1. The document compares amalgam and composite for Class I and Class II cavity preparations. Amalgam is more durable but less esthetic, while composite is more technique sensitive but offers better esthetics.
2. For Class I cavities, amalgam preparations include all pits and fissures while composite only replaces defective areas. Retention forms also differ between the materials.
3. For Class II cavities, the outline and retention forms for amalgam and composite preparations depend on factors like the extent of decay and location of contacts or fractures. Modified preparations are also described that are more conservative.
This presentation specifically deals with the maxillary and mandibular Major connectors used in a cast partial denture. it also mentions the uses, advantages and disadvantages of each,
This presentation specifically deals with the maxillary and mandibular Major connectors used in a cast partial denture. it also mentions the uses, advantages and disadvantages of each,
A number of theories have been put forward for impressions. each having its own advantage and disadvantage.
Different spacers guide and aid in in making the desired impression with adequate pressure in the desired region of the arch in maxilla and mandible. different materials are used for spacers depending on the need.
A number of theories have been put forward for impressions. each having its own advantage and disadvantage.
Different spacers guide and aid in in making the desired impression with adequate pressure in the desired region of the arch in maxilla and mandible. different materials are used for spacers depending on the need.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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The pediatric dentistry in the restorative to the damaged tooth by the caries and the prevention for the further shedding and erupting of the permanent tooth.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
3. Content
1. General comparison between amalgam and composite
2. Class I cavity preparation
a. Modified class I
3. Class II cavity preparation
1.Outline
2.Retention
3.Resistance
4. Amalgam Composite
Esthetics Contraindicated Highly esthetic
Technique Sensitivity &
Isolation
Restorations that cannot be well isolated More technique sensitive & restoration
that can be appropriately isolated
Durability Long-lasting if handled well According to the ADA, expected lifetime
can be comparable to that of amalgam in
Class I & II if material’s handled well
Location Posterior teeth Anteriors & esthetically prominent areas
in posterior teeth
Cavity size more extensive (moderate-to-large) Class I
restorations
most small Class I restorations
Mechanical properties Higher mechanical properties Less mechanical properties more
subjected to wear
Caries Risk Patients w/ bad oral hygiene less risk of
recurrent caries due to self-sealing
properties
Patients w/ good oral hygiene high rate
of recurrent caries due to polymerization
shrinkage
Hazards on practitioner More hazardous due to mercury Hazardless
Repair Can’t be repaired Can be repaired
6. 1. The enamel must be supported with dentin to over
come the fracture.
Similarities
2. All angles must be rounded to prevent stress
magnitude on the tooth structure.
3. The walls must be either parallel or
perpendicular to the long axis of the teeth to
decreases the forces.
Incorrect
Correct
7. 1. Outline
Amalgam
• Includes all pits &
fissures and other
areas prone to caries
• width cavity within
1/4 to 1/3 intercuspal
distance
Composite
Limited to defected
areas and does not
have to extend to all
pits & fissures
Most conservative
manner
8. 2. Retention
Amalgam
• Macromechanical retention
undercuts: diverging
mesial & distal walls
smoother prepared walls
• Retention is dependent on
design of cavity
Composite
• micromechanical retention
Rough surfaces of prepared
walls
• Sometimes, a dentinal retention
groove or enamel bevel to
enhance the retention form
9. 3. Resistance Form
Amalgam
Resistance requires
bulkiness of cavity
Composite
3. Depth depends on extent of
defect can be stopped short
of the dentinal-enamel
junction if the caries process
also stops before the dentin is
reached
1. pulpal depth: not necessarily
uniform but usually 1 – 2 mm
1. Pulpal depth = min. 1.5 mm (floor
must consist of dentin)
2. Axial wall: Should be uniform
= 0.2 – 0.5 mm inside DEJ 2. Axial wall: Not necessarily
uniform
3. If caries extends deeper than
pulpal depth of 1.5 mm, only
the carious area is excavated
and a flat seat is established
around to not affect retention
form
10. Resistance Form
Amalgam
• Cavosurface Angle = 90° to
protect enamel rods
occlusal cavosurface bevel
is contraindicated
Composite
• Cavosurface Angle ≥ 90° to:
1. Increase surface area of enamel to be etched to
strengthen micromechanical bond
2. Esthetic blending of composite w/ tooth
structure
3. Ends of enamel rods are more effectively
etched, producing deeper microundercuts than
when only the sides of the rods are etched
12. Amalgam
1. Box shaped appearance
Composite
1. Scooped out appearance
3. occlusolingual
restoration used when
lingual fissure is connected
w/ the distal oblique groove
& distal pit on occlusal
aspect
2. bur must be slightly
inclined distally to
conserve the dentinal
support & strength of
marginal ridges &
distolingual cusp
2. Undermined marginal
ridge can be left in extensive
preparation & strengthened by
composite bonding
15. 1. Outline
Amalgam
• The occlusal
outline form of
proximal box is
determined
primarily by:
1. bucco-lingual
position of the
contact
2. extent of the
carious lesion
Conventional Composite
• used for moderate to very
large Class II composite
restoration
Occlusal outline Occlusal outline
Same principles in Class I cavity preparation except that external
outline is extended proximally toward defective proximal surface
16. …Outline
Amalgam
• Bucco proximal
margin, linguo
proximal
margin &
gingival floor
should be
extended to
include caries
& break the
contact with
the adjacent
tooth
Conventional Composite
• What dictates the facial,
lingual, and gingival
extension of the
proximal box?
1. The extent of the
carious lesion
2. Amount of old
restorative material
• not required to extend
the proximal box beyond
contact with the adjacent
tooth
Proximal boxProximal box
17. Amalgam
• Slot preparation:
Modified class
II cavity for
placement of
RMGIs (Resin
Modified Glass
Ionomer)
• Presence of infected carious dentin
on portion of either pulpal floor or
axial doesn’t indicate deepening
entire wall.
18. 2. Retention
Amalgam
• Rounded grooves within dentin at bucco
and linguo- proximal walls and gingival
floor
Conventional Composite
1. No dovetail
3. Gingival bevel
2. Cavosurface bevel to
increase surface area
• Gingival divergence faciolingual
width at gingiva greater than the
occlusal
3. No gingival bevel
2. No cavosurface bevel
1. Occlusal dovetail required for retention
19. • for smaller restorations
• preparation design: more rounded, less boxlike, & less uniform
in extension or depth compared to conventional
Composite Modified Class II
conservatively
remove the fault
create 90-degree
cavosurface
margins or greater
remove friable
tooth structure
20. • when only proximal surface is faulty, with
no lesions on the occlusal surface
• No beveling or secondary retention
indicated
• proximal box not extended onto occlusal
surface by more than 2 - 2.5 mm beyond
location of the proximal marginal ridge
• lesion on proximal surface but access
to lesion is possible through
facial/lingual surface rather than
through the marginal ridge in a
gingival direction
Direct access for caries removal
Box-only tooth preparation Facial/Lingual Slot Preparation
Composite Modified Class II
21.
22. References:
• Roberson, T. (2006). Sturdevant's art and science of operative
dentistry (5th ed.). St. Louis, Mo.: Mosby.
• http://iust.edu.sy/courses/class%20i%20and%20ii%20direct%20comp
osite%20and%20other%20tooth-colored%20restorations%20(1).pdf
• http://ccnmtl.columbia.edu/projects/virtechs2006/pdfs/opclass2prepha
ndout.pdf