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ANTENATAL CARE
Ephrem Yohannes (MSc in
Maternity and Neonatology)
12/2/2019 1
Outline
 Historical back ground
 Organization of prenatal care
 Describe the objectives of antenatal care
 Discuss different models of antenatal care
 Describe activities of antenatal care
 Outline ANC fetal well being assessment
strategies
 Discuss health interventions during ANC
12/2/2019 2
Historical back ground
 in US was introduced by social reformers and
nurses
 An outpatient prenatal clinic was established
in 1911
 In 1954, Nicholas J. Eastman "done more to
save mothers' lives in our time than any other
single factor"
12/2/2019 3
…Con
The antenatal period presents opportunities
– Inform about danger signs and symptoms
– The risks of labor and delivery
– Delivery with skilled healthcare provider
– Information on birth spacing
– Intervention-
• Tetanus immunization
• Prevention and Rx of malaria, anemia, STI
• HIV prevention and care
12/2/2019 4
Organization of Prenatal Care
 Essence of ANC as described by ACOG
The contents include;
1.Preconceptional care
2.Prompt diagnosis of pregnancy
3.Initial prenatal evaluation
4.Follow-up prenatal visits
12/2/2019 5
Aim of ANC
• The goal of antenatal care is to
have a healthy mother and baby
by monitoring their well
beingness during pregnancy
12/2/2019 6
Objectives
 Timely detection and management of cpx
 Ensure the birth of a healthy child
 Ensure the health of the mother
 Provide essential health education to the mother
12/2/2019 7
Models
• Two models of prenatal care provision
1.Traditional ANC model /Routine
2.Focused ANC
3.New WHO recommendation
12/2/2019 8
Routine ANC
• Begin almost two hundred years ago.
• Based on European models developed in the
early 1900s.
• that were traditionally thought to benefit the
mother and her fetus.
12/2/2019 9
Routine ANC
Components of Traditional ANC model
• Frequent visits
• Routine screening
• Monitoring of Ht, Wt, ankle edema
• Risk approach
12/2/2019 10
Routine ANC
 Visit pattern
Every 4 weeks till 28 weeks
Every 2 weeks from 28-36 weeks
Every week from 36 weeks till delivery
 Total number of visits 12-14
12/2/2019 11
WHO Recommendations
• Goal oriented and
• Focused on “screening to detect a problem
rather than screening to predict a problem”
and on treating any problem that can
complicate a pregnancy.
12/2/2019 12
WHO Recommendations
Final Recommendations
1. four focused visits as sufficient for normal
pregnancy (now 8)
• Goal-directed visits by skilled provider
12/2/2019 13
WHO Recommendations
2. Birth Preparedness
• Skilled attendant
• Place of delivery
• Finance
• Nutrition
• Essential items
12/2/2019 14
WHO Recommendations
3. Readiness for Complications
• Early detection
• Designated decision maker(s)
• Emergency funds
• Communication
• Transport
• Blood donors
12/2/2019 15
WHO Recommendations
4. Counseling
• Nutrition
• Family planning
• Breastfeeding
• Danger signs
• HIV/STIs
12/2/2019 16
WHO Recommendations
5. Detection and management of existing
diseases and conditions
• HIV – Voluntary counseling and testing
• STIs, including syphilis
• Tuberculosis
• Malaria
12/2/2019 17
WHO Recommendations
6. Detection and management of complications
• Severe anemia
• Vaginal bleeding
• Pre-eclampsia /eclampsia
• Malpresentation after 36 weeks
12/2/2019 18
WHO Recommendations
7. Prevention
• For all women
- Tetanus toxoid
- Iron and folate supplementation
• In select populations
- Malaria - intermittent preventive treatment
- Routine hookworm treatment
- Vitamin A supplementation
12/2/2019 19
2016 WHO ANC
model
• FANC model, which was developed in the
1990s, is probably associated with more
perinatal deaths than models that comprise at
least eight ANC visits.
• More ANC visits, irrespective of the resource
setting, is probably associated with greater
maternal satisfaction than less ANC visits.
12/2/2019 20
• Prefers the word “contact” to “visit”, as it
implies an active connection between a
pregnant woman and a health-care provider
that is not implicit with the word “visit”.
