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PLACENTAL FUNCTION
PRESENTED BY
ABHILASHA VERMA
LECTURER
BARRIER
PROTECTION
STORAGE
EXCRETION
ENZYMATIC
IMMUNOLOGICAL
NUTRITION
RESPIRATION
ENDOCRINE 2
ABHILASHA VERMA
ENDOCRINAL FUNCTION
 Cytotrophoblastic layer of chorionic villi produce hcG hormone.
 It present in large quantity between 7th & 10th week ( Peak
production) and gradully decrease as pregnancy advances.
 Estrogen are produced by placenta in large amount throughout
pregnancy.
 Progesterone, produced in syntiotrophoblast in increasing quantity
until immediately before onset of labor when level falls ( Prepare
maternal tissues and uterus for fetus delivery)
 Human placental lactogen ( HPL), produced that involved in
lactogenic and metabolic processes in pregnancy.
 Production of HPL ↑ as level of hcG falls and continue throughout
pregnancy.
3ABHILASHA VERMA
RESPIRATION FUNCTION
 Placenta serves as fetus’s lung and allow transmission
oxygen.
 Fetus obtain oxygen and excrete Co2 through placenta.
 Oxygen from mothers Hb passes into fetal blood by simple
diffusion similarly fetus gives off Co2 into maternal blood.
 Oxygen inhale by mother diffuse into blood, then O2 reach
to circulatory system of fetus through umbilical cord.
 Placenta prevent chances of inhaling amniotic fluid.
4ABHILASHA VERMA
NUTRITION FUNCTION
• Main function to supply adequate nutrition like amino
acid, glucose, vitamins, mineral, lipids, water and
electrolyte are transferred across placental membrane.
• Foods from maternal diet broken down into the simpler
forms and reaches to placental site.
• Placenta selects these substance according to
requirement.
• Breaks down complex nutrient into compounds that can
be used by fetus.
Protein- Amino acids
Carbohydrate- Glucose
Fat- Fatty acid.
5ABHILASHA VERMA
STORAGE FUNCTION
• Placenta store glucose, iron and vitamins.
• Glucose stored in glycogen form and gets reconverted to
glucose when required.
6ABHILASHA VERMA
EXCRETION FUNCTION
• Co2 is major substance excreted from fetus.
• Excretion of bilirubin formed during RBC breakdown.
• Excreation of small amount of urea and uric acid.
• Placenta acts like kidney, it filter blood to eliminates
harmful substances.
7ABHILASHA VERMA
PROTECTION FUNCTION
• Placental membrane has limited barrier function.
• Maternal IgG, gets passed to the fetus to provide
immunity for baby for first 3 months after birth.
• Most drugs also crosses the barrier and reaches to
fetus.
8ABHILASHA VERMA
ENZYMATIC FUNCTION
• Phospholipase, synthesize arachidonic acid
• Oxytocinase nutralize oxytocin.
• Serve as protective barrier for fetus against noxious
agents circulating in maternal blood.
• Placental hormone have immunosuppressive effects.
9ABHILASHA VERMA
BARRIER FUNCTION
IMMUNOLOGICAL FUNCTION
10ABHILASHA VERMA

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Placental function

  • 3. ENDOCRINAL FUNCTION  Cytotrophoblastic layer of chorionic villi produce hcG hormone.  It present in large quantity between 7th & 10th week ( Peak production) and gradully decrease as pregnancy advances.  Estrogen are produced by placenta in large amount throughout pregnancy.  Progesterone, produced in syntiotrophoblast in increasing quantity until immediately before onset of labor when level falls ( Prepare maternal tissues and uterus for fetus delivery)  Human placental lactogen ( HPL), produced that involved in lactogenic and metabolic processes in pregnancy.  Production of HPL ↑ as level of hcG falls and continue throughout pregnancy. 3ABHILASHA VERMA
  • 4. RESPIRATION FUNCTION  Placenta serves as fetus’s lung and allow transmission oxygen.  Fetus obtain oxygen and excrete Co2 through placenta.  Oxygen from mothers Hb passes into fetal blood by simple diffusion similarly fetus gives off Co2 into maternal blood.  Oxygen inhale by mother diffuse into blood, then O2 reach to circulatory system of fetus through umbilical cord.  Placenta prevent chances of inhaling amniotic fluid. 4ABHILASHA VERMA
  • 5. NUTRITION FUNCTION • Main function to supply adequate nutrition like amino acid, glucose, vitamins, mineral, lipids, water and electrolyte are transferred across placental membrane. • Foods from maternal diet broken down into the simpler forms and reaches to placental site. • Placenta selects these substance according to requirement. • Breaks down complex nutrient into compounds that can be used by fetus. Protein- Amino acids Carbohydrate- Glucose Fat- Fatty acid. 5ABHILASHA VERMA
  • 6. STORAGE FUNCTION • Placenta store glucose, iron and vitamins. • Glucose stored in glycogen form and gets reconverted to glucose when required. 6ABHILASHA VERMA
  • 7. EXCRETION FUNCTION • Co2 is major substance excreted from fetus. • Excretion of bilirubin formed during RBC breakdown. • Excreation of small amount of urea and uric acid. • Placenta acts like kidney, it filter blood to eliminates harmful substances. 7ABHILASHA VERMA
  • 8. PROTECTION FUNCTION • Placental membrane has limited barrier function. • Maternal IgG, gets passed to the fetus to provide immunity for baby for first 3 months after birth. • Most drugs also crosses the barrier and reaches to fetus. 8ABHILASHA VERMA
  • 9. ENZYMATIC FUNCTION • Phospholipase, synthesize arachidonic acid • Oxytocinase nutralize oxytocin. • Serve as protective barrier for fetus against noxious agents circulating in maternal blood. • Placental hormone have immunosuppressive effects. 9ABHILASHA VERMA BARRIER FUNCTION IMMUNOLOGICAL FUNCTION