This document provides information about a module on platelets, including the course outcomes, learning outcomes, and contents. The module aims to teach students about the structure and functions of platelets, including their role in adhesion, aggregation, and hemostasis. Key topics that will be covered include the structure of platelets, the granules contained within platelets, normal platelet counts, clinical conditions of platelet dysfunction, and treatments for thrombocytopenia.

1. Module-2
Topic name
PLATLETS
Sub code: BMLT1002
Sub Name: General physiology – (T)
Department: Department of MLT, SMAS
Faculty: A. Vamsi Kumar
Designation : Assistant professor

2. Course outcomes
On completion of this course, the student can be
able to:
• Perform ESR, PCV, & Teach blood cell functions

3. Learning outcomes
On completion of this course, the student can be able to:
1. Be able to diagram the structure of a mature platelet and show the location of: dense granules,
alpha granules, glycoprotein Ib, glycoprotein IIb/IIIa, and phospholipids.
2. Be able to list three functions of platelets.
3. Be able to construct a simple diagram that depicts the process of platelet adhesion. Include in the
drawing subendothelial collagen, von Willebrand factor, and glycoprotein Ib. Explain why
platelet adhesion to blood vessels does not occur under normal circumstances.
4. Similarly, be able to construct a simple diagram that shows the process of platelet aggregation;
include the release reaction (ADP), thromboxane synthesis, ADP and thromboxane receptors,
glycoprotein IIb/IIIa, and fibrinogen.
5. List three mechanisms that could lead to thrombocytopenia.
6. Be able to identify three methods of treating ITP and the mechanism by which they increase the
platelet counts.

4. Contents
1. „Define platelets
2. Structure of platelets
3. Properties of platelets
4. Granules of platelets
5. Functions of platelets
6. Normal count of platelets
7. Clinical conditions of platelet dysfunction

5. Importance of platelets

11. Reference
• Essentials of medical physiology Sembulingam
6th edition.