12/2/2019 21
• The decision regarding the number of contacts
was also influenced by:
– Safety
– health system communication and support
– No differences between 8 ANC and (11–15)
contacts
– Contact between px women and knowledgeable,
supportive and respectful health-care
practitioners
12/2/2019 22
12/2/2019 23
FOCUSED ANC
12/2/2019 24
Principles of focused ANC
1. Simple classifying form
2. Identification of high risk women and referral
3. Well coming all women at the clinic
4. Only necessary examinations and tests
performed
5. Rapid & easy test
6. Treatment should start the same day
12/2/2019 25
Focused ANC
• Intended only for pregnant women with out ----
- evidence of pregnancy-related complications,
- medical or major health-related risk factors.
• Two groups of px mother by using the
classifying form
- Basic model
- Comprehensive model
12/2/2019 26
WHO ANC Model
All women
first visit ANC
Classifying
form
Any condition or
risk factors detected
in applying
classifying form
NO
YES
Basic Component
of ANC
Program(25%)
Specialist care/
additional assessment
or follow-up if
needed in clinic or
elsewhere(75%)
Transfer of patients
between basic component
and specialized care is
possible throughout ANC
12/2/2019 27
CLASSIFYING FORM - Criteria
• OBSTETRIC HISTORY
1. Previous SB/ neonatal loss?
2. Recurrent abortions?
3. BWt of last baby < 2500g?
4. BWt of last baby > 4500g?
5. hospital admission for hdp?
6. Previous surgery on
reproductive tract?
• CURRENT
PREGNANCY
7. Diagnosed or suspected
multiple pregnancy?
8. Age less than 16 years?
9. Age more than 40 years?
10. Isoimmunization Rh (-)
11. Vaginal bleeding?
12. Pelvic mass?
13. DSP 90mm Hg or more at
booking?
GENERAL MEDICAL
14. Insulin-DM?
15. Renal disease?
16. Cardiac disease?
17. Known 'substance' abuse?
18. Any other severe medical
disease?
NB: yes to any one – Not
eligible
12/2/2019 28
Framework of Focused ANC
• Disease detection
• Counseling and health promotion
• Birth preparedness
• Complication readiness
12/2/2019 29
Basic component
Timing of visits
1st- up to 12 weeks
2nd- 24-28 weeks
3rd- at 32 weeks
4th- at 36 weeks
5th- 40-42 weeks- optional
12/2/2019 30
Contents of ANC visits
Disease detection / Screening
Care provision
Health promotion
• Each visit of ANC requires about 20-30
minutes.
12/2/2019 31
Initial visit
• Should occur in the 1st trimester at ≤12 weeks
or regardless of the GA at 1st enrolment.
• Irrespective of gestation at 1st visit, all
pregnant women should go through first visit
contents in addition…
• Expected to take 30– 40 minutes.
• Emphasis on medical/obstetric HX – eligibility
12/2/2019 32
Initial visit- History
Present pregnancy-
• Accurate dating of gestational age
• Any symptoms – minor or major complaints
• Fetal movement perception
• ANC details if mother is referred from other
• Presence of any of the danger signs
12/2/2019 33
Initial visit- History
Past obstetric history
• Details of any obstetric complication
Family history
• Any familial medical conditions
• DM, HDP, Congenital anomalies
Personal history
• History of medical illnesses
• Substance intaking
12/2/2019 34
Initial visit- Physical Exam
• Vital signs and anthropometry
• Abdominal examination
 Fundal height palpation in non obese women at 20
to 34 weeks gestation
 Fetal heart auscultation after 10th week by doppler
or 20th week by fetal heart stethoscope
 Fetal presentation after the 28th week but
malpresentations abnormal after the 36th week
12/2/2019 35
Initial visit- Physical Exam
• Pelvic examination
 For uterine size measurement if GA< 12th week
 Adnexal abnormalities or masses
 Early evidence of pregnancy on physical exam-
 cervical softening; Chadwick’s sign( bluish color of
vagina, cervix); Von-Fernwald’s sign( localized
softening of the fundus) and Hegar’s sign
12/2/2019 36
Assess for referral
• LMP and EDD
• Need for special care
– Diabetes
– Heart disease
– Renal disease
– HIV positive
– Severe anaemia, previous SB, Previous HDP, Previous
CS,
– High BP
12/2/2019 37
Implement interventions
• Iron & folate supplementation
• Treat STIs
• TT 1st injection
• IPT for Malaria
• PMTCT~ (asses for prophylaxis or HAART)
• Refer high-risk cases as above
12/2/2019 38
Advice, Q&A
• Safe sex
• Nutrition
