Psoriasis is a chronic inflammatory skin disease characterized by red, scaly plaques. Ayurvedic management includes external therapies like oils and pastes, panchakarma procedures like snehana and swedana to clear doshas, and internal herbal formulations to address underlying imbalances and support tissue regeneration. Treatment protocols are tailored based on disease severity, duration and site of involvement, with mild cases treated initially with external applications and lifestyle changes, while more severe or longstanding psoriasis may require deeper panchakarma and herbal rasayana. The overall goals are to relieve symptoms, prevent relapse, and improve quality of life through a holistic approach addressing both medical and psychological aspects.
Sandhigata Vata is the type of pathogenesis involved in various disease conditions affecting the joints, e.g. osteoarthritis, rheumatoid arthritis, etc. and causing pain in affected joints.
Sandhigata Vata is the type of pathogenesis involved in various disease conditions affecting the joints, e.g. osteoarthritis, rheumatoid arthritis, etc. and causing pain in affected joints.
this is an ppt presentation by dr.b.arun kumar, who is working as a lecturer in MNR ayurvedic medical college, sangareddy, near hyderabad. in this presentation i given all details of virechana karma.
The Avabahuka disease is nearer to Frozen shoulder of musculoskeletal disorders.
Avabahuka is a Vata vikar as per Ayurveda that affects the ansha sandhi i.e. shoulder joint. The description available in Charak samhita, Sushruta samhita, Ashtanga Hridaya etc. The pain, stiffness, and decreased ROM range of motion is a classical feature of a frozen shoulder.
The treatment of frozen shoulder is possible in Ayurveda through drugs and various treatment modalities depending on the stages of the case.
Kinetrol HD 1/4 Turn Electric ActuatorKinetrol USA
A Hydraulic gear pump immersed in its own reservoir delivers pressurized oil to the vane-type 90° actuator via the control box, which contains non-return valves and solenoid valves to direct the flow into the actuator; with cam operated limit switches to control travel and (optionally) signal position to the user. The unpressurised side of the actuator is connected to the reservoir, so there is no net transfer of oil from reservoir to actuator. The pump and its motor run entirely on precision ball bearings, so that the friction and motor size can be minimized and life maximized; the efficiency resulting from this reduces the heating effect and allows 100% rating. A pressure release valve is built into the pump so that if the actuator load becomes jammed the torque is limited and dangerous over pressures or motor stalls are avoided.
this is an ppt presentation by dr.b.arun kumar, who is working as a lecturer in MNR ayurvedic medical college, sangareddy, near hyderabad. in this presentation i given all details of virechana karma.
The Avabahuka disease is nearer to Frozen shoulder of musculoskeletal disorders.
Avabahuka is a Vata vikar as per Ayurveda that affects the ansha sandhi i.e. shoulder joint. The description available in Charak samhita, Sushruta samhita, Ashtanga Hridaya etc. The pain, stiffness, and decreased ROM range of motion is a classical feature of a frozen shoulder.
The treatment of frozen shoulder is possible in Ayurveda through drugs and various treatment modalities depending on the stages of the case.
Kinetrol HD 1/4 Turn Electric ActuatorKinetrol USA
A Hydraulic gear pump immersed in its own reservoir delivers pressurized oil to the vane-type 90° actuator via the control box, which contains non-return valves and solenoid valves to direct the flow into the actuator; with cam operated limit switches to control travel and (optionally) signal position to the user. The unpressurised side of the actuator is connected to the reservoir, so there is no net transfer of oil from reservoir to actuator. The pump and its motor run entirely on precision ball bearings, so that the friction and motor size can be minimized and life maximized; the efficiency resulting from this reduces the heating effect and allows 100% rating. A pressure release valve is built into the pump so that if the actuator load becomes jammed the torque is limited and dangerous over pressures or motor stalls are avoided.
Psoriasis Ayurvedic Treatment Centre in Punjab, IndiaDr. Amit Dutta
Welcome to Dr. Amit Dutta’s :: AYUR - SUDHA ::: Advanced Ayurveda Skin Treatment Centre, a new kind of SKIN CARE organization. This site has information on Ayurveda and skin diseases, which is very good for your health and a leading Ayurvedic Medicine. Ayurveda is very popular in India and now is getting popular around the world. Herbs play a big part in Ayurveda, as does meditation.
Super Speciality Ayurveda Centre , FOR SKIN DISEASES is a Holistic Centre devoted to Ayurvedic Treatment & research run by highly qualified group of professionals.
