The document discusses the null hypothesis for a paired sample t-test. It explains that a paired sample t-test compares a dependent variable between two measurements of the same sample. It provides a template for writing the null hypothesis as "There is no significant difference in [dependent variable] between [first measurement] and [second measurement]." Two examples applying this template to compare red blood cell counts before and after moving locations, and wellbeing survey scores before and after listening to music, are given.