• Whom to call for emergency
• Birth plan
• Invite partner
• Schedule next appointment
• Maintain complete records
12/2/2019 39
Subsequent visits – Activities
History
• Follow up on previous complaints
• Any new complaints since last visits
• Development of any of the danger
symptoms
• Fetal movements history
12/2/2019 40
Subsequent visits – Activities
Physical examination
• Brief detailed exam including the vital signs,
anthropometry and general examination
• Adequacy of weight gain since last visit
• Adequacy of fundal growth since last visit
• Presence of fetal heart beat
• Presence of other findings such as
generalized edema
12/2/2019 41
Diagnostic work-up during antenatal care
42
Diagnostic procedure Gestational age
Hemoglobin/hematocrit determination Initial visit; repeat at 28-32 weeks
ABO and RH typing Initial visit
VDRL Initial visit; repeat at 28 weeks if negative
Urinalysis At each visit to detect proteinuria
Urine culture and sensitivity Initial visit to detect asymptomatic
bacteriuria
Indirect Coomb’s test Initial visit
Serum alpha-fetoprotein test 16-18 weeks
Routine ultrasonography 16-18 weeks
Screening test for gestational diabetes 24-28 weeks
Pap smear Initial visit
Cervical smear gram stain and culture Initial visit
HBsAg; HIV tests Initial visit12/2/2019
Assurance of fetal well being at ANC- Strategies
43
Progressive increase in maternal weight
Progressive fundal height growth as per
expectations
Adequate maternal perception of fetal
movement (at least 10 in 12 hours)
Fetal well being tests – from 28 weeks onwards
• Non stress test
• Contraction stress test
• Fetal biophysical profile score
• Doppler ultrasound velocimetry
Ultrasonographic fetal scan for anomalies
12/2/2019
Record keeping
• At 4th visit give the client a copy of her
antenatal card to take to the unit of choice of
delivery.
12/2/2019 44
THANK YOU
12/2/2019 45

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Essential Guide to Antenatal Care

  • 1. ANTENATAL CARE Ephrem Yohannes (MSc in Maternity and Neonatology) 12/2/2019 1
  • 2. Outline  Historical back ground  Organization of prenatal care  Describe the objectives of antenatal care  Discuss different models of antenatal care  Describe activities of antenatal care  Outline ANC fetal well being assessment strategies  Discuss health interventions during ANC 12/2/2019 2
  • 3. Historical back ground  in US was introduced by social reformers and nurses  An outpatient prenatal clinic was established in 1911  In 1954, Nicholas J. Eastman "done more to save mothers' lives in our time than any other single factor" 12/2/2019 3
  • 4. …Con The antenatal period presents opportunities – Inform about danger signs and symptoms – The risks of labor and delivery – Delivery with skilled healthcare provider – Information on birth spacing – Intervention- • Tetanus immunization • Prevention and Rx of malaria, anemia, STI • HIV prevention and care 12/2/2019 4
  • 5. Organization of Prenatal Care  Essence of ANC as described by ACOG The contents include; 1.Preconceptional care 2.Prompt diagnosis of pregnancy 3.Initial prenatal evaluation 4.Follow-up prenatal visits 12/2/2019 5
  • 6. Aim of ANC • The goal of antenatal care is to have a healthy mother and baby by monitoring their well beingness during pregnancy 12/2/2019 6
  • 7. Objectives  Timely detection and management of cpx  Ensure the birth of a healthy child  Ensure the health of the mother  Provide essential health education to the mother 12/2/2019 7
  • 8. Models • Two models of prenatal care provision 1.Traditional ANC model /Routine 2.Focused ANC 3.New WHO recommendation 12/2/2019 8
  • 9. Routine ANC • Begin almost two hundred years ago. • Based on European models developed in the early 1900s. • that were traditionally thought to benefit the mother and her fetus. 12/2/2019 9
  • 10. Routine ANC Components of Traditional ANC model • Frequent visits • Routine screening • Monitoring of Ht, Wt, ankle edema • Risk approach 12/2/2019 10
  • 11. Routine ANC  Visit pattern Every 4 weeks till 28 weeks Every 2 weeks from 28-36 weeks Every week from 36 weeks till delivery  Total number of visits 12-14 12/2/2019 11
