Minimally invasive anterior spinal interbody fusion, known as oblique lumbar interbody fusion (OLIF), provides advantages over traditional anterior lumbar interbody fusion (ALIF) approaches. OLIF spares muscle and nerve trauma, avoids vascular structures, and allows single-position access to multiple lumbar levels. The authors' experience with 10 OLIF cases found good fusion rates, significant postoperative pain relief, and no procedure-related complications. OLIF restores disc height and biomechanics while achieving strong fusion through the anterior column.
Surgical Approaches to Acetabulum and PelvisBijay Mehta
Important surgical approaches to acetabulum and pelvis are described.
Ilioinguinal approach, Modified Stoppa Approach, Kocher lagenbeck Approach, Ilifemoral approach and extensile approaches are well illustrated and described.
This video explains Lumbar Disc Replacement in Detail. When degenerative disc disease begins to affect the spine this is called degenerative disc disease. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Lumbar Disc Replacement feel free to look us up online www.beverlyspine.com or www.santamonicaspine.com OR call toll free 1-8SPINECAL-1
Surgical Approaches to Acetabulum and PelvisBijay Mehta
Important surgical approaches to acetabulum and pelvis are described.
Ilioinguinal approach, Modified Stoppa Approach, Kocher lagenbeck Approach, Ilifemoral approach and extensile approaches are well illustrated and described.
This video explains Lumbar Disc Replacement in Detail. When degenerative disc disease begins to affect the spine this is called degenerative disc disease. This video highlights the history, epidemiology, and treatment options both conservative and surgical. If you or someone you know needs to be seen in regards to Lumbar Disc Replacement feel free to look us up online www.beverlyspine.com or www.santamonicaspine.com OR call toll free 1-8SPINECAL-1
Pain from acute vertebral fracture appears to be due in part to instability (non-union or slow union at the fracture site), while more than 1/3 of patients become chronically painful.
Traditional treatment for patients with painful VCFs includes bed rest, narcotic analgesics and bracing, resulting in increased pain because of acceleration bone loss and muscle weakness.
Posterior lumbar fusion vs Lumbar interbody fusion Evidence based.pptxsuresh Bishokarma
Lumbar degenerative disc diseases (LDDD): irreversible process in lumbar disk architecture.
Sparse literature to choose proper technique to address these pathology with or without fusion surgery.
A clear benefit of lumbar fusion surgery: lowered pain and disability scores.
Lumbar surgery rates have increased steadily over time, and hence related complications.
Evidence of the superiority of one technique over the other is sparse.
Surgery offers greater improvement compared with non-operative treatment in LDDD.
Surgery in disc herniation resulted in faster recovery, However no added benefit of fusion surgery.
There was no obvious disadvantage of posterolateral fusion without internal fixation in patient with spondylosis.
Among patients with lumbar spinal stenosis without spondylolisthesis, decompression plus fusion surgery may not result in better clinical outcomes.
In patient with spondylolisthesis with or without stenosis, fusion is more effective than laminectomy in achieving a satisfactory outcome. Decompression only had the least satisfactory outcome.
Patients who underwent interbody fusion may have significantly higher fusion rates compared to posterior lumbar fusion only.
TLIF has advantages over PLIF in the complication rate, blood loss, and operation duration. The clinical outcome is similar, with a slightly lower postoperative ODI score for TLIF.
In the end, The choice of technique is still greatly based on the surgeons’ preference and experience.
Full-endoscopic lumbar discectomy is an innovative, minimally invasive alternative to microdiscectomy for patients with symptomatic lumbar disc herniations. IELD and TELD offer two complementary surgical corridors to spinal pathology and allow for treatment of the vast majority of lumbar disc herniations. There is level one evidence suggesting that full-endoscopic spine surgery results in similar functional outcomes compared with microsurgical technique, and has a favorable rate of perioperative complications.
Medial patellofemoral ligament reconstruction ---- an update on techniques used. This lecture was taken by me at Trinity Arthroscopy Course, Chandigarh.