AYUR SUDHA :: Super Speciality Ayurveda Centre
67 A , Guru Ravidass Nagar, Nr. Guru Ravidass Chowk
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+91.98033.56060
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info@ayursudha.com
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Global Generic Pharmaceutical Market - Qualitative and Quantitative AnalysisAiswariya Chidambaram
This report was presented at the Pharma Tech 2013 Conference - India A Game Changer in the Pharma Industry at Ahmedabad, India in December 2013. The presentation highlights the overview of the global generic pharmaceuticals market, with particular focus on the key market trends and challenges by therapeutic areas and geographies including the U.S, EU and India. List of key blockbuster drugs scheduled to lose patent protection between 2010 and 2020 have been included. Additionally impact of regulation on generic drugs by region and strategic recommendations for the success of market participants are also covered in this report.
We all know work is worship but now it is within the book only. We are now a days in bookworm. We read the books and analysis the data but we should go to grass rout to find out reality.
Skin Ailments Psoriasis By Dr. Darbha Aneeta
This is part of the HELP Talk series at HELP,Health Education Library for People, the worlds largest free patient education library www.healthlibrary.com.
Psoriasis is a skin disease that causes red, itchy scaly patches, most commonly on the knees, elbows, trunk and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It tends to go through cycles, flaring for a few weeks or months, then subsiding for a while or going into remission
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
3. WHAT IS PSORIASIS?
Inflammatory and
hyperplastic disease of
skin
Characterised by
erythema and elevated
scaly plaques
Chronic, relapsing
condition
Course of disease often
unpredictable
3
5. EPIDEMIOLOGY
Common skin disorder
Prevalence variable: ~ 0.3–2.5%
Prevalence equal in males and females
Estimated incidence: ~ 60 per 100,000 per year
5
6. AGE OF ONSET
Mean age: ~ 23–37 years
Current theory:
2 distinct peaks with possible genetic
associations
Early onset (16–22 years)
More severe and extensive
More likely to have affected first-degree family member
Late onset (57–60 years)
Milder form
Affected first-degree family members nearly absent
6
7. PSORIASIS IS A T-CELL MEDIATED, AUTOIMMUNE
DISEASE1
Current hypothesis:
Unknown skin antigens stimulate immune response
Antigen-specific memory T-cells are primary
mediators
Leads to impaired differentiation and
hyperproliferation of keratinocytes
7
13. TYPES OF PSORIASIS
Chronic plaque
Guttate
Flexural
Erythrodermic
Pustular
Localised and generalised
Local forms
Palmoplantar
Scalp
Nail (psoriatic
onychodystrophy)
13
14. CHRONIC PLAQUE PSORIASIS
Most common type –
affects approximately
85%
Features pink, well-
defined plaques with
silvery scale
Lesions may be single or
numerous
Plaques may involve
large areas of skin
Classically affects elbows,
knees, buttocks and scalp
14
19. GUTTATE PSORIASIS
Numerous and small
lesions – ~ 1 cm diameter
Pink with less scale than
plaque psoriasis
Commonly found on trunk
and proximal limbs
Typically seen in
individuals < 30 years
Often preceded by an
upper respiratory tract
streptococcal infection
1. 19
20. FLEXURAL PSORIASIS
Lesions in skin folds
articularly groin,
gluteal cleft, axillae
and submammary
regions
Often minimal or
absent scaling
May cause diagnostic
difficulty when genital
or perianal region is
affected in isolation
1 20
21. ERYTHRODERMIC PSORIASIS
Generalised erythema
covering entire skin surface
May evolve slowly from
chronic plaque psoriasis or
appear as eruptive
phenomenon
Patients may become
febrile, hypo/hyperthermic
and dehydrated
Complications include
cardiac failure, infections,
malabsorption and
anaemia
Relatively uncommon
21
22. PUSTULAR PSORIASIS
Two forms:
Localised form
More common
Presents as deep-seated
lesions with multiple small
pustules on palms and
soles
Generalised form
Uncommo Associated with
fever and widespread
pustules across the body
inflamed body surface
22
23. PALMOPLANTAR PSORIASIS
Can be
hyperkeratotic or
pustular
May mimic dermatitis
– look for psoriatic
manifestations
elsewhere to aid
diagnosis
Possibly aggravated
by trauma
23
24. SCALP PSORIASIS
Varies from minor
scaling with erythema
to thick
hyperkeratotic
plaques
May extend beyond
hairline
Patient scratching
may produce
asymmetric plaques
24
25. NAIL PSORIASIS
May be present in patients
with any type of psoriasis
Can take several forms:
Pitting: discrete, well-
circumscribed depressions
on nail surface
Subungual hyperkeratosis:
silvery white crusting under
free edge of nail with some
thickening of nail plate
Onycholysis: nail separates
from nail bed at free edge
‘Oil-drop sign’: pink/red
colour change on nail
surface
25
27. PSORIATIC ARTHRITIS
Approximately 5–20%
have associated arthritis
Five major patterns of
psoriatic arthritis:
Distal interphalangeal
involvement
Symmetrical polyarthritis
Psoriatic
spondylarthropathy
Arthritis mutilans
Oligoarticular,
asymmetrical arthritis
Clinical expressions
often overlap
27
28. DIAGNOSING PSORIASIS
Other dermatological disorders
can resemble psoriasis
Diagnosed clinically according to
appearance, distribution, history of lesions
and family history
Important to consider non-cutaneous
complications
28
31. MANAGING PSORIASIS
Goals of management
Tailor management to individual and address both
medical and psychological aspects
Improve quality of life
Achieve long-term remission and disease control
Minimise drug toxicity
Evaluate and monitor efficacy and suitability of individual
treatments
Remain flexible and respond to changing needs
31
32. MANAGING PSORIASIS
Before starting treatment
Establish relationship of trust with patient
Provide patient with information
Emphasise benign nature of disease
Explain that psoriasis tends to be chronic and
recurrent
32
34. FACTORS FOR SELECTION OF TREATMENT
Age: childhood, adolescence, young adult hood,
middle age,>60 yrs
Type of psoriasis: Plague, palmar, generalised
pustular, etc
Site and extent of involvement: localised to scalp,
palms, scattered plaques but <5% involvement:
generalised and >30% involement.
