A powerpoint on the Human Excretory System, intended for the SA Grade 11 Life Sciences Syllabus. Includes information on kidneys, osmoregulation, nephrons, excretion, etc. Hope it helps :)
A powerpoint on the Human Excretory System, intended for the SA Grade 11 Life Sciences Syllabus. Includes information on kidneys, osmoregulation, nephrons, excretion, etc. Hope it helps :)
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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1. URINARY SYSTEM
The urinary system includes the kidneys, bladder and tubes. These organs
control the amount of water and salts that are absorbed back into the blood
and what is taken out as waste. This system also acts as a filtering
mechanism for the blood.
The urinary tract is a pathway that includes the:
Kidneys: two bean-shaped organs that filter waste from the blood and
produce urine
Ureters: two thin tubes that take urine from the kidney to the bladder
Bladder: a sac that holds pee until it's time to go to the bathroom
Urethra: the tube that carries urine from the bladder out of the body when
you urinate
The kidneys are key players in the urinary tract. They do two important jobs
which is filter waste from the blood and produce urine to get rid of it. If they
don’t do this, toxins which is bad stuff would quickly build up in your body
and make you sick.
That's why you hear about people getting kidney transplants sometimes.
You need at least one working kidney to be healthy.
You might wonder how your body ends up with waste it needs to get rid of.
Body processes such as digestion and metabolism that is when the body
turns food into energy produce wastes, or byproducts. The body takes what it
needs, but the waste has to go somewhere. Thanks to the kidneys and urine,
it has a way to get out.
When you're asked to give a urine sample during a doctor's visit, the results
reveal how well your two kidneys are working. For example, white blood
cells in the urine can be a sign of an infection.
Urine also is a way for your body to keep the right amount of water. Did you
ever notice that if you drink a lot, you urinate more and the urine is pale
yellow? That's because your body is getting rid of extra water and your urine
2. has more water in it than usual.
Six important roles of the kidneys are
Regulation of plasma ionic composition. Ions such as sodium, potassium,
calcium, magnesium, chloride, bicarbonate, and phosphates are regulated by
the amount that the kidney excretes.
Regulation of plasma osmolarity. The kidneys regulate osmolarity because
they have direct control over how many ions and how much water a person
excretes.
Regulation of plasma volume. Your kidneys are so important they even
have an effect on your blood pressure. The kidneys control plasma volume
by controlling how much water a person excretes. The plasma volume has a
direct effect on the total blood volume, which has a direct effect on your
blood pressure. Salt(NaCl)will cause osmosis to happen; the diffusion of
water into the blood.
Regulation of plasma hydrogen ion concentration (pH). The kidneys
partner up with the lungs and they together control the pH. The kidneys have
a major role because they control the amount of bicarbonate excreted or held
onto. The kidneys help maintain the blood Ph mainly by excreting hydrogen
ions and reabsorbing bicarbonate ions as needed.
Removal of metabolic waste products and foreign substances from the
plasma. One of the most important things the kidneys excrete is nitrogenous
waste. As the liver breaks down amino acids it also releases ammonia. The
liver then quickly combines that ammonia with carbon dioxide, creating urea
which is the primary nitrogenous end product of metabolism in humans. The
liver turns the ammonia into urea because it is much less toxic. We can also
excrete some ammonia, creatinine and uric acid. The creatinine comes from
the metabolic breakdown of creatine phospate (a high-energy phosphate in
muscles). Uric acid comes from the break down of nucleotides. Uric acid is
insoluble and too much uric acid in the blood will build up and form crystals
that can collect in the joints and cause gout.
Secretion of Hormones The endocrine system has assistance from the
kidney's when releasing hormones. Renin is released by the kidneys. Renin
leads to the secretion of aldosterone which is released from the adrenal
3. cortex. Aldosterone promotes the kidneys to reabsorb the sodium (Na+) ions.
The kidneys also secrete erythropoietin when the blood doesn't have the
capacity to carry oxygen. Erythropoietin stimulates red blood cell
production. The Vitamin D from the skin is also activated with help from the
kidneys. Calcium (Ca+) absorption from the digestive tract is promoted by
vitamin D.