Operative treatment of osteoporotic spinal fracturesAlexander Bardis
Osteoporosis is a systemic disease, which results in :
progressive bone mineral loss
concurrent changes in bony architecture
leaving the spinal column vulnerable to compression fractures, usually after minimal or no trauma.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
ALL (antero-lateral ligament) - extra articular ACL reconstruction - basicsMilind Tanwar
history, need, how to reconstruct, when to reconstruct.
References: *Bonasia, Davide Edoardo et al. "Anterolateral Ligament Of The Knee: Back To The Future In Anterior Cruciate Ligament Reconstruction". Orthopedic Reviews 7.2 (2015)
Biomechanical Results of Lateral Extra-articular
Tenodesis Procedures of the Knee:
A Systematic Review. Erik L. Slette, B.A., Jacob D. Mikula, B.S., Jason M. Schon, B.S., Daniel C. Marchetti, B.A.,
Matthew M. Kheir, B.S., Travis Lee Turnbull, Ph.D., and Robert F. LaPrade, M.D., Ph.D.
TLIF is a minimally invasive approach towards removing degenerative discs in the lumbar spine. If you or someone you know may benefit from a Transforaminal Lumbar Interbody Fusion feel free to contact us 1-8SPINECAL-1, doctor@beverlyspine.com, doctor@santamonicaspine.com or via the internet www.santamonicaspine.com or www.beverlyspine.com
Pain from acute vertebral fracture appears to be due in part to instability (non-union or slow union at the fracture site), while more than 1/3 of patients become chronically painful.
Traditional treatment for patients with painful VCFs includes bed rest, narcotic analgesics and bracing, resulting in increased pain because of acceleration bone loss and muscle weakness.
Posterior lumbar fusion vs Lumbar interbody fusion Evidence based.pptxsuresh Bishokarma
Lumbar degenerative disc diseases (LDDD): irreversible process in lumbar disk architecture.
Sparse literature to choose proper technique to address these pathology with or without fusion surgery.
A clear benefit of lumbar fusion surgery: lowered pain and disability scores.
Lumbar surgery rates have increased steadily over time, and hence related complications.
Evidence of the superiority of one technique over the other is sparse.
Surgery offers greater improvement compared with non-operative treatment in LDDD.
Surgery in disc herniation resulted in faster recovery, However no added benefit of fusion surgery.
There was no obvious disadvantage of posterolateral fusion without internal fixation in patient with spondylosis.
Among patients with lumbar spinal stenosis without spondylolisthesis, decompression plus fusion surgery may not result in better clinical outcomes.
In patient with spondylolisthesis with or without stenosis, fusion is more effective than laminectomy in achieving a satisfactory outcome. Decompression only had the least satisfactory outcome.
Patients who underwent interbody fusion may have significantly higher fusion rates compared to posterior lumbar fusion only.
TLIF has advantages over PLIF in the complication rate, blood loss, and operation duration. The clinical outcome is similar, with a slightly lower postoperative ODI score for TLIF.
In the end, The choice of technique is still greatly based on the surgeons’ preference and experience.
Full-endoscopic lumbar discectomy is an innovative, minimally invasive alternative to microdiscectomy for patients with symptomatic lumbar disc herniations. IELD and TELD offer two complementary surgical corridors to spinal pathology and allow for treatment of the vast majority of lumbar disc herniations. There is level one evidence suggesting that full-endoscopic spine surgery results in similar functional outcomes compared with microsurgical technique, and has a favorable rate of perioperative complications.
Medial patellofemoral ligament reconstruction ---- an update on techniques used. This lecture was taken by me at Trinity Arthroscopy Course, Chandigarh.
Operative treatment of osteoporotic spinal fracturesAlexander Bardis
Osteoporosis is a systemic disease, which results in :
progressive bone mineral loss
concurrent changes in bony architecture
leaving the spinal column vulnerable to compression fractures, usually after minimal or no trauma.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
ALL (antero-lateral ligament) - extra articular ACL reconstruction - basicsMilind Tanwar
history, need, how to reconstruct, when to reconstruct.