  • 12. WHO Recommendations • Goal oriented and • Focused on “screening to detect a problem rather than screening to predict a problem” and on treating any problem that can complicate a pregnancy. 12/2/2019 12
  • 13. WHO Recommendations Final Recommendations 1. four focused visits as sufficient for normal pregnancy (now 8) • Goal-directed visits by skilled provider 12/2/2019 13
  • 14. WHO Recommendations 2. Birth Preparedness • Skilled attendant • Place of delivery • Finance • Nutrition • Essential items 12/2/2019 14
  • 15. WHO Recommendations 3. Readiness for Complications • Early detection • Designated decision maker(s) • Emergency funds • Communication • Transport • Blood donors 12/2/2019 15
  • 16. WHO Recommendations 4. Counseling • Nutrition • Family planning • Breastfeeding • Danger signs • HIV/STIs 12/2/2019 16
  • 17. WHO Recommendations 5. Detection and management of existing diseases and conditions • HIV – Voluntary counseling and testing • STIs, including syphilis • Tuberculosis • Malaria 12/2/2019 17
  • 18. WHO Recommendations 6. Detection and management of complications • Severe anemia • Vaginal bleeding • Pre-eclampsia /eclampsia • Malpresentation after 36 weeks 12/2/2019 18
  • 19. WHO Recommendations 7. Prevention • For all women - Tetanus toxoid - Iron and folate supplementation • In select populations - Malaria - intermittent preventive treatment - Routine hookworm treatment - Vitamin A supplementation 12/2/2019 19
  • 20. 2016 WHO ANC model • FANC model, which was developed in the 1990s, is probably associated with more perinatal deaths than models that comprise at least eight ANC visits. • More ANC visits, irrespective of the resource setting, is probably associated with greater maternal satisfaction than less ANC visits. 12/2/2019 20
  • 21. • Prefers the word “contact” to “visit”, as it implies an active connection between a pregnant woman and a health-care provider that is not implicit with the word “visit”. 12/2/2019 21
  • 22. • The decision regarding the number of contacts was also influenced by: – Safety – health system communication and support – No differences between 8 ANC and (11–15) contacts – Contact between px women and knowledgeable, supportive and respectful health-care practitioners 12/2/2019 22
  • 25. Principles of focused ANC 1. Simple classifying form 2. Identification of high risk women and referral 3. Well coming all women at the clinic 4. Only necessary examinations and tests performed 5. Rapid & easy test 6. Treatment should start the same day 12/2/2019 25
  • 26. Focused ANC • Intended only for pregnant women with out ---- - evidence of pregnancy-related complications, - medical or major health-related risk factors. • Two groups of px mother by using the classifying form - Basic model - Comprehensive model 12/2/2019 26
  • 27. WHO ANC Model All women first visit ANC Classifying form Any condition or risk factors detected in applying classifying form NO YES Basic Component of ANC Program(25%) Specialist care/ additional assessment or follow-up if needed in clinic or elsewhere(75%) Transfer of patients between basic component and specialized care is possible throughout ANC 12/2/2019 27
  • 28. CLASSIFYING FORM - Criteria • OBSTETRIC HISTORY 1. Previous SB/ neonatal loss? 2. Recurrent abortions? 3. BWt of last baby < 2500g? 4. BWt of last baby > 4500g? 5. hospital admission for hdp? 6. Previous surgery on reproductive tract? • CURRENT PREGNANCY 7. Diagnosed or suspected multiple pregnancy? 8. Age less than 16 years? 9. Age more than 40 years? 10. Isoimmunization Rh (-) 11. Vaginal bleeding? 12. Pelvic mass? 13. DSP 90mm Hg or more at booking? GENERAL MEDICAL 14. Insulin-DM? 15. Renal disease? 16. Cardiac disease? 17. Known 'substance' abuse? 18. Any other severe medical disease? NB: yes to any one – Not eligible 12/2/2019 28
  • 29. Framework of Focused ANC • Disease detection • Counseling and health promotion • Birth preparedness • Complication readiness 12/2/2019 29
  • 30. Basic component Timing of visits 1st- up to 12 weeks 2nd- 24-28 weeks 3rd- at 32 weeks 4th- at 36 weeks 5th- 40-42 weeks- optional 12/2/2019 30
  • 31. Contents of ANC visits Disease detection / Screening Care provision Health promotion • Each visit of ANC requires about 20-30 minutes. 12/2/2019 31
