OsteoarthritisAdam Rinde, NDNaturopathic PhysicianSound Integrative Health7/11/08 @ Natures Pantry
Key PointsPain relief is available in a non-pill form!Joint replacement can be preventedYou can take charge of your pain
Osteoarthritis: DescriptionOsteoarthritis: a disease effecting any joint with associated alteration of cartilageAlso known as:Degenerative Joint DiseaseOsteoarthrosisHypertrophic Osteoarthritis.
Osteoarthritis
OsteoarthritisPrimary Osteoarthritis:Associated with gradual aging-related destruction of cartilage in joint-space.Secondary OsteoarthritisUsually secondary to trauma/overuse, repetitive strain, and subsequent faulty repair and regeneration of cartilage.
Epidemiology of OAThe #1 joint-causing disorder that begins asymptomatically in the 20’s and 30’s and becomes extremely common by the age of 70.By the age of 40 most people have some change in weight bearing joints, although relatively few have symptoms. OA affects almost all vertebrates
Osteoarthritis: Epidemiologyoccurs in whales, dolphins, and porpoises.Does not occur in Bats which hang upside down.  This finding suggest that it is an ancient Paleozoic mechanism of repair and remodeling rather than a disease in the usual sense.
Osteoarthritis: how does it happenA Cartilage trauma combined withFaulty repairFaulty regenerationFaulty remodelingLeading to Deformed cartilage frictionLoss of function
OA SymptomsGradual onset usually involving one or a few jointsPain is the earliest symptom and is usually worsened with exercise and relieved by restMorning stiffness follows inactivity but lasts <15-30 minutes and lessens with movementAs OA progresses joint motion diminishes, tenderness and crepitus sensations appear and flexion contractures may occur.Pathologic changes can cause joint enlargement
OA symptomsOA of the cervical and lumbar vertebrae can lead to myelopathy or radiculopathyHip OA isCharacterized by gradually increasing rigidity and loss of range of motion.Pain may be felt in the inguinal (groin) area or referred to the kneeKnee OACartilage is lost in the medial aspect in 70% of the casesThe ligaments become lax and the joint less stable with local pain arising from the ligaments and tendonsTenderness on palpation and pain on passive motion are relatively late signsHandsthe base of the thumb, where the thumb and wrist come together (the trapezio-metacarpal, or basilar, joint)at the end joint closest to the finger tip (the distal interphalangeal or DIP joint)at the middle joint of a finger (the proximal interphalangeal or PIP joint)It also often develops in the wrist.
Osteoarthritis: DiagnosisDiagnosis is confirmed by x‑rays.Report may describe degree of joint space narrowingSubchondral SclerosisPresence of  osteophytesPeriodic X-rays useful in tracking progress of therapies.
Treatment Options for Osteoarthritis
Therapeutic GoalsPreserve Quality of Life by reducing disabilityReduce Pain and InflammationPrevent/Arrest cartilage degeneration (joint space narrowing)Utilize conservative therapies for long-term management Reduce reliance on NSAID Or OpiodsPrevent need for higher invasive therapies
OA Treatment StrategyReduce aggravating factors promoting destruction of joint cartilage Restore  and maintain healthy joint biomechanicsReduce pain and modulate chronic inflammatory state.Stimulate healthy cartilage regeneration and repair
OA Treatment: ErgonomicsConsider home devices such as grab bars in the tub enclosure, raised toilet seatsAvoid soft deep chairs and recliners from which arising is difficultAvoid pillows under the knees as this encourages contracturesSit in straight chairs without slumping
OA Treatment :ErgonomicsSleep in a firm bed with a bed boardUse a car seat designed for comfort
OA treatment: ExerciseExercise/Physical therapy: Daily stretching importantLocal application of moist heat especially before exercise sPerform postural exerciseResistance Training Quadriceps strengthening important (for Hip and Knee)Try not to immobilize (stay active)Rest every 4-6 hours in the daytime to allow rehydraton of cartilage and balance with exercise and use
OA treatment: ExerciseCardiovascular Exercise to promote weight reduction/weight managementAt least 5 days per week of 30 minutes at 70% of your maximum Heart RateChoose low impact forms of exerciseWalking, Golf, bicycle, elliptical, swimming,cross country skiing nordic-trackWater jogging
Manual Therapy Muscle Release Therapy
Active Isolated Stretching
Neuromuscular ReeducationTherapeutic ExerciseRe-conditioning compensated muscle groups
Building a strong foundation of joint support
Reducing excess force on jointsAcupunctureMay promote healingMay provide pain relief and improved joint function
Diet:	Low-inflammatoryOmega-3-rich dietWild-caught salmonCODOrganic Vegetables and Fruit5-7 servings are fruits and vegetables a day Kiwi, Papaya, PineappleLimited Chicken and Cow IntakeAvoid Food Sensitivities (especially Nightshades)Fiber rich (at least 30 g/day)Low processed foodsLow simple sugarsNo Transfats
Neutraceuticals for OAGlucosamine and Chondrotoin Sulfate Niacinamide May raise liver enzymesVitamin D (check levels through your Dr.)