References: *Bonasia, Davide Edoardo et al. "Anterolateral Ligament Of The Knee: Back To The Future In Anterior Cruciate Ligament Reconstruction". Orthopedic Reviews 7.2 (2015)
Biomechanical Results of Lateral Extra-articular
Tenodesis Procedures of the Knee:
A Systematic Review. Erik L. Slette, B.A., Jacob D. Mikula, B.S., Jason M. Schon, B.S., Daniel C. Marchetti, B.A.,
Matthew M. Kheir, B.S., Travis Lee Turnbull, Ph.D., and Robert F. LaPrade, M.D., Ph.D.
TLIF is a minimally invasive approach towards removing degenerative discs in the lumbar spine. If you or someone you know may benefit from a Transforaminal Lumbar Interbody Fusion feel free to contact us 1-8SPINECAL-1, doctor@beverlyspine.com, doctor@santamonicaspine.com or via the internet www.santamonicaspine.com or www.beverlyspine.com
XLIF is a minimally invasive approach towards removing degenerated discs in the lumbar spine and fusing them in a minimally invasive manner. If you or someone you know may benefit from a XLIF feel free to contact us 1-8SPINECAL-1, doctor@beverlyspine.com, doctor@santamonicaspine.com or via the internet www.santamonicaspine.com or www.beverlyspine.com
Colorado spine surgeon, Donald Corenman, MD provides a training on the benefits, use and technique of the O Arm surgical procedure. O Arm surgical technique benefits the surgeon and his team, along with the patient. Through reduced surgical time, increased accuracy of screw placement and reduction of incision size, O Arm is an effective surgical technique.
Tensor fascia lata[tfl] muscle pedicle grafting for avn hip dr mohamed ashraf...drashraf369
slide presentation of a very promising surgical technic for a very elusive condition called avascular necrosis of femoral head.good clinical and surgical demo by dr mohamed ashraf,HOD, govt TD medical college ,alleppey,kerala, india
Avascular necrosis of Hip - treatment modalities and current concepts.pptxVivek Jadawala
Slide 1 - Treatment modalities of Avascular Necrosis of Hip
JOURNAL CLUB PRESENTATION
Dr. Vivek Jadawala
PGY-3, Dept. of Orthopaedics,
JNMC, DMIHER
Slide 2 - image
slide 3 - image
slide 4 - Osteonecrosis of Hip - Osteonecrosis is death of living elements of involved bone (cells including marrow) with progressive destruction and alteration of bone architecture as a result of compromised vascularity.
Usually aseptic but may be incited by loss of vascularity from infection.
Slide 5 - Epidemiology - Male > Female
Average age group – 35 to 50 years
Bilateral Hip joints – 80 % of the cases
Most common site – Antero-lateral aspect of femoral head
Slide 6 - Blood supply of femoral head
Slide 7 - Classification of AVN: Ficat and Arlet -STAGE 0 :
X-ray : normal
MRI: normal
clinical symptoms: nil
STAGE I :
X-ray : normal or minor osteopenia
MRI: edema
bone scan: increased uptake
clinical symptoms: pain typically in the groin
Slide 8 - Stage I
Slide 9 - Stage II -
X-ray: mixed osteopenia and/or sclerosis and/or subchondral cysts, without any subchondral lucency (crescent sign)
MRI: geographic defect
Bone scan: increased uptake
clinical symptoms: pain and stiffness
Slide 10 - Stage III - X-ray: Crescent sign and eventual cortical collapse
MRI: same as plain radiograph
clinical symptoms: pain and stiffness +/- radiation to knee and limp
Slide 11 - Stage IV - X-ray: end-stage with evidence of secondary degenerative change
MRI: same as plain radiograph
clinical symptoms: pain and limp
Slide 12 - Stage IV
Slide 13 - image
Slide 14 - Steinberg staging of AVN
Slide 15 - Steinberg staging - STAGE 0:
- normal or non-diagnostic radiographs, MRI and bone scan of at risk hip (often contralateral hip involved, or patient has risk factors and hip pain)
