This document discusses multi-pressure refrigeration systems. It explains that single-stage systems have limitations at very low evaporator or high condenser temperatures due to increased losses. Multi-stage systems address this by using multiple compression stages to reduce the temperature lift in each stage. Types of multi-stage systems include multi-compression, multi-evaporator, and cascade systems. Flash gas removal and intercooling can further improve the performance of multi-stage systems. Cascade systems use multiple refrigerants matched to different temperature ranges.