Elephant shrews are small, insectivorous mammals found in Africa. They resemble rodents but have elongated snouts and scaly tails. Their sizes vary from 10-30 cm long and they weigh 50g to over 500g. They are insectivores, using their long noses to find prey like insects and their tongues to flick food into their mouths. Some eat small plants. The short-eared elephant shrew lives in southern Africa and inhabits desert and semi-desert areas, burrowing in sand. They breed in warm seasons, with females having multiple pregnancies. Elephant shrews have economic importance by controlling pest populations and being used for research and education.
this slide will help undergraduate student to study the difference between Poisonous and non poisonous snakes with examples, Poison apparatus, venom and its uses.
this slide will help undergraduate student to study the difference between Poisonous and non poisonous snakes with examples, Poison apparatus, venom and its uses.
in this you would find amazing pictures of some rare and beautiful animals with a long simple explanation, with sound by me........... so you needn't waste time in reading, just hear and enjoy my presentation!!!
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Order macroscelidea Shared By Abdul Qahar Buneri AWKUM BUner Campus
1.
2. Presented to sir zaheer AhmadPresented to sir zaheer Ahmad
Presented by Group 7thPresented by Group 7th
Asad aliAsad ali
Ibni AminIbni Amin
M IshaqM Ishaq
5. characteristicscharacteristics
Elephant shrews are small, quadrupedal,Elephant shrews are small, quadrupedal,
insectivorous mammals resemblinginsectivorous mammals resembling
rodents.rodents.
It have scaly tails, elongated snouts, andIt have scaly tails, elongated snouts, and
rather long legs for their size, which arerather long legs for their size, which are
used to move in a fashion like rabbits.used to move in a fashion like rabbits.
They are varying in size about 10 cm toThey are varying in size about 10 cm to
almost 30 cm, and weight is about 50 g toalmost 30 cm, and weight is about 50 g to
over 500 g.over 500 g.
6. characteristicscharacteristics
The The short-eared elephant shrewshort-eared elephant shrew has an average has an average
size of 150 mm.size of 150 mm.
Although the size of the trunk varies from oneAlthough the size of the trunk varies from one
species to another.species to another.
All are able to twist it about in search of food.All are able to twist it about in search of food.
Their lifespans are about two and a half to fourTheir lifespans are about two and a half to four
years in the wildyears in the wild
They have large canine teeth, and also highThey have large canine teeth, and also high
crowned crowned cheek teethcheek teeth like those of like those of ungulatesungulates..
Although mostly diurnal and very active.Although mostly diurnal and very active.
7. Feeding habitsFeeding habits
Elephant shrews mainly eat Elephant shrews mainly eat invertebratesinvertebrates, such, such
as insects, spiders, centipedes, millipedes,as insects, spiders, centipedes, millipedes,
and earthworms.and earthworms.
An elephant shrew uses its nose to find prey and uses itsAn elephant shrew uses its nose to find prey and uses its
tongue to flick small food into its mouth, much liketongue to flick small food into its mouth, much like
an anteater.an anteater.
Eating large prey can pose somewhat of a challenge forEating large prey can pose somewhat of a challenge for
an elephant shrew.an elephant shrew.
For example, a giant elephant shrew struggling with anFor example, a giant elephant shrew struggling with an
earthworm must first pin its prey to the ground with aearthworm must first pin its prey to the ground with a
forefoot.forefoot.
8. Feeding habitsFeeding habits
Then, turning its head to one side, it chewsThen, turning its head to one side, it chews
pieces off with its cheek teeth, much like a dogpieces off with its cheek teeth, much like a dog
chewing a bone. This is a sloppy process, andchewing a bone. This is a sloppy process, and
many small pieces of worm drop to the ground,many small pieces of worm drop to the ground,
these are simply flicked up with the tongue.these are simply flicked up with the tongue.
Some elephant shrews also feed on smallSome elephant shrews also feed on small
amounts of plant matter when available,amounts of plant matter when available,
especially new leaves, seeds, and small fruits.especially new leaves, seeds, and small fruits.
9. Geographic RangeGeographic Range
The short-eared elephant shrew mostlyThe short-eared elephant shrew mostly
inhabits in Namibia, southern Botswana,inhabits in Namibia, southern Botswana,
and South Africa.and South Africa.
10. HabitatHabitat
The animal only lives in desert and semi-The animal only lives in desert and semi-
desert areas of the countries in which it isdesert areas of the countries in which it is
found.found.
Also found in sparse grass cover orAlso found in sparse grass cover or
bushes that are a part of these dry areas.bushes that are a part of these dry areas.
They also burrow into the sand.They also burrow into the sand.
11. ReproductionReproduction
The breeding season is in the warmThe breeding season is in the warm
season.season.
In month of August and September.In month of August and September.
A female may have many pregnanciesA female may have many pregnancies
during one breeding season.during one breeding season.
12. Economic ImportanceEconomic Importance
Mainly feed insectivorous diets, insectsMainly feed insectivorous diets, insects
that might otherwise negatively affectthat might otherwise negatively affect
human health and agriculture.human health and agriculture.
research and education research and education
controls pest populationcontrols pest population