Obesity is that, you have a high amount of fat in your body, and from that definition you can notice that, obesity is not about more weight, it's about more fat .
you will find in his presentation:(Body mass index (BMI),causes,Waist–hip ratio,Childhood obesity,complications and treatment)
My seminar Obesity by Hani
Obesity is a public health and policy problem because of its increase prevalence, costs and health effect. (WHO, 2012, National heart lung and blood institute. 2012)
. The risk factor for chronic disease are highly prevalence (Zindah, Belbeisi, Walke & Makdad 2008)
The obesity and the overweight are risk for number of chronic disease include diabetes cardio vascular disease and cancer (WHO,2010)
Obesity is that, you have a high amount of fat in your body, and from that definition you can notice that, obesity is not about more weight, it's about more fat .
you will find in his presentation:(Body mass index (BMI),causes,Waist–hip ratio,Childhood obesity,complications and treatment)
My seminar Obesity by Hani
Obesity is a public health and policy problem because of its increase prevalence, costs and health effect. (WHO, 2012, National heart lung and blood institute. 2012)
. The risk factor for chronic disease are highly prevalence (Zindah, Belbeisi, Walke & Makdad 2008)
The obesity and the overweight are risk for number of chronic disease include diabetes cardio vascular disease and cancer (WHO,2010)
Our body is composed of water, fat, bone and muscles.
Divided into:
Fat free mass- i.e. non fat elements which constitutes bone, muscle, water and tissues.
Body fat- i.e. essential and non essential fats.
This body fat contributes 5% of total body weight in men and 12% in women.
This ppt contains all the details about what is obesity, etiology, & mainly focuses on various methods of assessment of obesity from field tests to lab tests.
Effective treatment for obesity in Mindheal Homeopathy clinic ,Chembur, Mum...Shewta shetty
"Obesity- Obesity refers to excessive fat accumulation in the body. Mindheal homeopathy induces the patient to make a dietary and lifestyle changes to control obesity"/>
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
2. Deposite of fat:Deposite of fat:
►Addipose tissueAddipose tissue
►Subcutaneus fatSubcutaneus fat
►Arround the viitalArround the viital
organ. Such as ;organ. Such as ;
heart, kidney, liverheart, kidney, liver
e.t.ce.t.c
3. Deffination :Deffination :
► Obesity is aObesity is a medical conditionmedical condition in which excessin which excess body fatbody fat
has accumulated to the extent that it may have anhas accumulated to the extent that it may have an
adverse effect on health, leading to reducedadverse effect on health, leading to reduced
life expectancylife expectancy and/or increased health problems.and/or increased health problems.
► Obesity is an abnormal accumulation of body fat,Obesity is an abnormal accumulation of body fat,
usually 20% or more over an individual's ideal bodyusually 20% or more over an individual's ideal body
weight.weight.
► The (WHO) definition is:The (WHO) definition is:
a BMI greater than or equal to 25 is overweighta BMI greater than or equal to 25 is overweight
a BMI greater than or equal to 30 is obesitya BMI greater than or equal to 30 is obesity
► Obesity is when a person is carrying too much body fatObesity is when a person is carrying too much body fat
for their height and sexfor their height and sex
4. Ideal weight:Ideal weight:
►a weight that is believed to bea weight that is believed to be
maximally healthful for a person,maximally healthful for a person,
based chiefly on height butbased chiefly on height but
modified by factors such as gender,modified by factors such as gender,
age, build, and degree of muscularage, build, and degree of muscular
development.development.
►A person's optimum weightA person's optimum weight
10. Other indicator:Other indicator:
► Skin fold thickness (SFT)Skin fold thickness (SFT)
► WaistWaist
► Waist to hip ratio (WHR)Waist to hip ratio (WHR)
► Dual energy x-ray absorptionary(DEXA)Dual energy x-ray absorptionary(DEXA)
► Bop-pod ( Egg chaber)Bop-pod ( Egg chaber)
► Bio- electric empedance analysis (BIA)Bio- electric empedance analysis (BIA)
11. Type of cellType of cell
► Fat cells are used by the bodyFat cells are used by the body
to store excess caloriesto store excess calories
(energy) for future use.(energy) for future use.
► an average human body hasan average human body has
about 40 billion fat cells whichabout 40 billion fat cells which
can beas high as 100 billion fatcan beas high as 100 billion fat
cells in an obese person.cells in an obese person.
