3. INTRODUCTION
Placenta is derived from the Greek word, plakuos, meaning
flat cake and this reflects its typical appearance.
Placenta is a fetal organ of pregnancy, which is responsible
for providing nutrition and oxygen to the fetus as well as
excretory function.
In Eutherian mammals, the embryo develops in the uterus
of mother. Placenta is not common to all mammals.
In prototherian, mammals are egg laying. Hence placenta is
not formed in uterus.
4. ANATOMY
Placenta is fleshy
weight – 500gm
Diameter – 15-20cm
Thickness – 2.5cm
Spongy to feel
Occupies 30% of the uterine wall
5. PLACENTA
This is a fetomaternal organ.
It has two components:-
Fetal part:- develops from the chorionic sac
Maternal part:- derived from the
endometrium
The placenta and the umbilical cord are the
transport system for substances between the
mother and the fetus.
6. STRUCTURE OF PLACENTA
Placenta is limited by the amniotic membrane on the fetal
side and by the basal plate on the maternal.
Amniotic membrane:- single layer of cuboidal
epithelium loosely attached to adjacent chorionic plate
and does not take part in placental formation.
Chorionic plate:- forms the roof of the placenta from
outside.
From inwards consists of
Syncytotrophoblast
Cytotrophoblast
Extraembryonic mesoderm with branches of umbilical
vessels
7. CONT…….
Basal plate:- forms the floor from outside and inward it
consist of
Compact and spongy layer of decidua basalis
Layer of Nitabuch
Cytotrophoblastic shell
syncytiotrophoblast
8.
9. TYPES OF PLACENTA
Placenta is classified in three ways:-
On the nature of contact
On the distribution of villi
On the basis of histology
On the nature of contact:-
Two types:-
Indeciduate type placenta:- villi are simple
projections, they lie in loose contact with uterus.
Deciduate type placenta
10.
11. CONT…….
On the basis of histology:-
Five types:-
Epitheliochorial placenta(e.g; pig, horse):-fetal chorion is in
contact with epithelium of uterus.
Syndeumose chorial placenta(e.g; sheep, cow):- The allanto-
chorionic with will pierce into the uterus of the mother.
Endothelio chorial placenta(e.g ;dog, carnivores):- the
chorion of fetus will come in contact with endothelium of mother’s
uterus.
Hemochorial placenta (e.g; bat, man, primates,
insectivores):- The chorion of fetus will float in the blood pools of
mother’s uterus.
Hemo endothelial placenta (e.g; rat, rabbit):- maternal blood
appears to be separated from the fetal blood only by the
endothelium of the chorionic capillaries.
12.
13. CONT……..
On the distribution of villi:-
Five types:-
Diffused type placenta:-The villi are uniformly
distributed on the surface of blastocyst. e.g: horses, pigs
Cotyledonary placenta:- Villi are arranged in groups.
e.g; cattle, sheep, goat
Intermediate type placenta:- rare type, shows free villi
on cotyledons.
Zonary placenta:- The villi are in the form of transverse
zones. e.g; carnivores (dog, cat)
Discoidal placenta:- villi are arranged in a circular plate
as in human and rodent placentae.
14.
15. FUNCTIONS
It help in respiratory function
Excretory function
Nutritional
It produces or metabolizes the hormones and
enzymes necessary to maintain the pregnancy.
Immunological function :- It transfer the
immunoglobulin(IgG) to the fetus and filters out the
potentially toxic harmful antibodies.
Endocrine functions
16. CONT…..
Barrier function:- acts as the protective barrier for
the fetus against in maternal blood.
Larger molecular size drugs like insulin, heparin are
transferred minimally.
Only IgG antibodies and antigens can pass placental
barrier in both directions.
17. PLACENTAL HORMONES
Human chorionic gonadotrophin :- it is a
glycoprotein with high content of sialic acid and
other carbohydratic residues. Its molecular weight
is about 30,000.
Chorionic growth hormone prolactin or
HPL :-it is secreted in increasing quantities by the
syncytotrophoblast cells from the first weeks of
pregnancy.
Its molecular wt. is about 18,500.
19. CONCLUSION
Placenta act as protective barrier for the fetus against
in maternal blood.
it help in respiratory functions.
It is responsible for providing nutrition and oxygen
to the fetus.
It produces or metabolize the hormones and
enzymes.