STAGE I:
normal radiograph, abnormal bone scan and/or MRI
STAGE II:
- cystic and sclerotic radiographic changes
STAGE I AND II
A, mild: <15% head involvement as seen on radiograph or MRI
B, moderate: 15% to 30%
C, severe: >30%
Slide 16 - STAGE III:
- subchondral lucency or crescent sign
A, mild: subchondral collapse (crescent) beneath <15% of articular surface
B, moderate: crescent beneath 15% to 30%
C, severe: crescent beneath >30%
STAGE IV:
flattening of femoral head, with depression graded into
A, mild: <15% of surface has collapsed and depression is <2 mm
B, moderate: 15% to 30% collapsed or 2-4 mm depression
C, severe: >30% collapsed or >4 mm depression
Slide 17 - STAGE V:
- joint space narrowing with or without acetabular involvement
STAGE VI:
- advanced degenerative changes
Slide 18 - Association Research Circulation Osseous classification
Slide 19 - image
Slide 20 - Kerboul angle - Original classification was proposed on radiographs where he divided the necrotic region into small, medium and large regions:
Small - less than or equal to 160°
Medium - 161 to 199°
Large - 200 or more degrees.
Slide 21 - Modified Kerboul angle - based on MRI has much higher values as the MRI overestimates the necrotic region
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
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MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
1. Minimally invasive anterior spinal
interbody fusion- Oblique lumbar
interbody fusion
Dr . Manoranjitha kumari MCh
Dr. Manas Panigrahi MCh FACS
Dr M B V Prasad MS
Krishna Institute Of Medical Sciences,
2. Introduction
• Lumbar interbody fusion has become a
popular technique for treating spinal
conditions such as spondylolisthesis,
degenerative disc disease, recurrent disc
herniation, pseudarthrosis and spinal
deformity
3. Introduction....
• Inter body fusion procedures-
described by cloward 50 years ago
Various approaches:
PLIF
TLIF
ALIF
OLIF
XLIF
4. RATIONALE FOR ALIF
Superior biomechanical and perioperative
outcomes
• In a normal lumbar spine in the upright
standing position, the anterior and middle
weight-bearing columns of the spine support
approximately80%of the spinal load, and the
posterior column supports approximately
20%.
5. • However, with aging and the consequences of
the degenerative cascade, including
dehydration of the nucleus and repetitive
annular injuries reducing the height of the
disk, the weight-bearing distribution shifts so
that the posterior column supports a greater
percentage of the axial load
6. Matge G, Leclercq TA. Rationale for interbody fusion with threaded titanium
cages at cervical and lumbar levels: results on 357 cases. Acta Neurochir (Wien).
2000;142(4):425-434.
7. • With ALIF, an interbody fusion device is used
to redistribute the weight-bearing distribution
to the original ratio.
• According to the Woolf law, the fusion
potential increases if grafts are placed under
the direct compression that supports the
placement of the graft in the anterior column.
Mummaneni PV, Haid RW, Rodts GE. Lumbar interbody fusion: state-of
the-art technical advances. J Neurosurg Spine. 2004;1(1):24-30.
8. • Additionally, the anterior and middle columns
provide 90% of the more vascular osseous
surface area, and this wide cancellous bed for
graft contact enhances the fusion potential
over the posterolateral space
9. Advantages of anterior approach
• Compared with posterior approaches, the
retroperitoneal approach in OLIF spares
iatrogenic trauma to the paraspinal
musculature, posterior spinal nerves, and
posterior bony elements.