► The Subcutaneous layerThe Subcutaneous layer
(under the skin): They form the(under the skin): They form the
ugly bulges on the hips andugly bulges on the hips and
thighsthighs
► The Intra Peritoneal layerThe Intra Peritoneal layer ::
This gives rise to the appleThis gives rise to the apple
shaped obesity and all theshaped obesity and all the
health riskshealth risks
27. Fat burning foodFat burning food
► Asparagus = AsperginAsparagus = Aspergin
► Beets = Special Fe & cl which decrease fatBeets = Special Fe & cl which decrease fat
► Cabbage boil) = s & I2 clean the stomach & intestine mucousCabbage boil) = s & I2 clean the stomach & intestine mucous
membranemembrane
► Carrots = contain carotene rich A which decrease fatCarrots = contain carotene rich A which decrease fat
absorptionabsorption
► Raw Celery (lettuce type)Raw Celery (lettuce type)
► Cucumber = sulfur & silicon increase fat burningCucumber = sulfur & silicon increase fat burning
► Garlic = fat cleansing actionGarlic = fat cleansing action
► Lettuce = Wash the fatty cellLettuce = Wash the fatty cell
► Onion, Tomato, Broccoli,Onion, Tomato, Broccoli,
► Green teaGreen tea
► Raw apple ,Banana's , oats, Raw mango, Raw orange, grapeRaw apple ,Banana's , oats, Raw mango, Raw orange, grape
► spinachspinach
► citric food like lemon & limecitric food like lemon & lime
► peanut, yogurt(low fat)peanut, yogurt(low fat)
► Egg white), brown rice, red wheatEgg white), brown rice, red wheat
► Mushroom, cauliflower, corn, eggplant, red-cabbageMushroom, cauliflower, corn, eggplant, red-cabbage
► Lean meat, lean fish, salmon, tunaLean meat, lean fish, salmon, tuna
► lobsterlobster
► papaya, pear, pine-apple, watermelon, cherriespapaya, pear, pine-apple, watermelon, cherries
► Grape fruitGrape fruit
28. Safe drinking waterSafe drinking water
► Transports nutrients andTransports nutrients and
oxygen into cellsoxygen into cells
► Moisturizes the air inMoisturizes the air in
lungslungs
► Helps with metabolismHelps with metabolism
► Protects our vital organProtects our vital organ
► Helps our organs toHelps our organs to
absorb nutrients betterabsorb nutrients better
► Regulates bodyRegulates body
temperaturetemperature
► DetoxifiesDetoxifies
► Protects and moisturizesProtects and moisturizes
our jointsour joints
29. 11 benefits of drinking water11 benefits of drinking water
30. ““Kiss me” Diet planKiss me” Diet plan
► KK = keep= keep
► I = itI = it
► S = soS = so
► S = simple forS = simple for
meme
► Including food = GIIncluding food = GI
( green zone )( green zone )
► Limiting food = GILimiting food = GI
(Yellow zone)(Yellow zone)
► Eliminated food = GIEliminated food = GI
(Red zone)(Red zone)
► Green zone= <55 GIGreen zone= <55 GI
► Yellow zone =54-74 GIYellow zone =54-74 GI
► Red zone = >75 GIRed zone = >75 GI
35. Avoid crush/poor dietAvoid crush/poor diet
Listen to the bodyListen to the body
► Coronary heart diseaseCoronary heart disease
► HTNHTN
► NIDDMNIDDM
► ConstipationConstipation
► Joint painJoint pain
► Being out of breathBeing out of breath
► Poor life expectancyPoor life expectancy
► Produce free radicalProduce free radical
36. Rule’s for obese personRule’s for obese person
► Do not over-eat.Do not over-eat.
► Eat a variety of foods.Eat a variety of foods.
► Consider organically grown food.Consider organically grown food.
► Eat as much of your food raw or lightly-cooked as possible.Eat as much of your food raw or lightly-cooked as possible.
► Eat as much fresh fruit and vegetables as possible.Eat as much fresh fruit and vegetables as possible.
► Avoid drinks containing sugar or caffeine.Avoid drinks containing sugar or caffeine.
► Avoid sugars.Avoid sugars.
► Avoid processed and refined foods.Avoid processed and refined foods.
► Avoid hydrogenated trans-fatty acids. Use only certain oilsAvoid hydrogenated trans-fatty acids. Use only certain oils
for frying. Keep essential fats in balance.for frying. Keep essential fats in balance.
► Maintain high protein + low carb’s + low fat dietMaintain high protein + low carb’s + low fat diet