Previous treatment: Systemic glucocorticoids,
methotrexate
Associated medical disorders(eg. HIV, CVD)
Duration of Disease: <1month, <1 yr, >1yr
34
36. CHIKITSA
Sadya Virechana with Avipatti choornam-20gms for
1day
if saama lakshanas are seen - Shaddharana(5gm) /
panchakola choorna)
Mahatiktakam kashaya - 15ml bd for 1st week
Kaisoraguggulu - 1 tab bd for first week
Manasamitra vataka - 1 tab bd for 2 weeks
Gandhaka rasayan - 100mg with honey bd
(throughout)
Vitpala kera taila - external application followed by
sun exposure
36
37. PROTOCOL 2
MODERATE SYMPTOMS
HISTORY OF 2-6 MONTHS
AFFLICTED TO A LARGER AREA
37
38. CHIKITSA
Mahatiktakam ghrutha -15 gm(inc acc to agni bala X 7 days for
snehan (along with Abhyangam and sarvanga swedanam)
SadyoVirechana with Avipatti choorna - 20gm for 1st week.
Tiktakam kashaya - 15ml bd X 2 weeks
( if saama lakshanas are seen - 5-6gm shaddharana choorna
/gutika)
Kaishore Guggulu - 1 tab tds X 2 weeks
Arogya vardhini gutika - 1 tab tds X 2weeks
Gandhaka Rasayan- 100mg with honey (throughout)
Haridrakhandam -12gm bd X 2weeks
Manasmitra vatakam – 2 tabs bd X 2weeks
Vitpala kera taila - external application followed by sun exposure
38
40. PROTOCOL 3
SEVERE SYMPTOMS
HISTORY OF 6 MONTHS AND MORE
SPREAD EXTENSIVE AREAS
WITH SEVERE MENTAL STRESS
40
41. CHIKITSA
Starting with the previous protocol according to the bala,
avastha of Roga and Rogi, moving on to the additional
treatments.
Rookshana – Takra dhaara(musta,triphala,aragwadhadi)
Deepana-pachana -Panchakola churna with takra/usna
jala
Snehapana -dose acc. to agni bala. (Mahatiktakam
ghrutha/guggulutiktakam ghruta)
Abhyangam - vitpala
Swedana - usna jala snana, atapa sevan
Nasya - shadbindu taila
Vamana - madana,vacha,yashti,pippali+madhu
Virechana - avipatti choorna/ trivrut leha
41
42. FOLLOW UP
Need of Rasa-Rakta prasadana - Manobala
vardhaka -Rasayana chikitsa. Rasa-Rakta
parasadana
Mahamanjishtadi kashaya. 15ml bd X 1
month
Krumimudgar ras 1 hs X 1week
Manasamitra vataka 1bd X 1 month
Kalayana ghrutha 12gm hs X 1month
Gandhaka Rasayana 1tab bd X 1month
42
43. PATHYA
For a minimum of 3 months to control symptoms
and relapse
Ahara :Avoid Virudha, vidaahi , guru , abhishyandi,
navaanna, matsya, anupa mamsa, kanda varga. :
reduce the use of lavana : include more haridra,
rasona, pepper in the diet. : avoid pickles, dadhi at
night ,fermented food items. : avoid bakery items
(maida), oily and spicy foods. : strictly avoid egg,beef
and pork. : Avoid ready to cook items, tinned foods
etc. : avoid re-cooking refrigerated foods.
Vihaara : maintain hygiene in all aspects. : practice
Achara rasayana.
43
44. MANAGEMENT OF PSORIASIS: SUMMARY
Chronic, inflammatory disease of skin
Classic presentation characterised by
red, scaly plaques
Management should address both
medical and psychological aspects
Treatments include externaltherapy,
panchkarma, Rasa-Rakta prasadana -
Manobala vardhaka -Rasayana chikitsa.
Rasa-Rakta parasadana
44