  • 32. Initial visit • Should occur in the 1st trimester at ≤12 weeks or regardless of the GA at 1st enrolment. • Irrespective of gestation at 1st visit, all pregnant women should go through first visit contents in addition… • Expected to take 30– 40 minutes. • Emphasis on medical/obstetric HX – eligibility 12/2/2019 32
  • 33. Initial visit- History Present pregnancy- • Accurate dating of gestational age • Any symptoms – minor or major complaints • Fetal movement perception • ANC details if mother is referred from other • Presence of any of the danger signs 12/2/2019 33
  • 34. Initial visit- History Past obstetric history • Details of any obstetric complication Family history • Any familial medical conditions • DM, HDP, Congenital anomalies Personal history • History of medical illnesses • Substance intaking 12/2/2019 34
  • 35. Initial visit- Physical Exam • Vital signs and anthropometry • Abdominal examination  Fundal height palpation in non obese women at 20 to 34 weeks gestation  Fetal heart auscultation after 10th week by doppler or 20th week by fetal heart stethoscope  Fetal presentation after the 28th week but malpresentations abnormal after the 36th week 12/2/2019 35
  • 36. Initial visit- Physical Exam • Pelvic examination  For uterine size measurement if GA< 12th week  Adnexal abnormalities or masses  Early evidence of pregnancy on physical exam-  cervical softening; Chadwick’s sign( bluish color of vagina, cervix); Von-Fernwald’s sign( localized softening of the fundus) and Hegar’s sign 12/2/2019 36
  • 37. Assess for referral • LMP and EDD • Need for special care – Diabetes – Heart disease – Renal disease – HIV positive – Severe anaemia, previous SB, Previous HDP, Previous CS, – High BP 12/2/2019 37
  • 38. Implement interventions • Iron & folate supplementation • Treat STIs • TT 1st injection • IPT for Malaria • PMTCT~ (asses for prophylaxis or HAART) • Refer high-risk cases as above 12/2/2019 38
  • 39. Advice, Q&A • Safe sex • Nutrition • Whom to call for emergency • Birth plan • Invite partner • Schedule next appointment • Maintain complete records 12/2/2019 39
  • 40. Subsequent visits – Activities History • Follow up on previous complaints • Any new complaints since last visits • Development of any of the danger symptoms • Fetal movements history 12/2/2019 40
  • 41. Subsequent visits – Activities Physical examination • Brief detailed exam including the vital signs, anthropometry and general examination • Adequacy of weight gain since last visit • Adequacy of fundal growth since last visit • Presence of fetal heart beat • Presence of other findings such as generalized edema 12/2/2019 41
  • 42. Diagnostic work-up during antenatal care 42 Diagnostic procedure Gestational age Hemoglobin/hematocrit determination Initial visit; repeat at 28-32 weeks ABO and RH typing Initial visit VDRL Initial visit; repeat at 28 weeks if negative Urinalysis At each visit to detect proteinuria Urine culture and sensitivity Initial visit to detect asymptomatic bacteriuria Indirect Coomb’s test Initial visit Serum alpha-fetoprotein test 16-18 weeks Routine ultrasonography 16-18 weeks Screening test for gestational diabetes 24-28 weeks Pap smear Initial visit Cervical smear gram stain and culture Initial visit HBsAg; HIV tests Initial visit12/2/2019
  • 43. Assurance of fetal well being at ANC- Strategies 43 Progressive increase in maternal weight Progressive fundal height growth as per expectations Adequate maternal perception of fetal movement (at least 10 in 12 hours) Fetal well being tests – from 28 weeks onwards • Non stress test • Contraction stress test • Fetal biophysical profile score • Doppler ultrasound velocimetry Ultrasonographic fetal scan for anomalies 12/2/2019
  • 44. Record keeping • At 4th visit give the client a copy of her antenatal card to take to the unit of choice of delivery. 12/2/2019 44

Editor's Notes

  1. The 2nd half of the 20th century-developing countries inspired by the tragedy of maternal mortality Focused attention on ANC rather than delivery care
  2. Routine screening with U/A ( prtein, UTI ) Haemathology ( Hgburia, BG and RH, …) -Multiple visits with various interventions at each visit -Risk assessment was the major goal of antenatal care.
