilitation, and prosthetic design.
Improved prosthetic design does not compensate for a poorly performed surgical procedure.
Amputation should not be viewed as a failure of treatment but rather as the first step toward a patient’s return to a more comfortable and productive life.
The operative procedure should be planned and performed with the same care and skill used in any other reconstructive procedure
The National Center for Health Statistics estimated that more
than 300,000 patients with amputations live in the United
States. The number of amputations performed each year is
increasing, mainly because of an aging population. More than
90% of amputations performed in the Western world are
secondary to peripheral vascular disease. In younger patients,
trauma is the leading cause, followed by malignancy.
The National Center for Health Statistics estimated that more
than 300,000 patients with amputations live in the United
States. The number of amputations performed each year is
increasing, mainly because of an aging population. More than
90% of amputations performed in the Western world are
secondary to peripheral vascular disease. In younger patients,
trauma is the leading cause, followed by malignancy.
The most typical presentation of LEAD is intermittent claudication,
characterized by pain in the calves, increasing with walking; the pain
typically disappears quickly at rest (Fontaine stage II; Rutherford
grade I).
Critical limb ischaemia is the most severe clinical manifestation
of LEAD, defined as the presence of ischaemic rest pain, and ischaemic lesions or gangrene objectively attributable to arterial
occlusive disease.
The most typical presentation of LEAD is intermittent claudication,
characterized by pain in the calves, increasing with walking; the pain
typically disappears quickly at rest (Fontaine stage II; Rutherford
grade I).
Critical limb ischaemia is the most severe clinical manifestation
of LEAD, defined as the presence of ischaemic rest pain, and ischaemic lesions or gangrene objectively attributable to arterial
occlusive disease.
The most typical presentation of LEAD is intermittent claudication,
characterized by pain in the calves, increasing with walking; the pain
typically disappears quickly at rest (Fontaine stage II; Rutherford
grade I).
Critical limb ischaemia is the most severe clinical manifestation
of LEAD, defined as the presence of ischaemic rest pain, and ischaemic lesions or gangrene objectively attributable to arterial
occlusive disease.
The most typical presentation of LEAD is intermittent claudication,
characterized by pain in the calves, increasing with walking; the pain
typically disappears quickly at rest (Fontaine stage II; Rutherford
grade I).
Critical limb ischaemia is the most severe clinical manifestation
of LEAD, defined as the presence of ischaemic rest pain, and ischaemic lesions or gangrene objectively attributable to arterial
occlusive disease.
Most patients also have concomitant disease processes in the cerebral vasculature, coronary arteries, and kidneys. In addition to obtaining a vascular surgery consultation to evaluate the diseased limb, appropriate consultation is indicated to evaluate these other systems
Most patients also have concomitant disease processes in the cerebral vasculature, coronary arteries, and kidneys. In addition to obtaining a vascular surgery consultation to evaluate the diseased limb, appropriate consultation is indicated to evaluate these other systems
Other authors have attempted to remove subjectivity from the decisionmaking process
On entering the hospi
tal, most patients are concerned only with saving the limb;
they must be made to understand that this often comes at a
great cost. They may have to face multiple operations to
obtain bony union and soft tissue coverage and multiple
operations on other areas to obtain donor tissue. External
fixation may be necessary for several years, and complica
tions, including infection, nonunion, or loss of a muscle flap,
may occur. Chronic pain and drug addiction also are common
problems of limb salvage because patients endure multiple
hospital admissions and surgery, isolation from their family
and friends, and unemployment. In the end, despite heroic
efforts, the limb ultimately could require amputation, or
a “successfully” salvaged limb may be chronically painful
or functionless
A transtibial amputation in this setting is not a
reasonable option because of the increased risk of wound
problems and increased skin problems from knee flexion
contractures. A knee disarticulation often provides the best
function for these patients. Compared with transfemoral
amputation, knee disarticulation provides a longer lever arm
with balanced musculature to help with bed mobility and
transfers. In addition, muscles are not divided and do not
atrophy and contract over the femur as they often do after
transfemoral amputation. Finally, better sitting stability and
comfort are provided with a throughknee amputation