Polyunsaturated Fatty Acids (PUFAS)Fish OilContains omega-3 essential fatty acidsChoose mercury freeMarine Lipid ExtractPerna canniliculusGreen lipped musselsAnother form of PUFA’sAlways discuss Fish Oil supplementation with your Dr. as Fish Oil may interact with Blood Thinners.
Supplementation: Cartilage protective/stimulatory?Avocado Soybean Unsulfoniables (ASU)A phytosterol that has been studied reduce pain and inflammation in OA.It may protect further cartilage damage.
Anti-inflammatory Proteolytic enzymesBromelainPapainRutinPeptizym
OA treatments;Botanical MedicineAnti-inflammatory herbs 	Devils ClawWillow Bark GingerTurmericNote: some of these may interact with anti-coagulants, check with physician
Antioxidant SupplementationUsually can be obtained through a quality daily multivitaminVitamin CVitamin AVitamin KVitamin ESeleniumZinc
Reduce InflammationIntraarticular InjectionsProlotherapygrowth factors or growth factor stimulator injectionsViscosupplementionHylagen (injectable synthetic hyularonic acid)FDA approved for knee injectionShow effective for Knees (not yet for hips)Corticosteroid Injections
Drug interventionsSimple AnalgesicAcetaminophen (Tylenol) OTC pain relieversCan prolong the halflife of warfafinNSAIDCox-2 Inhibitors (Celebrex)Know the warnings (ie. Cardiovascular/Gastroinestinal)Be assessed for risk of GI bleeding before taking Know the risks of taking long termKnow when they are beneficial and when they are not.Try and use for the shortest amount of time possible at the lowest effective dose.TramadolSynthetic Central Acting Opoid Used for severe pain
SurgeryKnee ArthroplastyReplacement usually has road-life of 10-12 yearsHip ArthroplastyUsually last 20 years

Osteoarthritis with Naturopathic Medicine

  • 1.
    OsteoarthritisAdam Rinde, NDNaturopathicPhysicianSound Integrative Health7/11/08 @ Natures Pantry
  • 2.
    Key PointsPain reliefis available in a non-pill form!Joint replacement can be preventedYou can take charge of your pain
  • 3.
    Osteoarthritis: DescriptionOsteoarthritis: adisease effecting any joint with associated alteration of cartilageAlso known as:Degenerative Joint DiseaseOsteoarthrosisHypertrophic Osteoarthritis.
  • 4.
  • 5.
    OsteoarthritisPrimary Osteoarthritis:Associated withgradual aging-related destruction of cartilage in joint-space.Secondary OsteoarthritisUsually secondary to trauma/overuse, repetitive strain, and subsequent faulty repair and regeneration of cartilage.
  • 6.
    Epidemiology of OAThe#1 joint-causing disorder that begins asymptomatically in the 20’s and 30’s and becomes extremely common by the age of 70.By the age of 40 most people have some change in weight bearing joints, although relatively few have symptoms. OA affects almost all vertebrates
  • 7.
    Osteoarthritis: Epidemiologyoccurs inwhales, dolphins, and porpoises.Does not occur in Bats which hang upside down. This finding suggest that it is an ancient Paleozoic mechanism of repair and remodeling rather than a disease in the usual sense.
  • 8.
    Osteoarthritis: how doesit happenA Cartilage trauma combined withFaulty repairFaulty regenerationFaulty remodelingLeading to Deformed cartilage frictionLoss of function
  • 9.
    OA SymptomsGradual onsetusually involving one or a few jointsPain is the earliest symptom and is usually worsened with exercise and relieved by restMorning stiffness follows inactivity but lasts <15-30 minutes and lessens with movementAs OA progresses joint motion diminishes, tenderness and crepitus sensations appear and flexion contractures may occur.Pathologic changes can cause joint enlargement
  • 10.
    OA symptomsOA ofthe cervical and lumbar vertebrae can lead to myelopathy or radiculopathyHip OA isCharacterized by gradually increasing rigidity and loss of range of motion.Pain may be felt in the inguinal (groin) area or referred to the kneeKnee OACartilage is lost in the medial aspect in 70% of the casesThe ligaments become lax and the joint less stable with local pain arising from the ligaments and tendonsTenderness on palpation and pain on passive motion are relatively late signsHandsthe base of the thumb, where the thumb and wrist come together (the trapezio-metacarpal, or basilar, joint)at the end joint closest to the finger tip (the distal interphalangeal or DIP joint)at the middle joint of a finger (the proximal interphalangeal or PIP joint)It also often develops in the wrist.
  • 11.
    Osteoarthritis: DiagnosisDiagnosis isconfirmed by x‑rays.Report may describe degree of joint space narrowingSubchondral SclerosisPresence of osteophytesPeriodic X-rays useful in tracking progress of therapies.
