Neonatal sepsis is a clinical syndrome of systemic illness accompanied by bacteria in the blood occurring in the first month of life. It can be early-onset within the first week of life, usually acquired during birth from the mother, or late-onset between 1 week to 1 month of life, often from the hospital environment. Symptoms are non-specific but can include temperature irregularities, poor feeding, or respiratory distress. Treatment involves blood cultures, antibiotics like ampicillin and gentamicin, and supportive care for complications involving various organ systems. Future treatments may involve immunotherapies and blocking inflammatory responses.

1. NEONATAL SEPSIS

2. DR. CRISBERT I. CUALTEROS

38. Signs & Symptoms of sepsis in infant yes no Full dx eval. Emperic Tx Gestational age <37 wks Maternal temp <102 F S/sx of sepsis in infant Maternal temp >102F no yes Full eval. w/ empiric Rx Limited eval. Observe 48H If sepsis suspected, full eval & empiric Rx >37 wks Limited eval Observe 48H If sepsis suspected, full eval & empiric Rx No evaluation No therapy Observe min, 48 H