The document discusses the differences between questions of difference, relationship, and goodness of fit. It provides examples to illustrate each type of question. A question of difference compares two or more groups on some outcome, like comparing younger and older drivers' average driving speeds. A question of relationship examines whether a change in one variable causes a change in another, such as the relationship between age and flexibility. A question of goodness of fit assesses how well a claim matches reality, such as whether a salesman's claim of software effectiveness fits the results of user testing.