A 35-year-old diabetic woman presented with altered consciousness for 12 days. She had a history of vomiting and abdominal pain. Examinations revealed she was disoriented with hypertonia and exaggerated reflexes. Investigations showed hyponatremia that had since corrected. MRI brain showed changes consistent with osmotic demyelination syndrome. She was diagnosed with diabetes, osmotic demyelination from hyponatremia, and erosive gastritis. She was treated with insulin, omeprazole, rehabilitation and discharged with advice to follow up in neurology.