  • 12.
    Treatment Options forOsteoarthritis
  • 13.
    Therapeutic GoalsPreserve Qualityof Life by reducing disabilityReduce Pain and InflammationPrevent/Arrest cartilage degeneration (joint space narrowing)Utilize conservative therapies for long-term management Reduce reliance on NSAID Or OpiodsPrevent need for higher invasive therapies
  • 14.
    OA Treatment StrategyReduceaggravating factors promoting destruction of joint cartilage Restore and maintain healthy joint biomechanicsReduce pain and modulate chronic inflammatory state.Stimulate healthy cartilage regeneration and repair
  • 15.
    OA Treatment: ErgonomicsConsiderhome devices such as grab bars in the tub enclosure, raised toilet seatsAvoid soft deep chairs and recliners from which arising is difficultAvoid pillows under the knees as this encourages contracturesSit in straight chairs without slumping
  • 16.
    OA Treatment :ErgonomicsSleepin a firm bed with a bed boardUse a car seat designed for comfort
  • 17.
    OA treatment: ExerciseExercise/Physicaltherapy: Daily stretching importantLocal application of moist heat especially before exercise sPerform postural exerciseResistance Training Quadriceps strengthening important (for Hip and Knee)Try not to immobilize (stay active)Rest every 4-6 hours in the daytime to allow rehydraton of cartilage and balance with exercise and use
  • 18.
    OA treatment: ExerciseCardiovascularExercise to promote weight reduction/weight managementAt least 5 days per week of 30 minutes at 70% of your maximum Heart RateChoose low impact forms of exerciseWalking, Golf, bicycle, elliptical, swimming,cross country skiing nordic-trackWater jogging
  • 19.
    Manual Therapy MuscleRelease Therapy
  • 20.
  • 21.
  • 22.
    Building a strongfoundation of joint support
  • 23.
    Reducing excess forceon jointsAcupunctureMay promote healingMay provide pain relief and improved joint function
  • 24.
    Diet: Low-inflammatoryOmega-3-rich dietWild-caught salmonCODOrganicVegetables and Fruit5-7 servings are fruits and vegetables a day Kiwi, Papaya, PineappleLimited Chicken and Cow IntakeAvoid Food Sensitivities (especially Nightshades)Fiber rich (at least 30 g/day)Low processed foodsLow simple sugarsNo Transfats
  • 25.
    Neutraceuticals for OAGlucosamineand Chondrotoin Sulfate Niacinamide May raise liver enzymesVitamin D (check levels through your Dr.)
  • 26.
    Polyunsaturated Fatty Acids(PUFAS)Fish OilContains omega-3 essential fatty acidsChoose mercury freeMarine Lipid ExtractPerna canniliculusGreen lipped musselsAnother form of PUFA’sAlways discuss Fish Oil supplementation with your Dr. as Fish Oil may interact with Blood Thinners.
  • 27.
    Supplementation: Cartilage protective/stimulatory?AvocadoSoybean Unsulfoniables (ASU)A phytosterol that has been studied reduce pain and inflammation in OA.It may protect further cartilage damage.
  • 28.
  • 29.
    OA treatments;Botanical MedicineAnti-inflammatoryherbs Devils ClawWillow Bark GingerTurmericNote: some of these may interact with anti-coagulants, check with physician
  • 30.
    Antioxidant SupplementationUsually canbe obtained through a quality daily multivitaminVitamin CVitamin AVitamin KVitamin ESeleniumZinc
  • 31.
    Reduce InflammationIntraarticular InjectionsProlotherapygrowthfactors or growth factor stimulator injectionsViscosupplementionHylagen (injectable synthetic hyularonic acid)FDA approved for knee injectionShow effective for Knees (not yet for hips)Corticosteroid Injections
  • 32.
    Drug interventionsSimple AnalgesicAcetaminophen(Tylenol) OTC pain relieversCan prolong the halflife of warfafinNSAIDCox-2 Inhibitors (Celebrex)Know the warnings (ie. Cardiovascular/Gastroinestinal)Be assessed for risk of GI bleeding before taking Know the risks of taking long termKnow when they are beneficial and when they are not.Try and use for the shortest amount of time possible at the lowest effective dose.TramadolSynthetic Central Acting Opoid Used for severe pain
  • 33.
    SurgeryKnee ArthroplastyReplacement usuallyhas road-life of 10-12 yearsHip ArthroplastyUsually last 20 years
  • 34.
    OA resourcesArthritis Foundation-LocalChapterNational Institute for Arthritis,Skin, and Musculoskelatal Disorders.Health Clubs (International Health and Racquet Club)Vitalchoices.comPioneer Grocery
  • 35.
    Adam Rinde, NDContactInformationAppointments: 425-889-5894Email:drrinde@soundintegrative.comSound Integrative Health