  3. Goal directed Address most prevalent health issues affecting women and newborns Adjusted for specific populations/regions Appropriate to gestational age Based on firm rationale
  4. 4 visits are sufficient and for pregnancies without complications additional visits to do not affect maternal or perinatal outcomes Emphasis is on quality, rather than quantity of visits. Skilled provider – A review in the Cochrane database of 3 randomized controlled trials of routine antenatal care provided by midwives compared with shared care led by obstetricians found all 3 similar in terms of clinical efficacy and perception of care (women’s satisfaction). Source: Villar J, D Khan-Neelofur. 2001. Patterns of routine antenatal care for low-risk pregnancy (Cochrane Review), in The Cochrane Library, Issue 1. Oxford: Update Software. Midwife-managed care, as opposed to obstetrical-led care, has similar, or in some instances, more favorable outcomes (also reduction in cost). The number of visits recommended by WHO for routine care (no complications) is four. Source: World Health Organization (WHO). 1996. Antenatal Care: Report of a Technical Working Group. WHO: Geneva, Switzerland. 1st visit – before 4 months (as early as possible in pregnancy) 2nd visit – 6 to 7 months 3rd visit – 8 months 4th visit – 9 months Follow-up visit
  5. Planning and preparation for mother, family, community and skilled care provider Individual birth plans will be shaped by the culture, socioeconomic, and geographical situation of the family as well as by the needs and condition of the individual client. Birth planning and complication readiness prior to the development of a complication is key to survival.
  6. Nepal Study Less than 50% of families of women who died in pregnancy, delivery or postpartum, recognized the problem. 36% decided within 2 hours to seek care and get transport. 15% decided in 2 to 23 hours to seek care and get transport. 29% made the decision and arranged transport 1 to 8 or more days after recognition of a life-threatening complication. Source: MOH, Nepal 1998. The interval from onset to death for antepartum hemorrhage can be approximately 12 hours. The interval from onset to death for postpartum hemorrhage can be two hours. The hours required for making arrangements (which could have been made prior to the emergency) may define the line between survival and mortality. Sources: Maine 1991; MOH, Nepal 1998. Complications Cannot Be Reliably Predicted No formula or scoring system can reliably distinguish those who will develop complications from those who will not
  7. Good antenatal nutrition includes: Meeting the caloric needs Eating foods which supply specific micronutrients Providing micronutrient supplementation An underweight mother increases the likelihood of a low birth weight (LBW) baby; low iron intake contributes to anemia Clients should know What family planning (FP) methods are options postpartum How to access FP services What FP services are available Family Planning should include use of condoms for dual protection Mothers need to Understand the benefits of breastfeeding Become comfortable and familiar with the idea of breastfeeding Understand “exclusive” breastfeeding Know to expect (and demand) “immediate” breastfeeding Families of pregnant women need to know how to recognize the signs of complications as well as what to do and where to get help In Nepal, less than 50% of families of women who died recognized the problem Source: MOH, Nepal 1998. Voluntary HIV counseling and testing should be available to every pregnant woman--for public health reasons as well as for the benefit to the individual woman. Pre and post-test counseling is an essential part of managing HIV in pregnancy. Source: WHO and UNAIDS 1999.
  8. Syphilis Maternal-fetal transmission may be as high as 80%. Incidence of adverse effects on the fetus/infant due to untreated maternal syphilis reported in some studies was: Spontaneous abortion – 20% Perinatal death – 30% Congenital syphilis – 25% Source: WHO 1991. Tuberculosis Infants born to women with tuberculosis (TB) have an increased risk of morbidity and mortality in the neonatal period. Source: Figueroa-Damian and Arredondo-Garcia 2001.