10. Advantages of anterior approach
• nerve root retraction and entrance into the
spinal canal are unnecessary, thereby
eliminating epidural scarring and perineural
fibrosis
Chung SK, Lee SH, Lim SR, et al. Comparative study of laparoscopic L5-S1 fusion
versus open mini-ALIF, with a minimum 2-year follow-up. Eur Spine J. 2003;12 (6):613-
617
11. Indications
• Degenerative disc disease with or without
radiculopathy
• Spondylolisthesis
• Failed posterior fusion
• Scoliosis
12. • Although there is ongoing debate as to
whether the anterior approach is better than
the posterior approach, Jiang et al reported in
a systematic review that clinical outcomes and
failed fusion rates were similar in both
techniques.
13. • Radiological outcomes, including height
restoration and focal and lumbar lordosis,
were superior in anterior approach, whereas
cost, blood loss, and operative time were
greater in ALIF compared with transforaminal
lumbar interbody fusion.
Jiang SD, Chen JW, Jiang LS. Which procedure is better for lumbar
interbody fusion: anterior lumbar interbody fusion or transforaminal lumbar
interbody fusion? Archives of Orthopaedic and Trauma Surgery.
2012;132(9):1259-1266.
16. Rao et al
Jan 2015
Neurosurgery
Post
Op pain relief
Mean VAS 0-
2.5
17. ‘Mayer’ described the technique of interbody
fusion Using retro periotoneal corridor
Mayer HM. A new microsurgical technique for minimally invasive anterior
lumbar interbody fusion. Spine (Phila Pa 1976) 1997;22:691-9.
18. Advantages of OLIF than direct
anterior approach
• Anterior to psoas muscle-
avoids injury to psoas muscle
and lumbar plexus there by
less incidence of cruralgia
• Away from peritoneum and
vasculature
( beware of ileolumbar vein and
transitional bifircation of great
vessels)
• Preserves sympathetic plexus-
decreased incidence of
retrograde ejaculation
19. Advantages of OLIF....
• Direct visualisation and
discectomy, easy to do
end plate preparation
• Can be performed L2-L3
to L4-L5
• Upto 3 level fusion can
be done using 4 cm
incion by “sliding
window” technique
Rodgers WB, Gerber EJ, Patterson J. Intraoperative and early postoperative complications in
extreme lateral interbody fusion: an analysis of 600 cases. Spine (Phila Pa 1976) 2011;36:26-32.
20. Advantages of OLIF
• Lesser incidence of hernias and ileus
• Decreased blood loss
• Increased surface area of the OLIF cage which
is 3 times more than TLIF cage gives better
and strong arthodesis
33. Our experience at KIMS
• 10 cases in 1 year, age ranging from 16 years-84 years, 3
female 7 male were treated
Primary Sx 8
PIVD 4
Listhesis 3
Sport injury 1
secondary 2
Failed back
instability
2
Single level 7
Two levels 3
Posterior
pedicle
screws
6
Lateral
interbody
rods
4
34. • Posterior pedicle screw fixation done in 5
patients at second stage within 48 hours
• Lateral interbody rod fixation – 3 patients on
the same sitting
• All patients iliac bone graft was used
• 2 patients with oseoporosis treated
cannulated screws with bone cement
35. • Average duration of surgery 120 minutes+/-15
minutes
• average blood loss 75 ml to 100 ml
• Average duration of stay 5-7 days
• Procedure related complication - nil
47. Discussion
• OLIF is a minimally invasive fusion procedure
• Lesser complication rate when compared to
ALIF
• Longterm follow up (5 and half years)of
patients with OLIF showed similar outcome as
that ALIF with lesser morbidity
Saraph V, Lerch C, Walochnik N, Bach CM, Krismer M, Wimmer C. Comparison of
conventional versus minimally invasive extraperitoneal approach for anterior
lumbar interbody fusion. Eur Spine J 2004;13:425-31.
48. Conclusion:
• OLIF restores the biomechanics of lumbar
spine by preserving disc space height achieves
strong fusion and helps in weight
transmission through anterior and middle
column of spine there by avoiding undue
stress on the posterior construct and
instrument failures.