  9. Severe anemia Mild or moderate anemia is not correlated with adverse pregnancy outcomes Severe anemia, however, (hgb <7 g/dL or hct <20%) is associated with increased preterm delivery, inadequate intrauterine growth, increased perinatal mortality and increased maternal mortality. Providers can screen for anemia by • Hemoglobin (hgb) by thin film/smear • Hematocrat (hct) test • Hemoglobin Color Scale, or • Clinical observation of the inferior conjunctiva of the eye, the nail beds and the palm. If any of these are pale, the woman is severely anemic. Other symptoms include shortness of breath and signs of heart failure. 50 to 80% of pregnant women have dependent edema; 85% of women with preclampsia/ eclampsia have edema. Although dependent edema is normal in 50 to 80% of women, generalized edema is not. Sources: Carroli, Rooney and Villar 2001; McDonagh 1996; Enkin et al 2000.
  10. Tetanus toxoid is An effective, stable, cheap toxoid which has been available for > 50 years and is produced in many developing countries. Effective in preventing neonatal tetanus (NNT),which causes approximately half a milliondeaths/year) and maternal tetanus, which is estimated to cause 30,000 deaths annually. Sources: Fauveau V et al 1993; Bennett JV 2000. Globally among all populations, iron deficiency (and its manifestation in anemia) is the single most prevalent nutrient deficiency condition. The World Health Organization (WHO) estimates put anemia prevalence at 52% among pregnant women. Source: MotherCare, John Snow, Inc. 2000. Iron Folate Supplements The International Nutritional Anemia Consultative Group, WHO and UNICEF have endorsed the following guidelines: • All women should consume daily iron folate supplements for 6 months during pregnancy. • Where anemia prevalence is <40%, women should receive supplements of 60 mg iron and 400micrograms of folate • In areas where anemia prevalence is high among pregnant women (³40%), women should continue the same dosage for 3 months into postpartum. Sources: Stoltzfus and Dreyfuss 1998; McDonagh 1996. Malaria – pregnancy is associated withincreased susceptibility to P. falciparum The case fatality rate for cerebral malaria in pregnant women approaches 50%. Source: Looareesuwan S et al 1985, in WHO 1991. The Cochrane database reviewed 15 trials and concluded that drugs given routinely during pregnancy for malaria reduce the incidence of low birth weight and anemia. A Kenya trial shows that intermittent treatment with SP (sulphadoxinepyrimethamine) is safe and effective for: Preventing malaria in the mother Preventing harmful consequences to the fetus that may result from placental malaria Source: Parise et al 1998. Hookworms can contribute significantly to anemia Hookworms are estimated to infect 1 billion people worldwide, including approximately 44 million pregnant women. Prevalance rates vary from 10 to 20% in dry areas to more than 80% in rural areas in the wet, humid tropics. From an analysis of studies in Nepal (pregnant women) and Zanzibar (non-pregnant women), it is estimated that eradication of hookworms in the study population could prevent 41 to 56% of moderate to severe anemia. Source: Stoltzfus RJ et al 1997. Iodine deficiency is associated with neonatal deaths, stillbirths and abortions. Iodine deficiency during pregnancy, when severe, will result in growth retardation, brain damage, mental retardation, increased perinatal mortality and other defects. Iodine supplementation is a very low-cost, effective nutritional intervention. Iodizing salt is an effective public health measure for preventing iodine deficiency Source: The LINKAGES Project. 2000. Maternal Nutrition: Issues and Interventions. Vitamin A Can be found in foods such as carrots, eggs, fish oil, liver and broccoli High doses of vitamin A can be unsafe during the first two months of pregnancy, but it is safe to give as much as 10,000 IU daily at any time during pregnancy Sources: Nutrition and Micronutrients in Pregnancy; IVACG 1998 In Nepal, Vitamin A supplementation of 23,300 IU on a weekly basis to nearly 45,000 women of reproductive age over a 3.5 year period was associated with a 40% decrease in maternal mortality. Source: Nutrition and Micronutrients in Pregnancy